Dr. Christine Alewine, MD, PhD
Claim this profileNational Cancer Institute
Studies Pancreatic Cancer
Studies Skin Cancer
3 reported clinical trials
3 drugs studied
Area of expertise
1Pancreatic Cancer
Stage IV
Stage III
2Skin Cancer
Stage IV
Stage III
Affiliated Hospitals
Clinical Trials Christine Alewine, MD, PhD is currently running
ProAgio
for Advanced Pancreatic Cancer
This trial tests a new drug called ProAgio for safety and effectiveness in patients with advanced pancreatic cancer. Pancreatic cancer is very deadly, and current treatments are not very effective. ProAgio has shown good results in animal studies by treating the cancer and helping animals live longer.
Recruiting1 award Phase 112 criteria
Olaparib
for Pancreatic Cancer
Background: Pancreatic Acinar Cell Carcinoma (PACC) is a rare pancreatic tumor. People with PACC usually present with advanced disease, and their prognosis is poor. Researchers want to learn if a cancer drug called olaparib can help. Objective: To see if olaparib is an effective treatment for PACC. Eligibility: People aged 18 and older with PACC whose cancer did not respond to previous treatments or is not eligible for surgery. Design: Participants will be screened with the following: Medical history Physical exam Blood and urine tests Electrocardiogram (to test heart function) Computed tomography (CT) scans Pregnancy test (if needed) Tumor biopsy (if a sample is not available) Treatment will be given in 28-day cycles. Participants will take olaparib by mouth twice daily for each cycle. They will keep a medicine diary. They will receive treatment for up to 2 years. They may stop treatment early if their cancer gets worse or they have serious side effects. Participants will have study visits at the beginning of each cycle. At visits, they will repeat some screening tests. They will be asked about any changes in medicines they are taking and how they are feeling. They will have CT scans every 8 weeks starting in cycle 2. Participants will give blood samples for research. They may have optional tumor biopsies. Participants will have 2 follow-up visits in the 30 days after treatment ends or before they begin a new anti-cancer treatment. Then they will be contacted every 3 months by phone for 1 year. Participation will last for up to 3 years.
Recruiting1 award Phase 224 criteria
More about Christine Alewine, MD, PhD
Clinical Trial Related3 years of experience running clinical trials · Led 3 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Christine Alewine, MD, PhD has experience with
- Minnelide
- ProAgio
- Olaparib
Breakdown of trials Christine Alewine, MD, PhD has run
Pancreatic Carcinoma
Lung Carcinoma
Solid Tumor Cancers
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Christine Alewine, MD, PhD specialize in?
Christine Alewine, MD, PhD focuses on Pancreatic Cancer and Skin Cancer. In particular, much of their work with Pancreatic Cancer has involved Stage IV patients, or patients who are Stage III.
Is Christine Alewine, MD, PhD currently recruiting for clinical trials?
Yes, Christine Alewine, MD, PhD is currently recruiting for 2 clinical trials in Bethesda Maryland. If you're interested in participating, you should apply.
Are there any treatments that Christine Alewine, MD, PhD has studied deeply?
Yes, Christine Alewine, MD, PhD has studied treatments such as Minnelide, ProAgio, Olaparib.
What is the best way to schedule an appointment with Christine Alewine, MD, PhD?
Apply for one of the trials that Christine Alewine, MD, PhD is conducting.
What is the office address of Christine Alewine, MD, PhD?
The office of Christine Alewine, MD, PhD is located at: National Cancer Institute, Bethesda, Maryland 20892 United States. This is the address for their practice at the National Cancer Institute.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.