Sepsis Clinical Trials 2024

Sepsis research studies recruiting patients in 2024 need your help. Receive premium care & cutting edge treatments by enrolling in sepsis clinical trials today.

Popular Trials

Gasotransmitter

Inhaled Carbon Monoxide for ARDS

Recruiting0 awardsPhase 1

Boston, Massachusetts

This trial is testing a potential new treatment for sepsis-induced acute respiratory distress syndrome (ARDS) which could help improve safety and accuracy when compared to current methods.

Procedure

Thoracic Duct Drainage for Septic Shock

Recruiting1 award4 criteria

Philadelphia, Pennsylvania

This trial shows that early thoracic duct cannulation and external lymph drainage may help reduce pro-inflammatory cytokines in adult surgical intensive care patients.

TriVerity Test for Infections

Recruiting1 award1 criteria

Peoria, Illinois

This trial aims to enroll emergency department patients with suspected infection and rapid heart rate or fever who are initially placed in areas like waiting rooms or hallways. The study will compare patients treated with standard care before

Behavioural Intervention

Acupuncture for Sepsis

Recruiting0 awardsPhase 2

New York, New York

This trial is investigating whether acupuncture can help improve outcomes for people with sepsis. The study will compare real acupuncture to sham acupuncture, which is similar but uses different needles and targets different body sites.

Diuretic

Fluid Removal Protocol for Fluid Overload

Recruiting1 awardPhase 2

Toronto, Ontario

This trial is testing a new protocol to remove excess fluid from patients in the ICU. The goal is to see if patients will follow the protocol and if it will have any impact on their health.

Clinical Decision Support Algorithm

Decision Support for Antibiotic Selection in Sepsis

Recruiting1 award2 criteria

Mississauga, Ontario

This trial aims to help clinicians choose the right antibiotics for patients with sepsis, a severe infection. The goal is to balance between giving effective treatment and avoiding unnecessary antibiotics that can lead to resistance.

Popular Filters

Trials for Neonatal Sepsis Patients

Biguanide

Metformin for Sepsis-Induced AKI

Recruiting0 awardsPhase 2

Pittsburgh, Pennsylvania

This trial is testing if metformin, a diabetes drug, can help patients with severe infections who develop kidney problems. The drug works by activating a protein that protects the kidneys. Researchers want to see if it is safe and effective for these patients. Metformin has been studied for its effects on kidney function, with some studies suggesting potential harmful effects and others indicating possible protective benefits.

Machine Learning

Machine Learning Monitoring for Clinical Deterioration

Recruiting1 award2 criteria

Clearwater, Florida

This trial tests a tool that predicts when hospitalized patients may need intensive care or die, then offers guidance to help care teams intervene.

Behavioural Intervention

Precision Exercise Training for Sepsis

Recruiting1 award

Vancouver, British Columbia

This trial tests a personalized exercise program for sepsis survivors to see if it improves their ability to exercise and boosts their immune system. The program includes tailored strength and aerobic exercises over a few months.

Senolytic

Fisetin for Sepsis

Recruiting0 awardsPhase 2

Minneapolis, Minnesota

This trial will test if a drug called fisetin helps reduce the risk of sepsis in older people.

Cardiac Output Monitor

NICOM for Septic Shock

Recruiting1 award3 criteria

Minneapolis, Minnesota

This trial will test a non-invasive monitor to measure the need for fluid administration in sepsis patients, a more precise alternative to traditional single point readings.

Prehospital Sepsis Protocol for Sepsis

Recruiting1 award

Atlanta, Georgia

This trial will test if an emergency medical services (EMS) based sepsis screening and early warning protocol can improve the timing of sepsis care in the emergency department (ED).

Trials for Bacterial Blood Infection Patients

Biguanide

Metformin for Sepsis-Induced AKI

Recruiting0 awardsPhase 2

Pittsburgh, Pennsylvania

This trial is testing if metformin, a diabetes drug, can help patients with severe infections who develop kidney problems. The drug works by activating a protein that protects the kidneys. Researchers want to see if it is safe and effective for these patients. Metformin has been studied for its effects on kidney function, with some studies suggesting potential harmful effects and others indicating possible protective benefits.

Machine Learning

Machine Learning Monitoring for Clinical Deterioration

Recruiting1 award2 criteria

Clearwater, Florida

This trial tests a tool that predicts when hospitalized patients may need intensive care or die, then offers guidance to help care teams intervene.

