Yair Lotan, M.D.: Urology ...

Dr. Yair Lotan, MD

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University of Texas Southwestern Medical Center

Studies Bladder Cancer
Studies Transitional Cell Carcinoma
12 reported clinical trials
19 drugs studied

Area of expertise

1

Bladder Cancer

Yair Lotan, MD has run 9 trials for Bladder Cancer. Some of their research focus areas include:

Stage II
Stage I
2

Transitional Cell Carcinoma

Yair Lotan, MD has run 3 trials for Transitional Cell Carcinoma.

Affiliated Hospitals

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University Of Texas Southwestern Medical Center

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UT Southwestern Medical Center

Clinical Trials Yair Lotan, MD is currently running

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Gemcitabine vs Water Irrigation

for Urothelial Cancer

There is a high rate of intravesical (bladder) recurrence following extirpative surgery for upper tract urothelial carcinoma. There is no single established standard of care for prevention of intravesical recurrence; however, one protocol in common use involves the use of intravesical gemcitabine instilled into the bladder during surgery and prior to entry into the bladder. There are barriers to the use of gemcitabine, especially at lower volume centers. Some evidence suggests that intravesical irrigation with sterile water has equivalent efficacy to intravesical chemotherapy in prevention of recurrent bladder cancer following transurethral resection of bladder tumors (TURBT). This study is intended to compare recurrence rates using intravesical gemcitabine (as a pseudo-standard of care) and continuous bladder irrigation with sterile water.

Recruiting

2 awards

Phase 3

5 criteria

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Optimized Care

for Bladder Cancer

The proposed study is aimed at a comprehensive optimization at-time of radical cystectomy (COARC) intervention that focuses on patient optimization throughout the perioperative continuum, from the pre-operative setting to the post-operative period, among patients undergoing radical cystectomy for bladder cancer. This multi-modal strategy will focus on three phases of care around surgery: the pre-operative, peri-operative, and post-operative phases. The intervention group will focus on multiple areas of patient optimization including remote patient monitoring for the earlier identification of potential complications. The overall study mission is to decrease complication rates after radical cystectomy using this comprehensive approach.

Recruiting

1 award

N/A

1 criteria

More about Yair Lotan, MD

Clinical Trial Related

4 years of experience running clinical trials · Led 12 trials as a Principal Investigator · 9 Active Clinical Trials

Treatments Yair Lotan, MD has experience with

  • Curcumin
  • Cystoscopy With RedPine Flexible Disposable Cystoscope
  • Urinalysis
  • Preop Intervention And Monitored Recovery
  • Usual Care
  • Placebo

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