Popular Trials
2'-FL Supplement for Inflammatory Bowel Disease
This trial tests 2'-FL, a sugar from breast milk, as a dietary supplement for young IBD patients in stable remission. It aims to boost good gut bacteria and improve gut health by increasing butyrate levels. 2'-FL, a human milk oligosaccharide, has been shown to promote the growth of beneficial gut bacteria and improve gut health in various studies.
Microbiome Modulator
FMT + Bezlotoxumab for IBD and C. Difficile Infection
This trial is testing whether FMT (fecal microbiota transplantation) plus bezlotoxumab is better than FMT plus placebo for treating IBD (inflammatory bowel disease) and CDI (clostridium difficile infection). Up to 150 patients will be enrolled, and they will be followed for 3 months.
Mesenchymal Stem Cell Therapy
ExoFlo for Ulcerative Colitis
This trial tests ExoFlo, a bone marrow cell-derived treatment, on patients with severe ulcerative colitis who haven't responded to other treatments. ExoFlo aims to reduce inflammation and heal the gut.
Monoclonal Antibodies
Infliximab Optimization for Crohn's Disease
This trial tests if using a computer program to decide infliximab doses is better and safer than standard dosing for patients with inflammatory bowel disease. The program helps doctors choose the best dose by looking at individual health details, aiming to keep the medication working well and prevent the disease from getting worse. Infliximab is commonly used to treat inflammatory bowel disease, and dose optimization has been shown to improve treatment outcomes.
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Trials for IBD Patients
Procedure
Ulcer Healing Analysis for Inflammatory Bowel Disease
This trial involves taking small pieces of tissue from the colon to study how ulcers heal. It includes patients with inflammatory bowel disease, arthritis, and healthy individuals to compare healing processes. Researchers will examine how genes work and how cells produce energy to understand healing.
Neurostimulation Device
VNS for Epilepsy
This trial is studying whether vagal nerve stimulation (VNS) for epilepsy affects bowel habits and the gut microbiome. VNS is a neurosurgical procedure where an impulse generator is placed near the vagus nerve in the neck.
Trials for Crohn's Disease Patients
Procedure
Ulcer Healing Analysis for Inflammatory Bowel Disease
This trial involves taking small pieces of tissue from the colon to study how ulcers heal. It includes patients with inflammatory bowel disease, arthritis, and healthy individuals to compare healing processes. Researchers will examine how genes work and how cells produce energy to understand healing.
Neurostimulation Device
VNS for Epilepsy
This trial is studying whether vagal nerve stimulation (VNS) for epilepsy affects bowel habits and the gut microbiome. VNS is a neurosurgical procedure where an impulse generator is placed near the vagus nerve in the neck.
Cannabinoid
Medical Cannabis for Chronic Pain
This trial will investigate if medical cannabis can effectively reduce pain and improve quality of life for patients with chronic conditions. The study will gather data through an online questionnaire about patients' use of cannabis and its effects. Medical cannabis interacts with the body's natural system to help manage pain and other symptoms. Medical cannabis has been increasingly studied and used as an alternative treatment for managing chronic pain, with numerous studies supporting its potential benefits.
Trials With No Placebo
Procedure
Ulcer Healing Analysis for Inflammatory Bowel Disease
This trial involves taking small pieces of tissue from the colon to study how ulcers heal. It includes patients with inflammatory bowel disease, arthritis, and healthy individuals to compare healing processes. Researchers will examine how genes work and how cells produce energy to understand healing.
Neurostimulation Device
VNS for Epilepsy
This trial is studying whether vagal nerve stimulation (VNS) for epilepsy affects bowel habits and the gut microbiome. VNS is a neurosurgical procedure where an impulse generator is placed near the vagus nerve in the neck.
Cannabinoid
Medical Cannabis for Chronic Pain
This trial will investigate if medical cannabis can effectively reduce pain and improve quality of life for patients with chronic conditions. The study will gather data through an online questionnaire about patients' use of cannabis and its effects. Medical cannabis interacts with the body's natural system to help manage pain and other symptoms. Medical cannabis has been increasingly studied and used as an alternative treatment for managing chronic pain, with numerous studies supporting its potential benefits.
Behavioral Intervention
Multimodal Intervention for Crohn's Disease Transition Care
This trial will test the effectiveness of a multimodal intervention focused on improving patient function, transition readiness and outcomes among AYA patients with IBD being cared for at pediatric centers in Canada. The intervention includes individualized assessment, a transition navigator, and virtual patient skills-building and education programs.