Behavioural Intervention

Precision Exercise Training for Sepsis

Recruiting1 award

Vancouver, British Columbia

This trial tests a personalized exercise program for sepsis survivors to see if it improves their ability to exercise and boosts their immune system. The program includes tailored strength and aerobic exercises over a few months.

Senolytic

Fisetin for Sepsis

Recruiting0 awardsPhase 2

Minneapolis, Minnesota

This trial will test if a drug called fisetin helps reduce the risk of sepsis in older people.

Cardiac Output Monitor

NICOM for Septic Shock

Recruiting1 award3 criteria

Minneapolis, Minnesota

This trial will test a non-invasive monitor to measure the need for fluid administration in sepsis patients, a more precise alternative to traditional single point readings.

Prehospital Sepsis Protocol for Sepsis

Recruiting1 award

Atlanta, Georgia

This trial will test if an emergency medical services (EMS) based sepsis screening and early warning protocol can improve the timing of sepsis care in the emergency department (ED).

Phase 3 Trials

Vasopressor

Midodrine for Sepsis

Recruiting1 awardPhase 2 & 3

Rochester, Minnesota

This trial aims to see if giving Midodrine early can help people with sepsis need less medication to maintain their blood pressure. If successful, this could lead to shorter hospital stays, less time

Procedure

VBI-S for Septic Shock

Recruiting2 awardsPhase 3

Chandler, Arizona

This trial is testing a new treatment, VBI-S, to see if it can increase the blood pressure of patients with septic shock who have low blood volume.

Behavioural Intervention

Ultrasound-Guided Management for Septic Shock

Recruiting2 awardsPhase 3

London, Ontario

This trial aims to see if using venous excess ultrasound (VEXUS) to guide fluid management in patients with septic shock is possible. Septic shock is a severe condition where an infection leads

Fluid Resuscitation

Balanced Fluids for Pediatric Sepsis

Recruiting2 awardsPhase 3

Philadelphia, Pennsylvania

This trial is testing whether a balanced fluid solution is better than normal saline for children in septic shock, including whether it can help prevent kidney damage.

Hydrocortisone for Pediatric Septic Shock

Recruiting1 awardPhase 3

Tucson, Arizona

This trial will test if hydrocortisone can help children with septic shock who are not responding to other treatments.

Interleukin-1 Receptor Antagonist

Anakinra for Pediatric Multiple Organ Failure

Recruiting0 awardsPhase 2 & 3

Little Rock, Arkansas

This trial tests anakinra, a drug that reduces inflammation, in children with severe inflammation due to sepsis-induced organ failure. Anakinra works by blocking a protein that causes inflammation. It is widely used in treating Rheumatoid Arthritis and has shown potential in managing hyperinflammatory conditions like sepsis.

Trials With No Placebo

Machine Learning

Machine Learning Monitoring for Clinical Deterioration

Recruiting1 award2 criteria

Clearwater, Florida

This trial tests a tool that predicts when hospitalized patients may need intensive care or die, then offers guidance to help care teams intervene.

Behavioural Intervention

Precision Exercise Training for Sepsis

Recruiting1 award

Vancouver, British Columbia

This trial tests a personalized exercise program for sepsis survivors to see if it improves their ability to exercise and boosts their immune system. The program includes tailored strength and aerobic exercises over a few months.

Cardiac Output Monitor

NICOM for Septic Shock

Recruiting1 award3 criteria

Minneapolis, Minnesota

This trial will test a non-invasive monitor to measure the need for fluid administration in sepsis patients, a more precise alternative to traditional single point readings.

Prehospital Sepsis Protocol for Sepsis

Recruiting1 award

Atlanta, Georgia

This trial will test if an emergency medical services (EMS) based sepsis screening and early warning protocol can improve the timing of sepsis care in the emergency department (ED).

Enzyme

Intravenous DNase I for Sepsis

Recruiting1 awardPhase 1

Hamilton, Ontario

This trial is testing the safety and feasibility of giving a medication called IV DNase I to ICU patients with sepsis.

Behavioural Intervention

Nutrition Ecosystem for Post-Abdominal Surgery

Recruiting3 awardsPhase 4

Durham, North Carolina

This trial tests a detailed nutrition plan for patients after major abdominal surgery. It includes specialized feeding, assessing nutritional requirements, and monitoring health to ensure proper nutrition.

View More Related Trials

Frequently Asked Questions

Do I need insurance to participate in a trial?

Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).

Is there any support for travel costs?

Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.

Will I know what medication I am taking?

This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.

How long do clinical trials last?

Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.

Do you verify all the trials on your website?

All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.

How quickly will I hear back from a clinical trial?

Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.