Dr. Shana McCormack

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Childrens Hospital of Philadelphia

Studies Obesity
Studies Brain Tumor
4 reported clinical trials
6 drugs studied

Affiliated Hospitals

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Children's Hospital Of Philadelphia
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Children's Hospital Of Philadephia

Clinical Trials Shana McCormack is currently running

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Phentermine/Topiramate

for Hypothalamic Obesity

Hypothalamic obesity (HO) refers to the substantial weight gain that often complicates hypothalamic brain tumors. Children with this treatment-recalcitrant form of obesity have excess rates of metabolic sequelae compared to otherwise healthy children with similar obesity, and later experience excess mortality related to cardiometabolic disease. In this pilot trial, our objective is to gather key preliminary data about phentermine/topiramate (Ph/T) that is FDA-approved for "common" obesity but has never been tested in HO. The subset of individuals with HO who experience hyperphagia or excess daytime sleepiness may benefit from the Ph/T-induced decrease in appetite and increase in alertness. Preliminary assessments of safety, adverse events, dosing (Aim 1), as well as of efficacy (% BMI loss, Aim 2) will be made in a 28-week parallel-arm double-blinded Phase 2 placebo-controlled clinical trial in 12-28-year-old individuals with HO.
Recruiting0 awards Phase 2

More about Shana McCormack

Clinical Trial Related6 years of experience running clinical trials · Led 4 trials as a Principal Investigator · 1 Active Clinical Trial
Treatments Shana McCormack has experience with
  • Phentermine/Topiramate
  • Flow-mediated Dilation Testing
  • Mixed Meal Tolerance Testing
  • Skin Conductance & Cold Pressor Test
  • Metreleptin
  • Setmelanotide
Breakdown of trials Shana McCormack has run
Obesity
Brain Tumor
Bone Cancer
Craniopharyngioma
Migraine

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Frequently asked questions

Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Shana McCormack specialize in?
Shana McCormack focuses on Obesity and Brain Tumor. In particular, much of their work with Obesity has involved treating patients, or patients who are undergoing treatment.
Is Shana McCormack currently recruiting for clinical trials?
Yes, Shana McCormack is currently recruiting for 1 clinical trial in Philadelphia Pennsylvania. If you're interested in participating, you should apply.
Are there any treatments that Shana McCormack has studied deeply?
Yes, Shana McCormack has studied treatments such as Phentermine/Topiramate, Flow-mediated dilation testing, Mixed meal tolerance testing.
What is the best way to schedule an appointment with Shana McCormack?
Apply for one of the trials that Shana McCormack is conducting.
What is the office address of Shana McCormack?
The office of Shana McCormack is located at: Childrens Hospital of Philadelphia, Philadelphia, Pennsylvania 19104 United States. This is the address for their practice at the Childrens Hospital of Philadelphia.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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