Dr. Sharad Khurana

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University of Arizona Cancer Center

Studies Acute Myelogenous Leukemia
Studies Acute Myeloid Leukemia
4 reported clinical trials
14 drugs studied

Area of expertise

1Acute Myelogenous Leukemia
Sharad Khurana has run 3 trials for Acute Myelogenous Leukemia. Some of their research focus areas include:
t(9;22) translocation positive
FLT3 positive
2Acute Myeloid Leukemia
Sharad Khurana has run 3 trials for Acute Myeloid Leukemia. Some of their research focus areas include:
t(9;22) translocation positive
FLT3 positive

Affiliated Hospitals

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Banner University Medical Center - Tucson
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University Of Arizona Cancer Center-North Campus

Clinical Trials Sharad Khurana is currently running

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Novel Therapies

for Acute Myeloid Leukemia

This phase II MyeloMATCH treatment trial tests whether the standard approach of cytarabine and daunorubicin in comparison to the following experimental regimens works to shrink cancer in patients with high risk acute myeloid leukemia (AML): 1) daunorubicin and cytarabine liposome alone; 2) cytarabine and daunorubicin with venetoclax; 3) azacitidine and venetoclax; 4) daunorubicin and cytarabine liposome and venetoclax. "High-risk" refers to traits that have been known to make the AML harder to treat. Cytarabine is in a class of medications called antimetabolites. It works by slowing or stopping the growth of cancer cells in the body. Daunorubicin is in a class of medications called anthracyclines. It also works by slowing or stopping the growth of cancer cells in the body. Azacitidine is in a class of medications called demethylation agents. It works by helping the bone marrow to produce normal blood cells and by killing abnormal cells. Venetoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. There is evidence that these newer experimental treatment regimens may work better in getting rid of more AML compared to the standard approach of cytarabine and daunorubicin.
Recruiting1 award Phase 217 criteria
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Screening Tool

for Myeloid Cancer

This MyeloMATCH Master Screening and Reassessment Protocol (MSRP) evaluates the use of a screening tool and specific laboratory tests to help improve participants' ability to register to clinical trials throughout the course of their myeloid cancer (acute myeloid leukemia or myelodysplastic syndrome) treatment. This study involves testing patients' bone marrow and blood for certain biomarkers. A biomarker (sometimes called a marker) is any molecule in the body that can be measured. Doctors look at markers to learn what is happening in the body. Knowing about certain markers can give doctors more information about what is driving the cancer and how to treat it. Testing patients' bone marrow and blood will show doctors if patients have markers that specific drugs can target. The marker testing in this study will let doctors know if they can match patients with a treatment study (myeloMATCH clinical trial) that tests treatment for the type of cancer they have or continue standard of care treatment with their doctor on the Tier Advancement Pathway (TAP).
Recruiting0 awards Phase 21 criteria

More about Sharad Khurana

Clinical Trial Related1 year of experience running clinical trials · Led 4 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Sharad Khurana has experience with
  • Azacitidine
  • Venetoclax
  • Cytarabine
  • Daunorubicin Hydrochloride
  • TAS1440
  • ATRA

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