Vitamin
Vitamin D + Fish Oil for Health Improvement
This trial is studying whether taking daily dietary supplements of vitamin D3 or omega-3 fatty acids reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses.
Monoclonal Antibodies
Rituximab + Cyclosporine for Glomerulonephritis
This trial is testing the safety and effectiveness of combining two drugs to treat membranous nephropathy, a kidney disease associated with damage to the walls of the glomeruli. The first drug, rituximab, is an immunosuppressant that attempts to reduce the activity of the immune system. The second drug, cyclosporine, is a blood pressure lowering medication. The trial will last up to 2 years, and participants will have frequent blood and urine tests.
Anti-metabolites
ADI-001 for Lupus Nephritis
This trial is testing a new treatment for lupus nephritis in multiple centers. It will involve different stages like screening, treatment, and follow-up to find the appropriate dose and assess its safety and effectiveness
Popular Filters
Trials for Multiple Sclerosis Patients
Behavioral Intervention
Parent Group Education for Adolescent Type 1 Diabetes Transition
This trial will test if group education for parents of teens with type 1 diabetes helps improve the transition to adulthood. The study focuses on parents and aims to teach them how to better support their children in managing their diabetes. The goal is to see if these sessions can make a positive difference in the teens' health and self-management.
Stem Cell Therapy
Stem Cell Therapy for Chronic and Acute Conditions
This trial is testing stem cell therapy, which uses special cells to repair or replace damaged tissues. It targets patients with a range of acute and chronic conditions that may not respond well to traditional treatments. The therapy works by transforming stem cells into the needed cell types to improve organ and tissue function.
Anti-bacterial
Oral Antibiotics for Prosthetic Joint Infections
This trial is testing whether a 7-day course of an oral, prophylactic antibiotic can reduce the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk patient population.
Neurostimulation Device
VNS for Epilepsy
This trial is studying whether vagal nerve stimulation (VNS) for epilepsy affects bowel habits and the gut microbiome. VNS is a neurosurgical procedure where an impulse generator is placed near the vagus nerve in the neck.
Thromboxane A2 Receptor Antagonist
Oral Ifetroban for Scleroderma
This trial is testing ifetroban, an oral medication, in patients with severe forms of systemic sclerosis. The goal is to see if it can reduce inflammation and improve blood flow, potentially helping to manage their condition better.
Trials for Not A Treatment Study Patients
Behavioral Intervention
Parent Group Education for Adolescent Type 1 Diabetes Transition
This trial will test if group education for parents of teens with type 1 diabetes helps improve the transition to adulthood. The study focuses on parents and aims to teach them how to better support their children in managing their diabetes. The goal is to see if these sessions can make a positive difference in the teens' health and self-management.
Stem Cell Therapy
Stem Cell Therapy for Chronic and Acute Conditions
This trial is testing stem cell therapy, which uses special cells to repair or replace damaged tissues. It targets patients with a range of acute and chronic conditions that may not respond well to traditional treatments. The therapy works by transforming stem cells into the needed cell types to improve organ and tissue function.
Anti-bacterial
Oral Antibiotics for Prosthetic Joint Infections
This trial is testing whether a 7-day course of an oral, prophylactic antibiotic can reduce the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk patient population.
Neurostimulation Device
VNS for Epilepsy
This trial is studying whether vagal nerve stimulation (VNS) for epilepsy affects bowel habits and the gut microbiome. VNS is a neurosurgical procedure where an impulse generator is placed near the vagus nerve in the neck.
Thromboxane A2 Receptor Antagonist
Oral Ifetroban for Scleroderma
This trial is testing ifetroban, an oral medication, in patients with severe forms of systemic sclerosis. The goal is to see if it can reduce inflammation and improve blood flow, potentially helping to manage their condition better.
Stem Cell Transplant
Bone Marrow/Kidney Transplant for Blood Disorders & Chronic Kidney Disease
This trial is for a combined bone marrow and kidney transplant from a partially matched related donor to treat a blood disorder and kidney disease. The expectation is to have 10 people participate.
Trials With No Placebo
Behavioral Intervention
Parent Group Education for Adolescent Type 1 Diabetes Transition
This trial will test if group education for parents of teens with type 1 diabetes helps improve the transition to adulthood. The study focuses on parents and aims to teach them how to better support their children in managing their diabetes. The goal is to see if these sessions can make a positive difference in the teens' health and self-management.
Stem Cell Therapy
Stem Cell Therapy for Chronic and Acute Conditions
This trial is testing stem cell therapy, which uses special cells to repair or replace damaged tissues. It targets patients with a range of acute and chronic conditions that may not respond well to traditional treatments. The therapy works by transforming stem cells into the needed cell types to improve organ and tissue function.
Anti-bacterial
Oral Antibiotics for Prosthetic Joint Infections
This trial is testing whether a 7-day course of an oral, prophylactic antibiotic can reduce the incidence of periprosthetic joint infection and wound complications following primary total hip and knee arthroplasty in a high-risk patient population.
