Samuel Chao, MD | Cleveland Clinic

Dr. Samuel T. Chao, MD

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Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center

Studies Brain Tumor
Studies Protoplasmic Astrocytoma
5 reported clinical trials
10 drugs studied

Area of expertise

1

Brain Tumor

Samuel T. Chao, MD has run 4 trials for Brain Tumor. Some of their research focus areas include:

IDH positive
1p/19q co-deletion positive
Stage IV
2

Protoplasmic Astrocytoma

Samuel T. Chao, MD has run 2 trials for Protoplasmic Astrocytoma. Some of their research focus areas include:

IDH positive
1p/19q co-deletion positive
1p/19q loss positive

Affiliated Hospitals

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Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center

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Cleveland Clinic Taussig Cancer Center

Clinical Trials Samuel T. Chao, MD is currently running

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MRF + IVIM MRI

for Brain Cancer

The purpose of this study is to discover the potential convenience and ease of using a Magnetic Resonance Imaging (MRI) technique, named Magnetic Resonance Fingerprinting (or MRF), to achieve high-quality images within a short scan time of 5 min for viewing the entire brain. This is an advanced quantitative assessment of brain tissues. This method is being applied with IVIM MRI to be able to tell the difference between a brain with radiation necrosis and a brain with tumor recurrence. Participants will consist of individuals who have received radiation therapy in the past and were diagnosed with radiation necrosis, individuals with recurrent tumors, individuals with previously untreated tumors, and healthy individuals who have no brain diseases and have not had radiation treatment to the brain. Participants will undergo an MRI scan at a one-time research study visit; no extra tests or procedures will be required for this research study. The primary objectives of this study are: * To demonstrate the clinical feasibility of combining MRF with state-of-the-art parallel imaging techniques to achieve high-resolution quantitative imaging within a reasonable scan time of 5 min for whole brain coverage. * To apply the developed quantitative approach in combination with IVIM MRI for differentiation of tumor recurrence and radiation necrosis. * To investigate the effect of radiation dose on the development of radiation necrosis and tumor recurrence.

Recruiting

1 award

N/A

8 criteria

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Spine Stereotactic Radiosurgery

for Spinal Cancer

Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away from normal tissue. One of the side effects of spine SRS is the development of vertebral compression fractures, many of which are not painful. The goal of this study is to compare the effects, good and/or bad, of spine SRS given in 1 or 2 treatments. Our main goal is to find out which approach will reduce the chances of developing vertebral compression fractures.

Recruiting

1 award

Phase 2

14 criteria

More about Samuel T. Chao, MD

Clinical Trial Related

1 year of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Samuel T. Chao, MD has experience with

  • Spine SRS In 1 Fraction
  • Spine SRS In 2 Fraction
  • Stereotactic Radiosurgery
  • MRF In Conjunction With IVIM MRI
  • CCNU
  • Radiotherapy

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