CEUS for Spinal Cord Injury

Overseen By Brian F Saway, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Medical University of South Carolina

No Placebo Group

Trial Summary

What is the purpose of this trial?

This trial is testing a new imaging method called Contrast Enhanced Ultrasound (CEUS) to help doctors see blood flow changes in the spinal cord during surgery. It aims to help patients having surgery for chronic spinal cord pressure in the neck and upper back. The goal is to predict and prevent nerve damage by spotting blood flow issues early. CEUS has been used in various studies to visualize and assess blood flow in the spinal cord, including during surgery.

Research Team

Brian Saway, MD

Principal Investigator

Medical University of South Carolina

Stephen Kalhorn, MD

Principal Investigator

Medical University of South Carolina

Jessica Barley, PhD

Principal Investigator

Medical University of South Carolina

Eligibility Criteria

This trial is for adults aged 18-80 who are scheduled for posterior cervicothoracic decompression surgery to treat spinal cord compression. It's not suitable for those allergic to perflutren lipid microsphere or its components, pregnant individuals, patients with prior surgery at the same spot, or anyone unable to consent due to physical/cognitive reasons.

Inclusion Criteria

I am between 18 and 80 years old.

I am scheduled for spine surgery to treat my nerve and spinal cord condition.

Exclusion Criteria

Patients with known hypersensitivity to perflutren lipid microsphere or its components, such as polyethylene glycol (PEG)

Patients with known hypersensitivity to ultrasound contrast

Pregnancy

Treatment Details

Interventions

• Definity Perflutren Lipid Microsphere Ultrasound Contrast (Ultrasound Contrast Agent)

Trial Overview The study tests if a contrast agent called Definity Perflutren Lipid Microsphere Ultrasound Contrast can help visualize blood flow changes in the spine during surgery. The goal is to see if it predicts and shows recovery from spinal cord injuries better than current methods.

Participant Groups

Group I: Contrast Enhanced Ultrasound Arm Experimental Treatment 1 Intervention

Who Is Running the Clinical Trial?

Medical University of South Carolina

Lead Sponsor

Trials

994

Recruited

7,408,000+

South Carolina Spinal Cord Injury Research Fund

Collaborator

Trials

1

Recruited

20+