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Frequently Asked Questions
Introduction to inflammatory bowel disease
What are the top hospitals conducting inflammatory bowel disease research?
When it comes to advancing the treatment and understanding of inflammatory bowel disease (IBD), several top hospitals are leading the way. In Toronto, Canada, Mount Sinai Hospital is at the forefront with six active IBD trials and a total of 12 completed studies dedicated to this complex condition. Since its first recorded IBD trial in 2003, Mount Sinai has been unwavering in its commitment to finding innovative solutions for patients. Meanwhile, Massachusetts General Hospital in Boston has also made significant contributions to IBD research. With three ongoing clinical trials and eight past studies on record since their inaugural IBD trial in 2002, they continue to push boundaries and improve outcomes for those living with this challenging condition.
In Ottawa, Canada's Children's Hospital of Eastern Ontario plays a crucial role by conducting three active clinical trials related to IBD while having accomplished six prior investigations since their first recorded trial on this subject also back in 2002; their dedication towards pediatric patients is commendable.
Further adding itself into this esteemed list is Stanford University located in Palo Alto—the hub of Silicon Valley—where groundbreaking research meets innovation. Despite being relatively new compared to others on our list, Stanford recorded its first inflammatory bowel disease trial as recently as 2019 but already hosts three ongoing trials which offer hope for future breakthroughs.
Lastly yet no less important Brigham and Women's Hospital based out of Boston offers two current clinical tests concerning inflammatory bowel diseases while previously holding records up-to-date with onlythree experiments commencing from their initiation so far dating back four years ago until now starting from recording an investigation about such ailments upon beginning one experiment that took place around them during2017
These renowned hospitals demonstrate not only a dedication to treating individuals suffering from IBD but also an unwavering commitment towards improving patient care through cutting-edge research initiatives across North America.
Which are the best cities for inflammatory bowel disease clinical trials?
When it comes to clinical trials for inflammatory bowel disease, several cities emerge as leading hubs for research and advancements. Boston, Massachusetts stands out with 13 ongoing trials investigating treatments like Mirikizumab, Xylitol, and IPD Probe via TNIT. Toronto, Ontario follows closely behind with 7 active studies exploring interventions such as ta-IPAA and Nabilone Treatment. New york City also plays a significant role in IBD research with 7 trials focusing on therapies like Remote Monitoring and Mirikizumab. Additionally, Ottawa and Hamilton in Ontario each have 5 active trials examining various treatment options including Resistant Starch and Transition Coach Intervention. These cities offer individuals living with inflammatory bowel disease access to cutting-edge clinical studies that aim to improve their quality of life and bring new hope for effective treatments.
Which are the top treatments for inflammatory bowel disease being explored in clinical trials?
Clinical trials are underway to explore top treatments for inflammatory bowel disease (IBD), offering hope for patients battling this chronic condition. One such treatment is resistant starch, which is currently being studied in two active trials specifically targeting IBD. Another promising option being investigated is xylitol, with one ongoing trial dedicated to evaluating its effectiveness against IBD. Additionally, a plant-based fasting-mimicking diet has also caught the attention of researchers, with one active trial exploring its potential benefits for IBD patients. These innovative approaches hold promise for improving the lives of individuals living with IBD and may pave the way for future advancements in treatment options.
What are the most recent clinical trials for inflammatory bowel disease?
Exciting advancements in the realm of inflammatory bowel disease (IBD) are emerging through recent clinical trials. These studies offer promise for improved treatment options and management strategies. One such trial explores a novel dosing regimen, involving specific measurements administered at various timepoints, to assess its impact on IBD patients. Additionally, another trial delves into the effectiveness of methylprednisolone as a potential therapy for this chronic condition. Another study focuses on Group 1 treatments while yet another investigates MORF-057's efficacy in addressing IBD symptoms. Through these ongoing research efforts, we move closer to uncovering breakthroughs that will enhance the lives of those affected by inflammatory bowel disease.
What inflammatory bowel disease clinical trials were recently completed?
Recent advancements in the field of inflammatory bowel disease (IBD) have been fueled by several notable clinical trials. One such trial, sponsored by Stanford University, investigated the potential benefits of Vitamin d and concluded in July 2021. Additionally, Washington University School of Medicine completed a study on Infliximab, an important treatment option for IBD patients, in August 2020. These research endeavors highlight the ongoing efforts to uncover effective therapies that can alleviate symptoms and improve the quality of life for individuals living with IBD.