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Repetitive Transcranial Magnetic Stimulation Paired with Augmented Reality to Alter Concussion Symptoms

N/A
Waitlist Available
Research Sponsored by McMaster University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
* Male or female aged 18-65 years
* Diagnosis of mTBI according to the American Congress of Rehabilitation Medicine Diagnostic Criteria (Silverberg et al., 2023). All participants have diagnosis confirmed with Dr. Rathbone before enrollment.
Timeline
Screening 3 weeks
Treatment Varies
Follow Up before and after the 3-week intervention
Awards & highlights
No Placebo-Only Group

Summary

This study aims to determine whether the delivery of brain stimulation paired with a balance training task can improve symptoms of dizziness for individuals experiencing these symptoms due to concussion. The main questions it aims to answer are: * Does repetitive transcranial magnetic stimulation (rTMS) paired with balance training improve the symptoms of dizziness in individuals with persistent dizziness due to concussion? * Is the proposed rTMS and balance training protocol feasible in this population? Researchers will compare results from a sham rTMS group with those from a real rTMS group to see if any observed changes are from the placebo effect rather than the expected effects of real rTMS. Participants will receive pulses of rTMS to the area of the brain responsible for control of movement and then be asked to interact with digital objects using augmented reality glasses for 14 days over 3 weeks.

Eligible Conditions
  • Concussion
  • Dizziness
  • Vestibular Disorder

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~before and after the 3-week intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and before and after the 3-week intervention for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Dizziness Handicap Inventory (DHI)
Secondary study objectives
Activities-Specific Balance Confidence (ABC) Scale
Balance Error Scoring System (BESS)
Markers of inflammation
+3 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Real rTMSActive Control2 Interventions
Group II: Sham rTMSPlacebo Group2 Interventions

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Who is running the clinical trial?

McMaster UniversityLead Sponsor
918 Previous Clinical Trials
2,616,253 Total Patients Enrolled
1 Trials studying Dizziness
56 Patients Enrolled for Dizziness
Greenbank Concussion ClinicUNKNOWN
~27 spots leftby Dec 2025
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