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EVOO for Liver Transplant Recipients

N/A
Recruiting
Led By Danielle Kirkman
Research Sponsored by Virginia Commonwealth University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline at four weeks
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to study how a compound called TMAO affects the heart and blood vessels in patients who have had a liver transplant and are at risk for cardiovascular disease. The goal is to find ways

Who is the study for?
This trial is for adults over 18 who speak and understand English and have received a liver transplant. It aims to explore cardiovascular health in these patients.
What is being tested?
The study tests the effects of Extra Virgin Olive Oil (EVOO) on heart health in liver transplant recipients, focusing on TMAO levels—a factor linked to cardiovascular disease.
What are the potential side effects?
Potential side effects are not specified, but EVOO is generally considered safe with possible minor digestive issues or allergic reactions in rare cases.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from baseline at four weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline at four weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Serum TMAO
Secondary study objectives
Arterial hemodynamics changes
Conduit artery endothelial function changes
Diastolic Function change
+3 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: EVOO supplementationExperimental Treatment1 Intervention
50g/day, dietary supplementation Extra Virgin Olive Oil (EVOO)
Group II: Standard of CareActive Control1 Intervention
Standard of care control

Find a Location

Who is running the clinical trial?

Virginia Commonwealth UniversityLead Sponsor
719 Previous Clinical Trials
22,895,806 Total Patients Enrolled
Danielle KirkmanPrincipal InvestigatorVirginia Commonwealth University
1 Previous Clinical Trials
15 Total Patients Enrolled
~13 spots leftby Sep 2025
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