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Neurostimulation

Spinal Cord and Nerve Stimulation for Spinal Cord Injury

N/A
Waitlist Available
Led By Gail Forrest, Ph.D.
Research Sponsored by Kessler Foundation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from enrollment to the end of treatment at 4 weeks
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to test a new treatment for people with spinal cord injuries in the neck region, who have difficulty using their hands. The treatment involves combining spinal cord and nerve stimulation with physical therapy training to

Who is the study for?
This trial is for individuals with spinal cord injuries in the neck region, leading to arm and hand paralysis or weakness. Participants should be seeking to improve their ability to perform daily tasks using their arms and hands.
What is being tested?
The study tests a combination of spinal cord transcutaneous stimulation and peripheral nerve stimulation paired with physical therapy training, aiming to enhance arm and hand function in those affected by spinal cord injury.
What are the potential side effects?
Potential side effects are not explicitly listed but may include discomfort at the stimulation site, muscle fatigue from therapy sessions, or skin irritation due to equipment use.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from enrollment to the end of treatment at 4 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and from enrollment to the end of treatment at 4 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
F-wave
GRASSP
Maximal voluntary grip strength
+3 more
Secondary study objectives
Capabilities of Upper Extremity Questionnaire (CUE-Q)
Functional Neurophysiological assessment (FNPA)
International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) - ASIA Impairment Scale (AIS)
+2 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: scTS+PNSExperimental Treatment1 Intervention
This arm will receive 20 sessions of paired application of spinal cord transcutaneous stimulation (scTS) and peripheral nerve stimulation (PNS) followed by scTS combined with physical therapy.
Group II: scTSActive Control1 Intervention
This arm will receive 20 sessions of spinal cord transcutaneous stimulation (scTS) combined with physical therapy.

Find a Location

Who is running the clinical trial?

Kessler FoundationLead Sponsor
183 Previous Clinical Trials
11,159 Total Patients Enrolled
Gail Forrest, Ph.D.Principal InvestigatorKessler Foundation
~9 spots leftby Nov 2026