Mirror Speech Entrainment for Aphasia

(MSE Trial)

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of South Florida

No Placebo Group

Trial Summary

What is the purpose of this trial?

The goal of this clinical trial is to test the use of voice personalization through artificial intelligence (AI) voice cloning on speech entrainment tasks to improve language production of persons with aphasia (PWA). The main question the study aims to answer is: - What is the impact of personalized voice on speech entrainment in PWA compared to traditional speech entrainment? Speech entrainment is a technique used by speech-language pathologists to improve the speech production of PWA. Traditionally, speech therapists act as the model for participants to speak along with to improve their speech production. This study proposes the use of one's own voice (digitally altered) to improve speech production. The study uses a mobile health approach to administer speech entrainment treatment through a mobile app. * Smartphones with the mobile app pre-installed will be mailed to participants at no cost. * Participants will complete treatment in the comfort of their homes. * The experimental treatments involve: mirror speech entrainment (speaking along to one's own voice) and traditional speech entrainment (speaking along to someone else's voice).

Eligibility Criteria

This trial is for individuals who have had a stroke and are experiencing nonfluent aphasia, which includes difficulty with speech production. Participants should be comfortable using a smartphone app at home for the treatment. There's no mention of specific exclusion criteria provided.

Inclusion Criteria

I am between 18 and 70 years old.

I have difficulty speaking due to a stroke in the left side of my brain.

I primarily speak English.

Exclusion Criteria

Persons with significant difficulties with language comprehension

English is not my first language.

Persons with concomitant cognitive disability

Treatment Details

Interventions

• Mirror Speech Entrainment (Behavioural Intervention)

Trial Overview The study is testing mirror speech entrainment, where participants speak along to their own digitally altered voice, against traditional methods using someone else's voice (with or without visual aid). The aim is to see if personalized voices can better improve language production in people with aphasia.

Participant Groups

Group I: Experiment 3: Mirror SE versus Traditional SE (Auditory-visual) Experimental Treatment 2 Interventions

This arm will investigate the effect of mirror speech entrainment in the auditory-visual modality versus traditional speech entrainment in the auditory-visual modality.

Group II: Experiment 2: Mirror SE versus Traditional SE (Auditory-only) Experimental Treatment 2 Interventions

This arm investigates the use of mirror speech entrainment using auditory only feedback and traditional speech entrainment using auditory only feedback.

Group III: Experiment 1: Feasibility Study Experimental Treatment 1 Intervention

Participants will receive two treatments sequentially: mirror speech entrainment using the auditory-only modality followed by mirror speech entrainment using the auditory-visual modality.

Who Is Running the Clinical Trial?

University of South Florida

Lead Sponsor

Trials

433

Recruited

198,000+