Dr. Ronald A Lehman, M.D.
Claim this profileColumbia University Irving Medical Center
Studies Bleeding
Studies Spinal Injury
2 reported clinical trials
7 drugs studied
Affiliated Hospitals
Clinical Trials Ronald A Lehman, M.D. is currently running
Tranexamic Acid
for Spinal Injury
This study is designed to evaluate the efficacy of topical tranexamic acid to reduce perioperative blood loss, reduction in postoperative drain output and allogenic transfusion requirements. The proposed study will be a prospective, randomized, double-blind (subject, surgeons, investigators, research coordinators) placebo-controlled study. Patients following high energy trauma who have sustained thoracic or lumbar spine fractures, dislocations or ligamentous injury with resultant instability requiring posterior spinal fusion will be enrolled for this study. Furthermore, patients undergoing elective complex deformity surgery will also be enrolled. Both populations of patients will be randomized into two groups. Group I will receive standard of care operative fixation with topical tranexamic acid intervention (test); Group II will receive standard of care operative fixation with normal saline (placebo) intervention. This study will have a 2-year follow-up and will consist of three periods: screening/enrollment phase up to 21 days from the day of injury to the day of randomization and operative intervention, an inpatient data collection period for 4 days postoperative, and then a follow-up period for 2-years postoperative (visits occurring at 2 week, 16 week, 1 year, and 2 year) time points.
Recruiting0 awards Phase 2 & 3
Spinal Cord Stimulation
for Spinal Cord Injury
Spinal cord associative plasticity (SCAP) is a combined cortical and spinal electrical stimulation technique developed to induce recovery of arm and hand function in spinal cord injury. The proposed study will advance understanding of SCAP, which is critical to its effective translation to human therapy. The purpose of the study is to: 1. Determine whether signaling through the spinal cord to the muscles can be strengthened by electrical stimulation. 2. Improve our understanding of the spinal cord and how it produces movement. 3. Determine whether spinal surgery to relieve pressure on the spinal cord can improve its function. Aim 1 is designed to advance mechanistic understanding of spinal cord associative plasticity (SCAP). Aim 2 will determine whether SCAP increases spinal cord excitability after the period of repetitive pairing. In rats, SCAP augments muscle activation for hours after just 5 minutes of paired stimuli. Whereas Aims 1 and 2 focused on the effects of paired stimulation in the context of uninjured spinal cord, Aim 3 assesses whether paired stimulation can be effective across injured cord segments. Aim 3 will incorporate the experiments from Aim 1 and 2 but in people with SCI, either traumatic or pre-operative patients with myelopathy in non-invasive experiments, or targeting myelopathic segments in intraoperative segments.
Recruiting1 award Phase < 19 criteria
More about Ronald A Lehman, M.D.
Clinical Trial Related4 years of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Ronald A Lehman, M.D. has experience with
- Placebo
- Tranexamic Acid
- Intraoperative Pairing Of Cortical And Spinal Stimulation
- Intraoperative Repeated Pairing Of Cortical And Spinal Stimulation (SCAP)
- Intraoperative Repeated Pairing Of Cortical And Spinal Stimulation (SCAP) At Or Below Myelopathic Region
- Non-invasive Pairing Of Cortical And Spinal Stimulation
Breakdown of trials Ronald A Lehman, M.D. has run
Spinal Injury
Scoliosis
Spinal Cord Injury
Dorsal Column Myelopathy
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Ronald A Lehman, M.D. specialize in?
Ronald A Lehman, M.D. focuses on Bleeding and Spinal Injury. In particular, much of their work with Bleeding has involved treating patients, or patients who are undergoing treatment.
Is Ronald A Lehman, M.D. currently recruiting for clinical trials?
Yes, Ronald A Lehman, M.D. is currently recruiting for 2 clinical trials in New York New York. If you're interested in participating, you should apply.
Are there any treatments that Ronald A Lehman, M.D. has studied deeply?
Yes, Ronald A Lehman, M.D. has studied treatments such as Placebo, Tranexamic Acid, Intraoperative pairing of cortical and spinal stimulation.
What is the best way to schedule an appointment with Ronald A Lehman, M.D.?
Apply for one of the trials that Ronald A Lehman, M.D. is conducting.
What is the office address of Ronald A Lehman, M.D.?
The office of Ronald A Lehman, M.D. is located at: Columbia University Irving Medical Center, New York, New York 10032 United States. This is the address for their practice at the Columbia University Irving Medical Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.