Popular Trials
Biguanide
Metformin for Prediabetes
Recruiting2 awardsPhase 4
Phoenix, Arizona
This trial is testing whether metformin can lower the risk of death, heart attacks, and strokes in people with pre-diabetes and heart or blood vessel issues. Metformin is a drug that helps control blood sugar levels and has been used to treat type 2 diabetes mellitus for more than 60 years. The study involves patients who have pre-diabetes and existing heart or blood vessel problems, aiming to see if metformin can provide additional health benefits.
Air Filtration
Air Filtration for Heart Disease
Recruiting1 award6 criteria
Los Angeles, California
This trial tests if using special air filters in homes can help people with heart disease by cleaning the air they breathe. The goal is to see if reducing indoor air pollution can slow down the worsening of their heart condition.
ACL-inhibiting Regimen
Bempedoic Acid for HIV-Related Cardiovascular Disease
Recruiting0 awardsPhase 2
San Francisco, California
This trial will study the effect of Bempedoic acid (BA) on safety, arterial inflammation, lipids, inflammation, immune activation, cardiometabolic indices, and non-calcified plaque (NCP) in HIV-infected individuals aged ≥40 years with known CVD or 1 CVD risk factor.
Popular Filters
Trials for Peripheral Arterial Disease Patients
Microbiome Therapy
Fecal Microbial Transplant for Atherosclerosis
Recruiting0 awardsPhase 1
London, Ontario
"This trial aims to treat patients with unexplained severe atherosclerosis by giving them fecal transplants from patients with a Protected phenotype. The goal is to see how this affects the intestinal microbiome and
Anti-inflammatory
Colchicine for Cardiovascular Disease in Diabetes
Recruiting1 awardPhase 3
Ottawa, Ontario
This trial tests colchicine to see if it can reduce inflammation in blood vessel plaques in high-risk patients with diabetes or pre-diabetes who recently had a heart attack or stroke. The goal is to prevent future cardiovascular events by reducing plaque inflammation. Colchicine is an ancient drug with anti-inflammatory effects, historically used for conditions like gout and familial Mediterranean fever, and has shown promise in reducing cardiovascular events by targeting inflammation in blood vessel plaques.
Tissue Selective Estrogen Complex
Bazedoxifene + Estrogens for Atherosclerosis
Recruiting0 awardsPhase 2
Los Angeles, California
This trial is designed to test the effects of a tissue selective estrogen complex on the progression of subclinical atherosclerosis and cognitive decline in 360 postmenopausal women.
Trials for Peripheral Artery Disease Patients
Microbiome Therapy
Fecal Microbial Transplant for Atherosclerosis
Recruiting0 awardsPhase 1
London, Ontario
"This trial aims to treat patients with unexplained severe atherosclerosis by giving them fecal transplants from patients with a Protected phenotype. The goal is to see how this affects the intestinal microbiome and
Anti-inflammatory
Colchicine for Cardiovascular Disease in Diabetes
Recruiting1 awardPhase 3
Ottawa, Ontario
This trial tests colchicine to see if it can reduce inflammation in blood vessel plaques in high-risk patients with diabetes or pre-diabetes who recently had a heart attack or stroke. The goal is to prevent future cardiovascular events by reducing plaque inflammation. Colchicine is an ancient drug with anti-inflammatory effects, historically used for conditions like gout and familial Mediterranean fever, and has shown promise in reducing cardiovascular events by targeting inflammation in blood vessel plaques.
Tissue Selective Estrogen Complex
Bazedoxifene + Estrogens for Atherosclerosis
Recruiting0 awardsPhase 2
Los Angeles, California
This trial is designed to test the effects of a tissue selective estrogen complex on the progression of subclinical atherosclerosis and cognitive decline in 360 postmenopausal women.
Phase 3 Trials
Anti-inflammatory
Colchicine for Cardiovascular Disease in Diabetes
Recruiting1 awardPhase 3
Ottawa, Ontario
This trial tests colchicine to see if it can reduce inflammation in blood vessel plaques in high-risk patients with diabetes or pre-diabetes who recently had a heart attack or stroke. The goal is to prevent future cardiovascular events by reducing plaque inflammation. Colchicine is an ancient drug with anti-inflammatory effects, historically used for conditions like gout and familial Mediterranean fever, and has shown promise in reducing cardiovascular events by targeting inflammation in blood vessel plaques.
siRNA
Inclisiran for Cardiovascular Disease
Recruiting1 awardPhase 3
Montreal, Quebec
This trial is testing inclisiran, an injectable drug, on people with heart disease who are already on strong cholesterol-lowering medications. The goal is to see if inclisiran can further reduce the risk of heart attacks and strokes by lowering bad cholesterol levels. Participants will receive the injection periodically. Inclisiran works by significantly reducing bad cholesterol levels.
RNA-based Therapeutic
Inclisiran for Cardiovascular Disease
Recruiting1 awardPhase 3
Boston, Massachusetts
This trial tests inclisiran, a new injection to lower cholesterol, in people who have had heart attacks, strokes, or surgeries for blocked arteries. It works by blocking a protein that produces bad cholesterol.
Trials With No Placebo
Behavioural Intervention
Lifestyle Modification for Coronary Artery Disease
Recruiting1 award7 criteria
Houston, Texas
This trial is looking at whether a combined image-treatment regimen of PET + lifestyle modification and lipid-lowering drugs can improve cardiovascular risk score and potentially lower rate of death and other heart problems, compared to current standard of care.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.