Dr. Sanjeev Kumar, MD

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Centre for Addiction and Mental Health

Studies Alzheimer's Disease
Studies Dementia
4 reported clinical trials
4 drugs studied

Affiliated Hospitals

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Centre For Addiction And Mental Health

Clinical Trials Sanjeev Kumar, MD is currently running

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tDCS

for Alzheimer's Dementia

Agitation and aggression impose a tremendous burden on the individuals living with dementia, their families, caregivers, and healthcare systems. Neuropsychiatric symptoms of dementia (NPS) affect up to 80% of patients with Alzheimer's dementia (AD). The mechanisms of agitation in AD are poorly understood and the current interventions are only modestly effective while having serious adverse effects. In this study, the investigators propose to assess the mechanisms and treatment of neuropsychiatric symptoms in AD with the use of non-invasive, brain stimulation approaches. By applying magnetic stimulation to the surface of the head (transcranial magnetic stimulation - TMS) combined with electroencephalography (EEG), the investigators will be able to study the mechanisms of agitation and advance our understanding of AD. Further, the investigators will evaluate if transcranial direct current stimulation (tDCS) is effective to treat agitation dementia.
Recruiting0 awards N/A6 criteria
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Neurostimulation

for Mild Cognitive Impairment

More than 5 million people live with Alzheimer's dementia (AD) in North America. No effective treatment exists yet probably because by the time AD has developed it is too late to intervene. Mild Cognitive Impairment (MCI) is a clinical state that typically precedes AD. In MCI, the prefrontal cortex supports compensatory mechanisms that depend on robust synaptic plasticity and that delay progression to AD. Using a neurostimulation approach that enhances prefrontal cortical plasticity in vivo, this project aims to enhance prefrontal cortical plasticity and function in patients with MCI. If successful, this project would discover a treatment modality that enhances compensation in MCI and ultimately, prevents progression to AD.
Recruiting0 awards N/A13 criteria

More about Sanjeev Kumar, MD

Clinical Trial Related6 years of experience running clinical trials · Led 4 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Sanjeev Kumar, MD has experience with
  • TDCS
  • Paired Associative Stimulation (PAS)
  • Non-Pharmacological Intervention
  • Pharmacological Intervention

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