Dr. Armin A Zadeh, MD

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Johns Hopkins Hospital

Studies Coronary Artery Disease
Studies Cardiomyopathy
2 reported clinical trials
3 drugs studied

Affiliated Hospitals

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Johns Hopkins Hospital

Clinical Trials Armin A Zadeh, MD is currently running

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High-Resolution CT vs. Angiography

for Coronary Artery Disease

Cardiac catheterization with invasive coronary angiography is the gold standard for determining the presence or absence of significant coronary heart disease (CHD). However, cardiac catheterization is costly and, as an invasive procedure, it is associated with some risk of adverse events, rarely even stroke, myocardial infarction, or death. Recent advances in multi-detector computed tomography angiography (CTA) have allowed rapid, noninvasive coronary artery imaging in patients with suspected CHD. CTA generally yields high accuracy for identifying patients with CHD when compared to cardiac catheterization. However, diagnostic accuracy is reduced in the setting of severe coronary artery calcification and coronary stents due to its inferior spatial resolution compared to cardiac catheterization. Because high-risk patients often have severe coronary calcification or stents, the application of CTA has been particularly limited in this important patient group. Recently, an ultrahigh-resolution CT scanner was released which has shown promise to overcome the limitation of conventional CTA in the setting of severe coronary artery calcification or stents. This ultrahigh-resolution "precision" CT scanner (UHR-CT) contains detector rows with half the width than currently available systems (0.25 mm vs. 0.5 mm) resulting in approximately twice the spatial resolution. The purpose of this investigation is to test the hypothesis that high-resolution CTA is not inferior to the current standard of cardiac catheterization for identifying significant CHD in patients with high-risk characteristics, including severe coronary artery calcification and coronary stents. The investigators propose to enroll 50 patients over 24-30 months in this investigation as part of a multicenter study. Patients referred for cardiac catheterization with known CHD and suspected obstructive coronary artery stenosis will be included. All patients will undergo both cardiac catheterization and UHR-CT for determining significant CHD as defined by coronary functional assessment. The primary end point will be the diagnostic accuracy by area-under-curve (AUC) method for identifying patients with hemodynamically significant CHD.
Recruiting1 award N/A4 criteria
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PET/CT vs. Cardiac CT

for Coronary Artery Disease

Early detection of coronary atherosclerotic disease facilitates adequate prevention. The purpose of this study is to compare an assessment of coronary atherosclerotic disease burden by positron emission tomography / computed tomography (NaF-PET/CT) with those of conventional and ultra-high-resolution-CT (UHR-CT) in patients with suspected coronary artery disease. For this purpose, the investigators plan to include 33 patients with symptoms concerning for CAD who have been referred for cardiac CT testing.
Recruiting1 award N/A2 criteria

More about Armin A Zadeh, MD

Clinical Trial Related5 years of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Armin A Zadeh, MD has experience with
  • PET/CT
  • CT Angiography
  • Invasive Coronary Angiography

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Frequently asked questions

Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Armin A Zadeh, MD specialize in?
Armin A Zadeh, MD focuses on Coronary Artery Disease and Cardiomyopathy. In particular, much of their work with Coronary Artery Disease has involved treating patients, or patients who are undergoing treatment.
Is Armin A Zadeh, MD currently recruiting for clinical trials?
Yes, Armin A Zadeh, MD is currently recruiting for 2 clinical trials in Baltimore Maryland. If you're interested in participating, you should apply.
Are there any treatments that Armin A Zadeh, MD has studied deeply?
Yes, Armin A Zadeh, MD has studied treatments such as PET/CT, CT Angiography, Invasive Coronary Angiography.
What is the best way to schedule an appointment with Armin A Zadeh, MD?
Apply for one of the trials that Armin A Zadeh, MD is conducting.
What is the office address of Armin A Zadeh, MD?
The office of Armin A Zadeh, MD is located at: Johns Hopkins Hospital, Baltimore, Maryland 21287 United States. This is the address for their practice at the Johns Hopkins Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.