Dr. Rodney Breau, MD
Claim this profileThe Ottawa Hospital
Studies Prostate Cancer
Studies Bladder Cancer
6 reported clinical trials
14 drugs studied
Area of expertise
1Prostate Cancer
Stage II
Stage I
Stage IV
2Bladder Cancer
Affiliated Hospitals
Clinical Trials Rodney Breau, MD is currently running
Genomic Biomarker-Selected Therapy
for Prostate Cancer
The objective of this study is to see if providing an appropriate therapy based on the genomic testing of prostate tumour tissue will result in an improved clinical response. Each participant will be treated with 8 weeks of a luteinizing hormone-releasing hormone agonist (LHRHa) plus apalutamide (APA) while genome sequence characterization is being done. Participants with biopsy specimens deemed unevaluable for genomic testing will remain on LHRHa plus APA for an additional 16 weeks. Participants with evaluable tissue will be assigned to one of the open-label sub-studies on the basis of genomic profiling results. Within each group, they will be randomized to a specific treatment arm either LHRHa plus APA alone or adding abiraterone acetate and prednisone, docetaxel or niraparib. The study will evaluate the response rate and outcomes after radical prostatectomy in each arm of the trial.
Recruiting1 award Phase 210 criteria
Chemotherapy
for Bladder Cancer
Upper tract urothelial cancer (UTUC) is cancer in the lining of the kidney or ureter (the tube that drains the kidney). This type of cancer is rare and as a result, there are only a few studies that have looked at it. Standard of care for UTUC would be surgery followed by chemotherapy (adjuvant chemotherapy). However, we know from studies that have looked at cancer of the lining of the bladder, which is a similar cancer in many ways, that treating people with chemotherapy before surgery (neoadjuvant chemotherapy) can lead to longer survival compared to the standard of care. There are no studies to show this in UTUC. Neoadjuvant chemotherapy is thought to help improve survival by treating any cancer that may have spread from the original tumour but that is not visible yet on scans. This study would be the first clinical trial in Canada to evaluate the use of chemotherapy before surgery in this disease setting. Since UTUC is rare, the purpose of this study is to determine if it is possible to enrol enough patients to a trial looking at the use of chemotherapy before surgery.
Recruiting2 awards Phase 3
More about Rodney Breau, MD
Clinical Trial Related2 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Rodney Breau, MD has experience with
- Placebo
- Whole-body FDG PET-CT
- Metformin
- Tranexamic Acid
- Gemcitabine
- Carboplatin
Breakdown of trials Rodney Breau, MD has run
Prostate Cancer
Transitional Cell Carcinoma
Noncardiac Surgery
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Rodney Breau, MD specialize in?
Rodney Breau, MD focuses on Prostate Cancer and Bladder Cancer. In particular, much of their work with Prostate Cancer has involved Stage II patients, or patients who are Stage I.
Is Rodney Breau, MD currently recruiting for clinical trials?
Yes, Rodney Breau, MD is currently recruiting for 3 clinical trials in Ottawa Ontario. If you're interested in participating, you should apply.
Are there any treatments that Rodney Breau, MD has studied deeply?
Yes, Rodney Breau, MD has studied treatments such as Placebo, Whole-body FDG PET-CT, Metformin.
What is the best way to schedule an appointment with Rodney Breau, MD?
Apply for one of the trials that Rodney Breau, MD is conducting.
What is the office address of Rodney Breau, MD?
The office of Rodney Breau, MD is located at: The Ottawa Hospital, Ottawa, Ontario K1H8L6 Canada. This is the address for their practice at the The Ottawa Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.