RFA for Thyroid Cancer

Overseen by Marius Stan, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Mayo Clinic

No Placebo Group

Trial Summary

What is the purpose of this trial?

This trial aims to test the effectiveness of using heat from radio waves to treat small thyroid cancers. It will focus on patients with small papillary thyroid carcinoma and will monitor changes in tumor size and other health indicators after treatment. Radiofrequency ablation (RFA) has been studied as a treatment for small papillary thyroid microcarcinomas, particularly in patients who are ineligible for surgery.

Research Team

Marius Stan, MD

Principal Investigator

Mayo Clinic

Eligibility Criteria

This trial is for adults with a small papillary thyroid carcinoma (less than 1.5 cm) that can be treated without surgery, as decided by their doctor and radiologist. It's not for those with widespread cancer, pregnant women, individuals who have difficult neck anatomy for RFA access, high anesthesia risk due to other illnesses, recent investigational drug use, substance abuse issues, blood clotting disorders or prior neck treatments.

Inclusion Criteria

I am 18 years old or older.

Diagnosed using fine needle aspiration (FNA) testing.

My scans show I can have RFA therapy with low risk.

Exclusion Criteria

My opposite side vocal cord is paralyzed.

Pregnancy

My cancer has spread to other parts of my body.

Treatment Details

Interventions

• RFA (Procedure)

Trial Overview The study is testing Radiofrequency Ablation (RFA), which uses heat to destroy cancer cells in treating papillary thyroid carcinoma. The goal is to see how effective RFA is at eliminating the tumor while minimizing risks.

Participant Groups

Group I: RFA Group Experimental Treatment 1 Intervention

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials

3,427

Recruited

3,221,000+

Dr. Gianrico Farrugia

Mayo Clinic

Chief Executive Officer since 2019

MD from University of Malta Medical School

Dr. Richard Afable

Mayo Clinic

Chief Medical Officer

MD from Loyola Stritch School of Medicine