Dr. Mary McDermott, MD
Claim this profileNorthwestern University
Expert in Peripheral Artery Disease
Expert in Peripheral Arterial Disease
14 reported clinical trials
23 drugs studied
Area of expertise
1Peripheral Artery Disease
Global LeaderPAD
ABI
2Peripheral Arterial Disease
Global LeaderPAD
ABI
Affiliated Hospitals
Clinical Trials Mary McDermott, MD is currently running
Fisetin
for PAD
The investigators propose a pilot randomized trial to gather preliminary data to test the hypothesis that Fisetin will reduce abundance of senescent cells in blood, skeletal muscle, and both subcutaneous and inter muscular adipose tissue and improve 6-minute walk distance in 34 people with peripheral artery disease (PAD). the investigators will determine whether greater declines in abundance of cells with senescent markers are associated with greater improvement in 6-minute walk distance in people with peripheral artery disease. In exploratory analyses, the investigators will assess whether Fisetin reduces interleukin-6 (IL-6) and novel senescent markers in adipose tissue, muscle, and/or blood.
Recruiting0 awards Phase 22 criteria
Beetroot Juice
for Peripheral Arterial Disease
The BEET PAD Trial is a multi-centered double-blind randomized clinical trial designed to determine whether beetroot juice, compared to placebo, improves six-minute walk distance at four month follow-up in people with lower extremity peripheral artery disease (PAD). Investigators hypothesize that by simultaneously increasing lower extremity perfusion, gastrocnemius muscle mitochondrial activity, and myofiber health and regeneration, beetroot juice will significantly improve walking performance in people with PAD. The primary aim is to determine whether beetroot juice significantly improves six-minute walk distance at 4-month follow-up in people with PAD, compared to placebo. Preliminary evidence suggests that beetroot juice has both acute and chronic effects on walking performance in PAD. The primary outcome will measure the combined acute and chronic effect of beetroot juice (i.e. the maximal effect) on change in 6-minute walk at 4-month follow-up. In secondary aims, investigators will distinguish between acute and chronic effects of beetroot juice on six-minute walk and delineate biologic pathways by which beetroot juice improves walking performance in PAD, by measuring change in gastrocnemius muscle perfusion (MRI arterial spin labeling) and gastrocnemius muscle health. The trial will assess the durability of beetroot juice effects on six-minute walk. Nitrate in beetroot juice is metabolized to nitrite and subsequently to NO, attaining peak nitrite levels 2.5 hours after ingestion. The trial will determine whether a higher peak or a greater increase in plasma nitrite at 2.5 hours after beetroot juice consumption at baseline has a greater effect on six-minute walk at 4-month follow-up, compared to a lower peak or a smaller increase, respectively.
Recruiting0 awards N/A5 criteria
More about Mary McDermott, MD
Clinical Trial Related1 year of experience running clinical trials · Led 14 trials as a Principal Investigator · 11 Active Clinical TrialsTreatments Mary McDermott, MD has experience with
- Placebo
- Exercise
- Far Red Light Therapy
- Supervised Treadmill Exercise
- Unacylated Ghrelin
- Cocoa Flavanols
Breakdown of trials Mary McDermott, MD has run
Peripheral Artery Disease
Peripheral Arterial Disease
Vascular Disease
Peripheral Vascular Disease
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Mary McDermott, MD specialize in?
Mary McDermott, MD focuses on Peripheral Artery Disease and Peripheral Arterial Disease. In particular, much of their work with Peripheral Artery Disease has involved PAD patients, or patients who are ABI.
Is Mary McDermott, MD currently recruiting for clinical trials?
Yes, Mary McDermott, MD is currently recruiting for 11 clinical trials in Chicago Illinois. If you're interested in participating, you should apply.
Are there any treatments that Mary McDermott, MD has studied deeply?
Yes, Mary McDermott, MD has studied treatments such as Placebo, Exercise, Far Red Light Therapy.
What is the best way to schedule an appointment with Mary McDermott, MD?
Apply for one of the trials that Mary McDermott, MD is conducting.
What is the office address of Mary McDermott, MD?
The office of Mary McDermott, MD is located at: Northwestern University, Chicago, Illinois 60611 United States. This is the address for their practice at the Northwestern University.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.