Dr. Ralph Salloum, MD
Claim this profileNationwide Children's Hospital
Studies Brain Tumor
Studies Medulloblastoma
3 reported clinical trials
5 drugs studied
Affiliated Hospitals
Clinical Trials Ralph Salloum, MD is currently running
Savolitinib
for Brain Tumors
This phase I trial studies the side effects and best dose of volitinib in treating patients with primary central nervous system (CNS) tumors that have come back (recurrent) or does not respond to treatment (refractory). Volitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Recruiting1 award Phase 1
Dabrafenib + Trametinib + Hydroxychloroquine
for Brain Tumor
This phase I/II trial is designed to study the side effects, best dose and efficacy of adding hydroxychloroquine to dabrafenib and/or trametinib in children with low grade or high grade brain tumors previously treated with similar drugs that did not respond completely (progressive) or tumors that came back while receiving a similar agent (recurrent). Patients must also have specific genetic mutations including BRAF V600 mutations or BRAF fusion/duplication, with or without neurofibromatosis type 1. Neurofibromatosis type 1 is an inherited genetic condition that causes tumors to grow on nerve tissue. Hydroxychloroquine, works in different ways to stop the growth of tumor cells by killing the cells or stopping them from dividing. Trametinib and dabrafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving hydroxychloroquine with trametinib and/or dabrafenib may lower the chance of brain tumors growing or spreading compared to usual treatments.
Recruiting1 award Phase 1 & 216 criteria
More about Ralph Salloum, MD
Clinical Trial Related6 years of experience running clinical trials · Led 3 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Ralph Salloum, MD has experience with
- Dabrafenib
- Trametinib
- Hydroxychloroquine
- CX-4945
- Savolitinib
Breakdown of trials Ralph Salloum, MD has run
Medulloblastoma
Neurofibromatosis
Low Grade Glioma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Ralph Salloum, MD specialize in?
Ralph Salloum, MD focuses on Brain Tumor and Medulloblastoma. In particular, much of their work with Brain Tumor has involved MET positive patients, or patients who are undergoing treatment.
Is Ralph Salloum, MD currently recruiting for clinical trials?
Yes, Ralph Salloum, MD is currently recruiting for 2 clinical trials in Columbus Ohio. If you're interested in participating, you should apply.
Are there any treatments that Ralph Salloum, MD has studied deeply?
Yes, Ralph Salloum, MD has studied treatments such as Dabrafenib, Trametinib, Hydroxychloroquine.
What is the best way to schedule an appointment with Ralph Salloum, MD?
Apply for one of the trials that Ralph Salloum, MD is conducting.
What is the office address of Ralph Salloum, MD?
The office of Ralph Salloum, MD is located at: Nationwide Children's Hospital, Columbus, Ohio 43205 United States. This is the address for their practice at the Nationwide Children's Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.