Neurostimulation Device
VNS for Epilepsy
This trial is studying whether vagal nerve stimulation (VNS) for epilepsy affects bowel habits and the gut microbiome. VNS is a neurosurgical procedure where an impulse generator is placed near the vagus nerve in the neck.
Stem Cell Transplant
Bone Marrow/Kidney Transplant for Blood Disorders & Chronic Kidney Disease
This trial is for a combined bone marrow and kidney transplant from a partially matched related donor to treat a blood disorder and kidney disease. The expectation is to have 10 people participate.
View More Related Trials
Frequently Asked Questions
Introduction to autoimmune diseases
What are the top hospitals conducting autoimmune diseases research?
When it comes to advancing the understanding and treatment of autoimmune diseases, several top hospitals are leading the way. In Boston, Massachusetts General Hospital is at the forefront with three ongoing clinical trials focused on autoimmune diseases. Throughout their history, they have conducted a total of seven such trials since their first recorded study in 2005. Meanwhile, in New york City, the Hospital for Special Surgery has made significant contributions as well. With three active autoimmune diseases trials and a record of three previous studies, this institution has been making strides since embarking on its first trial in 2017.
Heading over to Rochester's Mayo Clinic we find two ongoing clinical trials dedicated to autoimmune diseases alongside four previously conducted investigations dating back to their inaugural study in 2010. Similarly contributing towards advancements is Yale University situated in New Haven where two active clinical tests operate focusing solely on tackling these conditions; they share precedence with holding records of conducting three similar experiments ever since starting them from 2014.
Furthermore highlighting this list is the National Institutes of Health Clinical Center located in Bethesda where researchers are currently engaged with two active autoimmune disease clinical trials while having already accomplished five prior investigations concerning these illnesses; theirs can be traced back as far as completing initial research by kicking off earliest investigation around2009.
These remarkable institutions represent beacons of hope for individuals suffering from autoimmune diseases—conditions wherein the immune system mistakenly attacks healthy cells and tissues—that affect millions worldwide. Through their collective efforts in conducting ground-breaking clinical trials, they bring us closer to better treatments and ultimately seek cures that will transform lives for generations to come
Which are the best cities for autoimmune diseases clinical trials?
When it comes to clinical trials for autoimmune diseases, several cities in the United States are at the forefront of research. Boston, Massachusetts stands out with 10 active trials investigating treatments like Cohort B, Arm B2P: BNT162b2 and Nivolumab. New york City also offers promising opportunities with 10 ongoing studies focusing on interventions such as Nivolumab and Cohort B. Saint Louis, Missouri and Philadelphia, Pennsylvania follow closely behind with 8 and 6 active trials respectively, exploring options like Peresolimab and Oral Ifetroban. Lastly, Baltimore, Maryland contributes to the advancements in autoimmune disease research with its 5 ongoing trials involving Diamyd and Nivolumab among others. These cities offer individuals affected by autoimmune diseases access to cutting-edge clinical trials that pave the way for breakthroughs in treatment options and improve their quality of life.
Which are the top treatments for autoimmune diseases being explored in clinical trials?
Exciting developments in clinical trials are shedding light on potential breakthroughs in autoimmune disease treatment. Peresolimab, a newcomer to the field with one ongoing trial and one overall trial dedicated to autoimmune diseases since its debut in 2022, shows promise for future interventions. Another contender, Diamyd, is also making waves with its active involvement in one current trial and two all-time trials related to autoimmune diseases since it was first listed back in 2017. These innovative therapies offer hope for patients grappling with the challenges of managing autoimmune conditions.
What are the most recent clinical trials for autoimmune diseases?
In the ever-evolving landscape of autoimmune disease research, recent clinical trials have provided promising prospects for patients in need. One such trial focuses on the depletion of CD3/CD19 through autologous stem cell transplant, offering potential relief from these challenging conditions. Additionally, a 4 mg/kg cohort study has shown encouraging results across Phase 1 and Phase 2, shedding light on new avenues for treatment. The VCTX211 unit trial also displays great promise as it progresses through Phase 1 and Phase 2 stages. Furthermore, peresolimab's successful completion of its Phase 2 trial marks an important milestone in improving outcomes for individuals living with autoimmune diseases. Lastly, the ongoing Diamyd trial in its pivotal Phase 3 stage holds immense potential to transform therapeutic approaches within this field. These cutting-edge clinical trials showcase progress being made towards finding effective treatments that can make a meaningful difference in the lives of those affected by autoimmune diseases
What autoimmune diseases clinical trials were recently completed?
In the realm of autoimmune diseases, several recent clinical trials have concluded, offering insight and potential breakthroughs for patients. Notably, CRISPR Therapeutics AG completed a trial in January 2022 evaluating the VCTX210A unit's efficacy. In June 2021, Suzhou Connect Biopharmaceuticals finished their trial investigating CBP-307 as a treatment option. Furthermore, Bristol-Myers Squibb made progress with their branebrutinib study in January 2020. These significant advancements reflect the ongoing commitment to finding innovative solutions for individuals grappling with autoimmune disorders.