Hormone Therapy
IUD + Norethindrone Acetate for Endometriosis
This trial tests a combination of a hormone-releasing device placed in the uterus and a hormone pill to help young women with endometriosis manage pain and bleeding more effectively. The device releases a hormone to reduce pain, while the pill helps control bleeding and enhances the treatment's overall effectiveness.
Anti-infective Agent
Metronidazole for Postoperative Pain in Endometriosis
This trial is testing if taking the antibiotic metronidazole can reduce pain after endometriosis surgery in women aged 18-50. The antibiotic works by killing bacteria to prevent infections, which might help with pain relief.
Aromatase Inhibitor
Letrozole for Endometriosis Pain Management
This trial tests letrozole in women with endometriosis to see if it can improve their symptoms and egg quality. Letrozole works by lowering estrogen levels, potentially helping with symptom management. Letrozole has been used for a long time in various infertility treatments.
Dopamine Agonist
Cabergoline for Endometriosis
This trial is testing cabergoline, a medication that stops new blood vessels from forming, to see if it can reduce pain in adolescents and young women with endometriosis. Current treatments often don't work well or have too many side effects. Cabergoline may offer a safer, long-term solution by preventing the growth of new blood vessels needed for endometriosis to grow. Cabergoline has shown promise in early studies for treating chronic pain due to endometriosis.
NMDA Receptor Antagonist
Ketamine for Endometriosis Pain
This trial is testing whether a small dose of ketamine can help reduce pain after surgery in women with chronic pelvic pain from endometriosis. Ketamine works by blocking pain signals in the brain. Ketamine is an old anesthetic agent that has been explored for its efficacy in treating various pain conditions, including chronic pain and postoperative pain.
Popular Filters
Trials for Pelvic Pain Patients
Cannabinoid
CBD for Endometriosis Pain
This trial is testing CBD to see if it can help reduce pain and improve the quality of life for patients with endometriosis. The study will compare different doses of CBD over a few months. Researchers believe CBD may work by affecting the body's natural systems that control pain and inflammation. CBD has been shown to significantly improve pain intensity in some studies, although evidence quality is low due to high risk of bias and small sample sizes.
N/A
Hyivy Device for Endometriosis
This trial is testing the Hyivy device, which is designed to help reduce pelvic pain. The study focuses on people with endometriosis, a condition that causes significant pelvic pain. The device likely uses physical therapy methods to ease this pain.
Behavioural Intervention
Group Care Program for Endometriosis
This trial tests a program to help people with endometriosis-related pelvic pain reduce their pain and improve their quality of life. It includes peer support, education, mindfulness, and yoga.
Behavioral Intervention
Online Self-Management Program for Chronic Pelvic Pain
This trial aims to see if an online self-management program can help patients with Chronic Pelvic Pain feel better. The researchers believe that patients using the program will have less pain, better physical function, and
Trials for Chronic Prostatitis/Chronic Pelvic Pain Syndrome Patients
Cannabinoid
CBD for Endometriosis Pain
This trial is testing CBD to see if it can help reduce pain and improve the quality of life for patients with endometriosis. The study will compare different doses of CBD over a few months. Researchers believe CBD may work by affecting the body's natural systems that control pain and inflammation. CBD has been shown to significantly improve pain intensity in some studies, although evidence quality is low due to high risk of bias and small sample sizes.
N/A
Hyivy Device for Endometriosis
This trial is testing the Hyivy device, which is designed to help reduce pelvic pain. The study focuses on people with endometriosis, a condition that causes significant pelvic pain. The device likely uses physical therapy methods to ease this pain.
Behavioural Intervention
Group Care Program for Endometriosis
This trial tests a program to help people with endometriosis-related pelvic pain reduce their pain and improve their quality of life. It includes peer support, education, mindfulness, and yoga.
Photobiomodulation
Low-Level Laser Therapy for Endometriosis
This trial tests if light therapy inside the vaginal area can help women with endometriosis who have pain during sex. The light is believed to heal tissues and reduce pain by improving blood flow and reducing inflammation.
Phase 3 Trials
Cannabinoid
CBD for Endometriosis Pain
This trial is testing CBD to see if it can help reduce pain and improve the quality of life for patients with endometriosis. The study will compare different doses of CBD over a few months. Researchers believe CBD may work by affecting the body's natural systems that control pain and inflammation. CBD has been shown to significantly improve pain intensity in some studies, although evidence quality is low due to high risk of bias and small sample sizes.
GnRH Antagonist
Pre-IVF GnRH Antagonist for Endometriosis-related Infertility
This trial tests a pill that helps women with endometriosis who are undergoing IVF. These women often have lower success rates with IVF, and the pill helps manage hormone levels to improve their chances of having a baby.
Gonadotropin-Releasing Hormone (GnRH) Receptor Antagonist
Relugolix for Uterine Fibroids
This trial aims to understand how a 4-year treatment with a relugolix combination tablet affects bone mineral density in premenopausal women with heavy bleeding or endometriosis pain.
