Popular Trials
Behavioural Intervention
Exercise + Protein + Electric Stimulation for Muscle Weakness
This trial will test whether a combination of physical rehabilitation, electrical stimulation, and high protein supplementation can prevent post-intensive care unit syndrome, a condition characterized by muscle loss, weakness, and cognitive decline.
Behavioural Intervention
Exercise Training for Sarcopenia
This trial aims to study how aging-related declines in physical, mental, and metabolic functions can be improved through exercise. The researchers will investigate the effectiveness of combining endurance and resistance training in older adults to better
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Trials With No Placebo
Procedure
TIPS Procedure for Liver Cirrhosis and Muscle Loss
This trial will test whether TIPS creation leads to improved muscle mass, body composition and muscle function within the first 12 months after the procedure compared to a control group without TIPS, and whether these changes improve liver disease outcomes in patients awaiting liver transplantation.
Behavioural Intervention
Protein-rich Diet and Exercise for Aging Muscles
This trial will compare the effects of consuming a healthy, protein-rich diet emphasizing lean beef, compared to a healthy, normal-protein, lower beef diet (control 1), and a healthy protein-rich, lower beef diet emphasizing non-beef/red meat protein (control 2) on resistance training-induced changes in muscle and tendon tissue size, strength, and quality in older women.
Frequently Asked Questions
Introduction to sarcopenia
What are the top hospitals conducting sarcopenia research?
In the battle against sarcopenia, a condition characterized by the loss of muscle mass and strength often associated with aging, several top hospitals are leading the charge in clinical trials. The U of Maryland, Baltimore Professional Schools IRB has emerged as a key player with two active sarcopenia trials and a total of two trials conducted thus far. Their commitment to understanding this condition began in 2015, marking their first recorded sarcopenia trial. Similarly, Beth Israel Deaconess Medical Center in Boston is making significant strides with two ongoing sarcopenia studies and a history of two completed trials since embarking on their research journey just recently in 2021.
Notably joining this mission is the Translational Research Institute for Metabolism and Diabetes in Orlando. With an equal number of active and all-time sarcopenia trials (two each), they have been investigating this condition since 2014—a testament to their dedication towards unraveling its complexities.
Further expanding geographical diversity within these efforts is the University of Oregon located in Eugene. Although having fewer active trials with just one currently underway, they hold great potential for advancing our knowledge about sarcopenia through their sole prior study initiated back in 2017.
Finally, breaking new ground on Canadian soil is Toronto's Goldring Center for High Performance Sport where they are actively conducting one cutting-edge sarcopenia trial—paving the way for breakthroughs that can positively impact future treatment options. Their inaugural contribution to research was documented only recently during 2023.
By pushing boundaries and exploring innovative approaches, these esteemed institutions offer hope to individuals living with or at risk of developing sarcopenia. Through collaboration between researchers across different locations, we inch closer toward discovering effective interventions that can combat muscle loss associated with aging—and ultimately improve quality of life for countless individuals around the world facing this challenge
Which are the best cities for sarcopenia clinical trials?
When it comes to sarcopenia clinical trials, several cities in the United States are at the forefront of research and development. Boston, Massachusetts leads the way with 6 active trials exploring interventions like exercise groups, low-soluble fiber diets, and LPCN 1148. Baltimore, Maryland closely follows with 5 ongoing studies focusing on interventions such as MRP+HPRO+NMES+UC and aerobic exercise training. Dallas, Texas also contributes to this field with 2 active trials investigating LPCN 1148 among other potential treatments. Other cities involved in sarcopenia clinical trials include Orlando, Florida and Aurora, Colorado. These cities offer individuals affected by sarcopenia access to cutting-edge research that paves the way for improved care options and a better quality of life.
Which are the top treatments for sarcopenia being explored in clinical trials?
Sarcopenia, the age-related decline in muscle mass and strength, is a condition that researchers are actively exploring for potential treatments. Among the top contenders are exercise training and exercise itself, with each having two active trials and an impressive track record of all-time sarcopenia trials—five for exercise training since 2011 and seventeen for exercise since 2009. Another intriguing option being investigated is a low-soluble fiber diet, which has one active trial thus far after its recent listing in 2023. As these clinical trials progress, they offer hope for combating sarcopenia and improving quality of life for individuals affected by this condition.
What are the most recent clinical trials for sarcopenia?
Exciting advancements are being made in the field of sarcopenia, with recent clinical trials offering promising possibilities for treatment. One such trial focuses on HB HIIT + CoQ10, a combination therapy that has entered Phase 3. This regimen aims to address the muscle loss associated with sarcopenia by incorporating high-intensity interval training (HIIT) and coenzyme Q10 (CoQ10). Another notable study is examining the effectiveness of zoledronic acid in combating sarcopenia during its Phase 4 stage. Additionally, MYMD-1 at a dosage of 600mg is currently under investigation in Phase 2 as a potential treatment option for this condition. Lastly, LPCN 1148 has shown potential benefits against sarcopenia and is progressing through its Phase 2 trial stages. These initiatives hold promise for individuals impacted by sarcopenia and offer hope for improved outcomes moving forward.
What sarcopenia clinical trials were recently completed?
Recently, several clinical trials focusing on sarcopenia have been completed, shedding light on potential strategies to combat this age-related condition. Notably, a trial sponsored by the University of Sao Paulo investigated the effects of resistance training combined with nutritional supplementation and concluded in November 2021. Another noteworthy study was conducted by the National Institute on Aging and examined the impact of hormone therapy in older adults; it reached completion in August 2021. These recent advancements highlight ongoing efforts to understand and address sarcopenia's complex nature, offering hope for improved treatments and interventions for individuals affected by this debilitating condition.