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McMaster University

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HAMILTON, Ontario L8N 3Z5
Global Leader in Asthma
Global Leader in Inflammatory Bowel Disease
Conducts research for Stroke
Conducts research for Blood Clot
Conducts research for Depression
258 reported clinical trials
41 medical researchers
Photo of McMaster University in HAMILTONPhoto of McMaster University in HAMILTONPhoto of McMaster University in HAMILTON

Summary

McMaster University is a medical facility located in HAMILTON, Ontario. This center is recognized for care of Asthma, Inflammatory Bowel Disease, Stroke, Blood Clot, Depression and other specialties. McMaster University is involved with conducting 258 clinical trials across 574 conditions. There are 41 research doctors associated with this hospital, such as Jeff S Healey, MD, Moin Khan, MD, Shamir Mehta, MD, and Richard Whitlock, MD.

Top PIs

Clinical Trials running at McMaster University

Depression
Hemophilia A
Osteoarthritis
Postpartum Depression
Hemophilia
Multiple Myeloma
Hemophilia B
Traumatic Brain Injury
Plasma Cell Neoplasms
Stroke
Image of trial facility.

Escitalopram + Brexpiprazole

for Depression

This is a study that will test a predictive biomarker algorithm based on results from a previous study. The goal of this study is to integrate clinical, imaging, EEG, and molecular data across 8 sites to predict treatment outcome for patients experiencing a major depressive episode (MDE).
Recruiting3 awards Phase 48 criteria
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Brexpiprazole

for Bipolar Disorder

Bipolar disorder (BD) is a frequent and lifelong recurrent mood disorder with treatment-resistant depressive episodes. Importantly, depressive symptoms and cognitive decline are major determinants of functionality and quality of life in this clinical population. There is robust evidence that individuals with BD have neurocognitive deficits (especially in memory and executive functioning domains) compared to the healthy population. These deficits are present in all mood states and can greatly affect patients' functional capacity, often more so than mood symptoms themselves. Many pharmacological treatments for BD adversely affect cognition, and those that are beneficial can be difficult to use. There is thus a pressing need to identify a safe, easy-to-use medication that can target both cognitive deficits and depressive symptoms in BD. It is expected that Brexpiprazole adjunctive treatment will be efficacious in treating BD type I and type II depression by improving mood symptoms, as well as cognitive capacity and global functioning, and that such changes will be accompanied by concurrent alterations in associated brain structures.
Recruiting2 awards Phase 313 criteria
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Cognitive Behavioral Therapy

for Postpartum Depression

The purpose of this study is to determine the effectiveness of an online 9-week group Cognitive Behavioural Therapy (CBT; a type of talking therapy) intervention that is co-led by public health nurses (PHNs) and individuals who have previously recovered (i.e., lay peers) from postpartum depression (PPD) for treating PPD when delivered in addition to treatment as usual (TAU) compared to TAU alone. The study will also assess the impact of the intervention on common comorbidities (anxiety) and complications (parenting stress, mother-infant relationship, social support, and infant temperament) of PPD and whether it is cost-effective.
Recruiting1 award N/A1 criteria

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Frequently asked questions

What kind of research happens at McMaster University?
McMaster University is a medical facility located in HAMILTON, Ontario. This center is recognized for care of Asthma, Inflammatory Bowel Disease, Stroke, Blood Clot, Depression and other specialties. McMaster University is involved with conducting 258 clinical trials across 574 conditions. There are 41 research doctors associated with this hospital, such as Jeff S Healey, MD, Moin Khan, MD, Shamir Mehta, MD, and Richard Whitlock, MD.