Dr. Dolores Grosso, DNP, CRNP
Claim this profileThomas Jefferson University
Studies Hematological Malignancies
Studies Multiple Myeloma
4 reported clinical trials
10 drugs studied
Area of expertise
1Hematological Malignancies
HLA positive
HLA negative
refractory anemia
2Multiple Myeloma
refractory anemia
refractory anemia with ring sideroblasts
isolated 5q-
Affiliated Hospitals
Clinical Trials Dolores Grosso, DNP, CRNP is currently running
Stem Cell Transplant
for Blood Cancers
This phase II trial studies the how well donor stem cell transplant works in treating patients with high risk hematologic malignancies. Giving total-body irradiation and chemotherapy before a donor stem cell transplant helps stop the growth of cells in the bone marrow, including normal blood-forming cells (stem cells) and cancer cells. It may also stop the patient's immune system from rejecting the donor's stem cells. When the healthy stem cells from a donor are infused into the patient they may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. The donated stem cells may also replace the patient's immune cells and help destroy any remaining cancer cells.
Recruiting3 awards Phase 2
Reduced-Intensity Conditioning
for Blood Cancers
This phase II clinical trial evaluates whether a modified modality of conditioning reduces treatment-related mortality (TRM) in patients who undergo a hematopoietic stem cell transplant (HSCT) for a hematological malignancy. HSCT is a curative therapy for many hematopoietic malignancies, however this regimen results in higher rates of TRM than other forms of treatment. In recent years, less intense conditioning regimens with radiation and chemotherapy prior to HSCT have been developed. Radiation therapy uses high energy sources to kill cancer cells and shrink tumors while chemotherapy drugs like fludarabine and cyclophosphamide work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This study evaluates whether a two-step approach with lower-intensity regimens of these treatments prior to HSCT reduces the rate of TRM.
Recruiting1 award Phase 28 criteria
More about Dolores Grosso, DNP, CRNP
Clinical Trial Related8 years of experience running clinical trials · Led 4 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Dolores Grosso, DNP, CRNP has experience with
- Cyclophosphamide
- Tacrolimus
- Total-Body Irradiation
- Mycophenolate Mofetil
- Fludarabine
- Allogeneic Hematopoietic Stem Cell Transplantation
Breakdown of trials Dolores Grosso, DNP, CRNP has run
Hematological Malignancies
Multiple Myeloma
Cancer
T-Lymphoblastic Leukemia/Lymphoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Dolores Grosso, DNP, CRNP specialize in?
Dolores Grosso, DNP, CRNP focuses on Hematological Malignancies and Multiple Myeloma. In particular, much of their work with Hematological Malignancies has involved HLA positive patients, or patients who are HLA negative.
Is Dolores Grosso, DNP, CRNP currently recruiting for clinical trials?
Yes, Dolores Grosso, DNP, CRNP is currently recruiting for 2 clinical trials in Philadelphia Pennsylvania. If you're interested in participating, you should apply.
Are there any treatments that Dolores Grosso, DNP, CRNP has studied deeply?
Yes, Dolores Grosso, DNP, CRNP has studied treatments such as Cyclophosphamide, Tacrolimus, Total-Body Irradiation.
What is the best way to schedule an appointment with Dolores Grosso, DNP, CRNP?
Apply for one of the trials that Dolores Grosso, DNP, CRNP is conducting.
What is the office address of Dolores Grosso, DNP, CRNP?
The office of Dolores Grosso, DNP, CRNP is located at: Thomas Jefferson University, Philadelphia, Pennsylvania 19107 United States. This is the address for their practice at the Thomas Jefferson University.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.