Drug-Eluting Stent
Firehawk Stent for Coronary Artery Disease
Recruiting1 award8 criteria
Gilbert, Arizona
This trial is testing a new type of stent that releases a drug to keep heart arteries open in patients with certain types of heart disease. The goal is to see if it works as well as current treatments. Drug-eluting stents, which release drugs to prevent artery blockage, have shown promising results and are a major focus in cardiovascular medicine.
P2Y12 Inhibitor
Ticagrelor vs Clopidogrel for Coronary Artery Disease
Recruiting3 awardsPhase 4
Jacksonville, Florida
This trial is testing whether the drug ticagrelor is more effective than clopidogrel in reducing the risk of thrombotic events (blood clots) in patients who are also taking oral anticoagulants (blood thinners). A total of 63 patients will be enrolled and given either ticagrelor or clopidogrel. The trial will assess the pharmacodynamic effects of both drugs to determine which is more effective.
Device
Guided Physiologic Stenting for Coronary Artery Disease
Recruiting1 award4 criteria
Roslyn, New York
This trial compares two methods for guiding a heart procedure called PCI. It targets patients who need this procedure. One method uses X-ray images, and the other uses pressure measurements to help doctors see where to work during the procedure.
Popular Filters
Trials for CAD Patients
Surgery
Minimally Invasive vs. Conventional Heart Bypass for Coronary Artery Disease
Recruiting1 award4 criteria
Fresno, California
This trial compares a less invasive heart surgery to traditional open-chest surgery in patients with multiple blocked heart arteries. The goal is to see if the less invasive method helps patients recover quicker and improve their quality of life. The less invasive surgery was developed to allow adequate exposure and complete treatment from a small incision without the need for a heart-lung machine.
Genotype-Guided Smoking Cessation Therapy for Coronary Artery Disease
Recruiting1 award3 criteria
Saint Louis, Missouri
This trial tests if using genetic information to guide smoking cessation treatment can help patients with coronary artery disease quit smoking more effectively. Patients will receive either nicotine replacement therapy or counseling based on their genetic test results.
Procedure
Single vs Multiple Arterial Grafts for Heart Disease
Recruiting1 award1 criteria
Boulder, Colorado
This trial is testing whether using multiple arterial grafts (2+) is better than using a single arterial graft for coronary artery bypass surgery in terms of reducing the composite outcome of death from any cause, any stroke, post discharge myocardial infarction and/or repeat revascularization.
Procedure
Orbital Atherectomy vs. Angioplasty for Coronary Artery Disease
Recruiting1 award3 criteria
Birmingham, Alabama
This trial will compare a high-speed rotating device to remove hard calcium deposits with a traditional method for patients with severely calcified artery issues before placing special stents. The new device is designed to help treat these calcified areas.
Trials for Cardiovascular Disease Patients
Behavioural Intervention
Smartphone-Based Cardiac Rehab for Cardiovascular Disease
Recruiting1 award8 criteria
Atlanta, Georgia
This trial will test if a smartphone app & regular phone calls can help deliver better cardiac rehab to eligible veterans, resulting in better outcomes & decreased hospitalization rates.
Behavioural Intervention
Lifestyle Modification for Coronary Artery Disease
Recruiting1 award7 criteria
Houston, Texas
This trial is looking at whether a combined image-treatment regimen of PET + lifestyle modification and lipid-lowering drugs can improve cardiovascular risk score and potentially lower rate of death and other heart problems, compared to current standard of care.
Behavioral Intervention
Risk Reduction Program for Cardiovascular Disease
Recruiting1 award1 criteria
New York, New York
This trial is designed to better understand how to optimize risk factors for young patients with coronary artery disease, with a focus on gender differences. Patients will be part of a 6 month program that includes education, nutritional and exercise instruction, and psychological support. The goal is to improve quality of life and reduce risk factors.
Insomnia Therapy for Cardiovascular Disease Improvement
Recruiting1 award4 criteria
Indianapolis, Indiana
This trial will test if an updated insomnia treatment improves CVD factors & if this is due to improved sleep. 200 participants will get either the treatment or an active control. Results will be measured for CVD factors & sleep.
Balloon Catheter
Coronary Dilatation Catheter for Heart Disease
Recruiting1 award5 criteria
Miami, Florida
This trial will evaluate the safety and performance of a specific coronary dilatation catheter in treating Chronic Total Occlusion (CTO) lesions during a heart procedure. They plan to enroll 170 participants
Phase 3 Trials
Sodium-glucose cotransporter 2 (SGLT2) inhibitor
Canagliflozin for Heart Disease
Recruiting1 awardPhase 2 & 3
Ottawa, Ontario
This trial is a small study to see if a medication called canagliflozin can reduce inflammation in the arteries of patients with heart disease. They will compare the effects of canaglif
siRNA
Inclisiran + Statins for Coronary Artery Disease
Recruiting1 awardPhase 3
Beverly Hills, California
This trial is testing inclisiran, an injectable medication, to see if it can reduce plaque in heart arteries of patients with non-obstructive coronary artery disease who have not had previous heart events. Inclisiran works by lowering 'bad' cholesterol levels in the blood.
Water PET MPI for Coronary Heart Disease
Recruiting2 awardsPhase 3
Rochester, Minnesota
This trial will test a new PET imaging method to help diagnose coronary artery disease (CAD) in 182 participants at 10 sites in the US & Europe. The participants will receive two doses of a special imaging agent and have safety follow-ups.
Lipid-lowering Agent
Obicetrapib + Ezetimibe for Coronary Artery Disease
Recruiting1 awardPhase 3
Hialeah, Florida
This trial is testing a new medication combination in adults with high-risk cardiovascular disease who are not responding well to their current treatment. The study aims to see how the new medication affects coronary plaque and inflammation using
Trials With No Placebo
Surgery
Minimally Invasive vs. Conventional Heart Bypass for Coronary Artery Disease
Recruiting1 award4 criteria
Fresno, California
This trial compares a less invasive heart surgery to traditional open-chest surgery in patients with multiple blocked heart arteries. The goal is to see if the less invasive method helps patients recover quicker and improve their quality of life. The less invasive surgery was developed to allow adequate exposure and complete treatment from a small incision without the need for a heart-lung machine.
Genotype-Guided Smoking Cessation Therapy for Coronary Artery Disease
Recruiting1 award3 criteria
Saint Louis, Missouri
This trial tests if using genetic information to guide smoking cessation treatment can help patients with coronary artery disease quit smoking more effectively. Patients will receive either nicotine replacement therapy or counseling based on their genetic test results.
Procedure
Single vs Multiple Arterial Grafts for Heart Disease
Recruiting1 award1 criteria
Boulder, Colorado
This trial is testing whether using multiple arterial grafts (2+) is better than using a single arterial graft for coronary artery bypass surgery in terms of reducing the composite outcome of death from any cause, any stroke, post discharge myocardial infarction and/or repeat revascularization.
Procedure
Orbital Atherectomy vs. Angioplasty for Coronary Artery Disease
Recruiting1 award3 criteria
Birmingham, Alabama
This trial will compare a high-speed rotating device to remove hard calcium deposits with a traditional method for patients with severely calcified artery issues before placing special stents. The new device is designed to help treat these calcified areas.
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.