Trials With No Placebo
Behavioral Intervention
Online Program for Endometriosis Pain
This trial will test an online program called PelvicSense designed to help people with endometriosis manage their pain. Participants will follow the program remotely and continue their usual treatments. The study aims to see if this program can improve pain and other health outcomes.
Gonadotropin-Releasing Hormone (GnRH) Receptor Antagonist
Relugolix for Uterine Fibroids
This trial aims to understand how a 4-year treatment with a relugolix combination tablet affects bone mineral density in premenopausal women with heavy bleeding or endometriosis pain.
View More Related Trials
Frequently Asked Questions
Introduction to endometriosis
What are the top hospitals conducting endometriosis research?
When it comes to advancing the understanding and treatment of endometriosis, several top hospitals are leading the way. At The Pennsylvania State University in University Park, researchers are currently conducting two active clinical trials focused on this complex condition. With a total of two endometriosis trials under their belt since recording their first trial in 2018, they demonstrate a commitment to unraveling the mysteries surrounding endometriosis. Similarly, Penn State Health Milton S. Hershey Medical Center in Hershey also boasts two ongoing endometriosis trials and shares the same number of completed studies. Their contribution began with their first recorded trial in 2020.
Moving westward to Rochester, Minnesota, we find another renowned institution dedicated to tackling endometriosis: Mayo Clinic in Rochester. This prestigious medical center is actively involved in two clinical trials for this condition while having previously accomplished an equal number of investigations thus far; all these endeavors have materialized since initiating their inaugural trial in 2020.
The pursuit of advancements is not limited to large cities alone but extends even further across states like Arizona and California where Chandler and Canoga Park respectively house institutions making significant contributions as well. Chandler has taken up its role by conducting two active clinical tests related specifically to endometriosis; likewise, they have successfully carried out past experiments starting from just last year itself when they recorded their maiden investigation on this subject matter during 2021.The hospital at Canoga Park might exhibit a smaller scale than others mentioned here but does not lag behind regarding dedication towards combating this condition - boasting four previously held accomplishments alongside current involvement within ongoing double cases about Endrometriocosis ; marking its place using contributing research work since backtracking till2017.
These hospitals represent beacons of hope for individuals suffering from endometriosis worldwide as they strive towards better understanding and management strategies for this often misunderstood condition.
Which are the best cities for endometriosis clinical trials?
When it comes to endometriosis clinical trials, several cities have emerged as leaders in research and development. Birmingham, Alabama is at the forefront with 8 active trials focusing on treatments like Elagolix and Relugolix Combination Therapy. Houston, Texas closely follows with 7 ongoing studies exploring options such as Elagolix and OG-6219 Dose 3. Washington, District of Columbia also boasts 7 active trials investigating interventions like Transvaginal photobiomodulation and Plant-based Intervention Group. Additionally, Tampa, Florida offers individuals access to 6 active trials studying therapies including Elagolix and Linzagolix 75 mg. Lastly, Idaho Falls, Idaho provides opportunities for participation in 6 clinical trials involving treatments like Elagolix and Relugolix Combination Tablet or Therapy. These cities serve as hubs of cutting-edge research aimed at improving outcomes for those living with endometriosis.
Which are the top treatments for endometriosis being explored in clinical trials?
Endometriosis, a challenging condition for many women, is the focus of ongoing clinical trials exploring potential treatments. Leading the way is elagolix, currently being investigated in three active endometriosis trials and with an impressive track record of 13 all-time trials since its introduction in 2006. Also showing promise is transvaginal photobiomodulation, undergoing evaluation in one active trial and marking its debut on the scene in 2023. Atorvastatin brings another option to the table with one ongoing trial and two overall endometriosis studies since it was first listed in 2014. Finally, a plant-based intervention group has emerged as a contender with one active trial underway following its initial listing just last year in 2022. These groundbreaking clinical trials offer hope for improved management of this complex condition that affects countless women worldwide.
What are the most recent clinical trials for endometriosis?
Exciting advancements are being made in the field of endometriosis research, with recent clinical trials offering hope for improved treatment options. One promising trial involves the use of a Relugolix Combination Tablet, which is currently in Phase 3. This medication aims to provide relief from the symptoms associated with endometriosis and has shown positive results thus far. Another study focuses on utilizing 18F-fluorofuranylnorprogesterone PET/MRI imaging to better understand and diagnose endometriosis. Additionally, OG-6219 Dose 3 has entered Phase 2 trials as a potential therapeutic option for managing this condition. With these innovative approaches under investigation, there is reason to be optimistic about enhanced care for individuals living with endometriosis.
What endometriosis clinical trials were recently completed?
Recent clinical trials have made significant strides in the field of endometriosis research, bringing hope to those affected by this condition. In August 2020, the University of North carolina completed a trial investigating the potential of 18F-fluoroestradiol. Another noteworthy study was conducted by Bayer and concluded in July 2020, testing BAY1817080 as a potential treatment for endometriosis. Additionally, ObsEva SA wrapped up their trial on a linzagolix tablet in June 2019, while Northwestern University's investigation into ICG reached completion during the same month. These efforts demonstrate ongoing dedication within the medical community to find improved therapies for managing endometriosis and alleviating its impact on patients' lives.