Reem Karmali, MD, MS: Robert H. Lurie ...

Dr. Reem Karmali

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Northwestern University

Studies B-Cell Lymphoma
Studies Lymphoma
16 reported clinical trials
31 drugs studied

Area of expertise

1

B-Cell Lymphoma

Reem Karmali has run 10 trials for B-Cell Lymphoma. Some of their research focus areas include:

MYC positive
BCL2 positive
BCL6 positive
2

Lymphoma

Reem Karmali has run 9 trials for Lymphoma. Some of their research focus areas include:

MYC positive
BCL2 positive
BCL6 positive

Affiliated Hospitals

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Northwestern University

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Northwestern Memorial Hospital

Clinical Trials Reem Karmali is currently running

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Pembrolizumab + Tazemetostat

for Non-Hodgkin's Lymphoma

This phase II trial tests how well pembrolizumab and tazemetostat work to treat patients who have received autologous stem cell transplantation (ASCT) or chimeric antigen receptor (CAR) T cell therapy for aggressive non hodgkins lymphoma. A monoclonal antibody, such as pembrolizumab, is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Tazemetostat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving pembrolizumab and tazemetostat may work better to treat patients who have received ASCT or CAR-T cell therapy for aggressive non hodgkins lymphoma.

Recruiting

1 award

Phase 2

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Epcoritamab + Lenalidomide

for B-Cell Lymphoma

This phase II trial tests how well the combination of epcoritamab and lenalidomide work in treating patients with immunodeficiency-related large B-cell lymphoma that does not respond to treatment (refractory) or that has come back after a period of improvement (relapsed). Epcoritamab is an immunotherapy that engages T-cells in the immune system to help redirect their killing effects against lymphoma cells. Lenalidomide can modulate the immune system to enhance killing effects of lymphoma by the immune system as well. Giving patients a combination of epcoritamab and lenalidomide may work better in treating refractory or relapsed immunodeficiency-related large B-cell lymphoma.

Recruiting

1 award

Phase 2

6 criteria

More about Reem Karmali

Clinical Trial Related

1 year of experience running clinical trials · Led 16 trials as a Principal Investigator · 4 Active Clinical Trials

Treatments Reem Karmali has experience with

  • Rituximab
  • Cyclophosphamide
  • Nivolumab
  • Lenalidomide
  • Pembrolizumab
  • Prednisone

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