Dr. Philip Gerretsen, MD, PhD
Claim this profileCentre for Addiction and Mental Health
Studies Schizophrenia
Studies Mild Cognitive Impairment
7 reported clinical trials
10 drugs studied
Affiliated Hospitals
Clinical Trials Philip Gerretsen, MD, PhD is currently running
Psilocybin
for Mild Cognitive Impairment
The goal of this clinical trial is to investigate the effects of psilocybin on synaptic vesicular density (SVD) as measured by the positron emission tomography (PET) radiotracer, 18F-SynVesT-1, in participants with amnestic Mild Cognitive Impairment (aMCI) and healthy participants. The investigators hypothesize that SVD levels in the brain will be higher following the ingestion of psilocybin in comparison to placebo, and that increases in SVD will be associated with improvements in cognition. 60 participants (30 with aMCI, and 30 sex and age matched healthy volunteers) will: * Be randomized to receive either: 1. Two 25 mg macrodoses of psilocybin separated by 1 week. 2. Two placebo doses separated by 1 week. * Receive a baseline 18F-SynVesT-1 PET scan, clinical, and neuropsychological assessments. * Receive a 18F-SynVesT-1 PET scan one week after the last dose of treatment. * Receive a third PET scan at any time within 4 weeks of the screening visit to quantify tauopathy with the \[18F\]T807 radiotracer. * Receive clinical and neuropsychological testing 1, 4, and 12 weeks after the last treatment. Researchers will compare placebo vs. experimental groups to see if psilocybin will increase SVD, and if increases in SVD are associated with cognitive improvements.
Recruiting0 awards Phase 210 criteria
Brain Stimulation
for Schizophrenia
This study seeks to explore the effects of transcranial direct current stimulation (tDCS), a non-invasive method of brain stimulation, as an adjunctive treatment to improve antipsychotic medication adherence in patients with schizophrenia (SCZ). The investigators hypothesize that 20 sessions of tDCS will improve medication nonadherence in patients with SCZ.
Recruiting0 awards N/A5 criteria
More about Philip Gerretsen, MD, PhD
Clinical Trial Related1 year of experience running clinical trials · Led 7 trials as a Principal Investigator · 6 Active Clinical TrialsTreatments Philip Gerretsen, MD, PhD has experience with
- Placebo
- Psilocybin
- Investigational Brainstem Neuromodulation Device
- TDCS
- Active TDCS
- Sham TDCS
Breakdown of trials Philip Gerretsen, MD, PhD has run
Schizophrenia
Mild Cognitive Impairment
Lack of insight
Psychosis
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Philip Gerretsen, MD, PhD specialize in?
Philip Gerretsen, MD, PhD focuses on Schizophrenia and Mild Cognitive Impairment. In particular, much of their work with Schizophrenia has involved treating patients, or patients who are undergoing treatment.
Is Philip Gerretsen, MD, PhD currently recruiting for clinical trials?
Yes, Philip Gerretsen, MD, PhD is currently recruiting for 4 clinical trials in Toronto Ontario. If you're interested in participating, you should apply.
Are there any treatments that Philip Gerretsen, MD, PhD has studied deeply?
Yes, Philip Gerretsen, MD, PhD has studied treatments such as Placebo, Psilocybin, Investigational brainstem neuromodulation device.
What is the best way to schedule an appointment with Philip Gerretsen, MD, PhD?
Apply for one of the trials that Philip Gerretsen, MD, PhD is conducting.
What is the office address of Philip Gerretsen, MD, PhD?
The office of Philip Gerretsen, MD, PhD is located at: Centre for Addiction and Mental Health, Toronto, Ontario M5T 1R8 Canada. This is the address for their practice at the Centre for Addiction and Mental Health.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.