Carlos E. Vargas, M.D. - Doctors and ...

Dr. Carlos E. Vargas, M.D.

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Mayo Clinic in Arizona

Studies Prostate Cancer
Studies Breast Cancer
8 reported clinical trials
10 drugs studied

Affiliated Hospitals

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Mayo Clinic In Arizona

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Mayo Clinic

Clinical Trials Carlos E. Vargas, M.D. is currently running

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Hormone Therapy + Radiation

for Prostate Cancer

This phase II trial tests how well risk based de-escalated hormone therapy (i.e., fewer treatments) with radiation works in treating patients with prostate cancer. Androgen deprivation therapy (ADT), such as gonadotropin-releasing hormone analogs (LHRH) and abiraterone acetate (Zytiga), lower the amount of the male hormone, testosterone, made by the body. This may help kill or stop the growth of tumor cells that need testosterone to grow. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Research has shown that long-term ADT is beneficial for patients with high-risk prostate cancer. However, there are few studies that determine ADT treatment based on risk factors. Giving risk based de-escalated ADT with radiation therapy may be as effective as giving more ADT in treating high-risk prostate cancer.

Recruiting

1 award

Phase 2

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SBRT vs Hypofractionated Radiotherapy

for Recurrent Prostate Cancer

This phase III trial tests the side effects of stereotactic body radiation therapy (SBRT) compared to hypofractionated radiotherapy for treating patients with prostate adenocarcinoma that has come back after a period of improvement (recurrent) or that has spread from where it first started (primary site) to a limited number of sites (oligometastatic). SBRT is a type of external radiation therapy that uses special equipment to position a patient and precisely deliver radiation to tumors in the body (except the brain). The total dose of radiation is divided into smaller doses given over several days. This type of radiation therapy helps spare normal tissue. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumors cells and have fewer side effects. SBRT may work just as well as hypofractionated radiation therapy at treating patients with biochemically recurrent or oligometastatic prostate cancer, but with a shorter treatment time and possibly fewer side effects.

Recruiting

2 awards

Phase 3

More about Carlos E. Vargas, M.D.

Clinical Trial Related

6 years of experience running clinical trials · Led 8 trials as a Principal Investigator · 4 Active Clinical Trials

Treatments Carlos E. Vargas, M.D. has experience with

  • Hypofractionated Radiation Therapy
  • Radiation Therapy
  • Gonadotropin-releasing Hormone Analog
  • Proton Beam Radiation Therapy
  • X-ray Therapy
  • Biospecimen Collection

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