Dr. Timothy S Olson, MD, PhD
Claim this profileChildren's Hospital of Philadelphia
Studies Aplastic Anemia
Studies Bone Marrow Failure Syndrome
16 reported clinical trials
31 drugs studied
Area of expertise
1Aplastic Anemia
SBDS positive
HLA positive
HLA-A positive
2Bone Marrow Failure Syndrome
HLA negative
CD3 positive
CD3 negative
Affiliated Hospitals
Clinical Trials Timothy S Olson, MD, PhD is currently running
IST + BMT
for Aplastic Anemia
Severe Aplastic Anemia (SAA) is a rare condition in which the body stops producing enough new blood cells. SAA can be cured with immune suppressive therapy or a bone marrow transplant. Regular treatment for patients with aplastic anemia who have a matched sibling (brother or sister), or family donor is a bone marrow transplant. Patients without a matched family donor normally are treated with immune suppressive therapy (IST). Match unrelated donor (URD) bone marrow transplant (BMT) is used as a secondary treatment in patients who did not get better with IST, had their disease come back, or a new worse disease replaced it (like leukemia). This trial will compare time from randomization to failure of treatment or death from any cause of IST versus URD BMT when used as initial therapy to treat SAA. The trial will also assess whether health-related quality of life and early markers of fertility differ between those randomized to URD BMT or IST, as well as assess the presence of marrow failure-related genes and presence of gene mutations associated with MDS or leukemia and the change in gene signatures after treatment in both study arms. This study treatment does not include any investigational drugs. The medicines and procedures in this study are standard for treatment of SAA.
Recruiting2 awards Phase 3
Treosulfan-Based Conditioning
for Bone Marrow Failure
This trial tests if a combination of three drugs can reduce complications for patients with bone marrow failure diseases. The drugs work by killing harmful cells, stopping their growth, and reducing immune reactions.
Recruiting1 award Phase 211 criteria
More about Timothy S Olson, MD, PhD
Clinical Trial Related7 years of experience running clinical trials · Led 16 trials as a Principal Investigator · 8 Active Clinical TrialsTreatments Timothy S Olson, MD, PhD has experience with
- Fludarabine
- Cyclophosphamide
- Horse Anti-Thymocyte Globulin (ATG)
- Low-dose Total Body Irradiation (TBI)
- Methotrexate
- Rabbit Anti-Thymocyte Globulin (ATG)
Breakdown of trials Timothy S Olson, MD, PhD has run
Aplastic Anemia
Bone Marrow Failure Syndrome
Pancytopenia Splenomegaly
Anemia
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Timothy S Olson, MD, PhD specialize in?
Timothy S Olson, MD, PhD focuses on Aplastic Anemia and Bone Marrow Failure Syndrome. In particular, much of their work with Aplastic Anemia has involved SBDS positive patients, or patients who are HLA positive.
Is Timothy S Olson, MD, PhD currently recruiting for clinical trials?
Yes, Timothy S Olson, MD, PhD is currently recruiting for 8 clinical trials in Philadelphia Pennsylvania. If you're interested in participating, you should apply.
Are there any treatments that Timothy S Olson, MD, PhD has studied deeply?
Yes, Timothy S Olson, MD, PhD has studied treatments such as Fludarabine, Cyclophosphamide, Horse Anti-Thymocyte Globulin (ATG).
What is the best way to schedule an appointment with Timothy S Olson, MD, PhD?
Apply for one of the trials that Timothy S Olson, MD, PhD is conducting.
What is the office address of Timothy S Olson, MD, PhD?
The office of Timothy S Olson, MD, PhD is located at: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104 United States. This is the address for their practice at the Children's Hospital of Philadelphia.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.