Dr. Mrinalini Balki, MD
Claim this profileMount Sinai Hospital
Studies Postpartum Hemorrhage
Studies Bleeding
12 reported clinical trials
11 drugs studied
Affiliated Hospitals
Clinical Trials Mrinalini Balki, MD is currently running
Epidural Catheter
for Labor Pain
Epidural analgesia was introduced to the world of obstetrics in 1909 by Walter Stoeckel. Over the following 100 years it has developed to become the gold-standard for delivery of intra-partum analgesia, with between 60 and 75% of North American parturients receiving an epidural during their labor. Effective labor analgesia has been shown to improve maternal and fetal outcomes. One aspect of catheter insertion that has not been fully evaluated, and with very little recent work undertaken, is the optimal length of epidural catheter to be left in the epidural space. Dislodgement or displacement of epidural catheter remains a significant cause for failure with analgesia. Novel methods of fixation may further reduce the risk of catheter migration. Another factor is the direction of travel within the epidural space, only 13% of lumbar catheters remain uncoiled after insertion of more than 4 cm into the epidural space. Hypothesis: The investigators hypothesize that catheters inserted to 4 cm will have a lower rate of failure when compared to those inserted to 5 cm. Objective: This study aims to evaluate the difference in quality of labor analgesia delivered by epidural catheters inserted to either 4 or 5 cm into the epidural space. This study will be conducted as an interventional double-blinded randomised control trial to establish best practice.
Recruiting1 award N/A4 criteria
Ephedrine, Phenylephrine, and Norepinephrine
for Gestational Diabetes
The goal of this study is to learn about how medication that is used to help treat low blood pressure during a Cesarean delivery (CD) can cause changes to the uterine muscle tissue and its ability to contract, in patients with Type II and gestational diabetes. Spinal anesthesia administered during elective CD has been known to cause hypotension (low blood pressure) as a side effect during the procedure, and is prevented by administration of vasopressors (medication to raise blood pressure) by the anesthesiologist after the delivery of the baby. Vasopressors treat hypotension by interacting with receptors on blood vessels that increase blood pressure, which can also cause changes to uterine contractility. Inadequate uterine contraction after CD can expose mothers to postpartum hemorrhage (PPH), with diabetic patients displaying a 2.5-times higher risk of PPH. It is important to understand how vasopressor(s) might affect the uterine contractility of women with Type II and gestational diabetes. Since medication to contract the uterus is also routinely administered at delivery, it is important to study the effect of these drugs in combination. The purpose of this study is to compare uterine contractility patterns and receptor distribution in women with type II and gestational diabetic and control term pregnant patients with administration of vasopressors. This will be done using small uterine tissue samples taken from the incision site following CD, which will then be used for experiments in the laboratory.
Recruiting1 award N/A
More about Mrinalini Balki, MD
Clinical Trial Related3 years of experience running clinical trials · Led 12 trials as a Principal Investigator · 7 Active Clinical TrialsTreatments Mrinalini Balki, MD has experience with
- Oxytocin
- Ephedrine
- Phenylephrine
- Norepinephrine
- Carbetocin
- Vasopressin
Breakdown of trials Mrinalini Balki, MD has run
Postpartum Hemorrhage
Bleeding
Obesity
Low Blood Pressure
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Mrinalini Balki, MD specialize in?
Mrinalini Balki, MD focuses on Postpartum Hemorrhage and Bleeding. In particular, much of their work with Postpartum Hemorrhage has involved treating patients, or patients who are undergoing treatment.
Is Mrinalini Balki, MD currently recruiting for clinical trials?
Yes, Mrinalini Balki, MD is currently recruiting for 7 clinical trials in Toronto Ontario. If you're interested in participating, you should apply.
Are there any treatments that Mrinalini Balki, MD has studied deeply?
Yes, Mrinalini Balki, MD has studied treatments such as Oxytocin, Ephedrine, Phenylephrine.
What is the best way to schedule an appointment with Mrinalini Balki, MD?
Apply for one of the trials that Mrinalini Balki, MD is conducting.
What is the office address of Mrinalini Balki, MD?
The office of Mrinalini Balki, MD is located at: Mount Sinai Hospital, Toronto, Ontario M5G1X5 Canada. This is the address for their practice at the Mount Sinai Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.