Nuprin

Insomnia, Catarrh, Chronic Pain + 33 more
Treatment
13 FDA approvals
20 Active Studies for Nuprin

What is Nuprin

IbuprofenThe Generic name of this drug
Treatment SummaryIbuprofen is a commonly used medication to reduce inflammation and pain. It was created in 1960 as an alternative to aspirin and was finally patented in 1961. Ibuprofen was first available for medical purposes in the UK in 1969 and the US in 1974. It can be purchased over-the-counter without a prescription. Ibuprofen is made of two components, the R-enantiomer and the S-enantiomer. The S-enantiomer is believed to have a stronger effect on reducing inflammation and pain.
Motrinis the brand name
image of different drug pills on a surface
Nuprin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Motrin
Ibuprofen
1974
2460

Approved as Treatment by the FDA

Ibuprofen, also called Motrin, is approved by the FDA for 13 uses including Acute Pain and Dysmenorrhea .
Acute Pain
Used to treat Pain, Acute in combination with Oxycodone
Dysmenorrhea
Gastric Ulcer
Used to treat Gastric Ulcer in combination with Famotidine
Stomach Ulcer
Used to treat Gastric Ulcer in combination with Famotidine
Pain, Acute
Used to treat Pain, Acute in combination with Oxycodone
Osteoarthritis (OA)
Used to treat Osteoarthritis (OA) in combination with Famotidine
Mild pain
Rheumatoid Arthritis
Used to treat Rheumatoid Arthritis in combination with Famotidine
Migraine
Osteoarthritis
Used to treat Osteoarthritis (OA) in combination with Famotidine
Fever
Headache
Menstrual Distress (Dysmenorrhea)

Effectiveness

How Nuprin Affects PatientsIbuprofen works to reduce pain, fever, and inflammation by blocking the enzymes (COX-1 and COX-2) that produce certain hormones (prostanoids). It can also reduce the pain transmission that occurs in the spinal cord and brain. Ibuprofen helps with dental procedures by decreasing inflammation and swelling in the affected area. It can also reduce joint pain for those with rheumatic diseases. Ibuprofen is widely used in over-the-counter products to reduce menstrual pain, fever, and migraines. Low doses of ibuprofen over a long period of time may reduce neurodeg
How Nuprin works in the bodyIbuprofen is a type of medicine called a non-steroidal anti-inflammatory drug (NSAID). It works by blocking two enzymes called cyclooxygenase-1 and cyclooxygenase-2. By blocking these enzymes, ibuprofen reduces pain, fever and inflammation, while also causing some side effects like stomach ulcers.

When to interrupt dosage

The measure of Nuprin relies upon the determined illness, for example, smooth muscle relaxation before radiological techniques, Catarrh and Pain alleviation. The quantity of dosage is contingent upon the mode of delivery (e.g. Kit - Oral; Topical or Tablet) featured in the following table.
Condition
Dosage
Administration
Chronic Pain
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Migraine
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Analgesics
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Pain relief
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Pain
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Fever
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Fistula
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Migraine Disorders
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Muscle Spasticity
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Opioids
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Stomach Ulcer
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Nasal Congestion
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Arthritis, Gouty
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Spasm
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Dysmenorrhea
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Premature Birth
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Juvenile arthritis
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Muscle Relaxation
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Osteoarthritis
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical
Pain
200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL
Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, chewable - Oral, Tablet, chewable, Tablet, Tablet - Oral, Suspension / drops - Oral, Liquid, Liquid - Oral, Suspension, Kit, Suspension / drops, Kit - Oral, Solution, Solution - Oral, Capsule, Capsule - Oral, Capsule, coated, Capsule, coated - Oral, Intravenous, Solution - Intravenous, Kit; Tablet, Capsule; Kit, Kit; Tablet - Oral, Capsule; Kit - Oral, Injection, solution, Injection - Intravenous, Tablet, extended release, Injection, solution - Intravenous, Injection, Tablet, extended release - Oral, Kit - Oral; Topical, Cream - Topical, Oral; Topical, Topical, Kit - Topical, Solution - Topical, Gel - Topical, Gel, Solution / drops - Oral, Ophthalmic; Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream, Solution / drops, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical

Warnings

Nuprin has two contraindications and should not be utilized when suffering from the issues listed in the following table.Nuprin Contraindications
Condition
Risk Level
Notes
Coronary Artery Bypass Grafting
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Nuprin.
Common Nuprin Drug Interactions
Drug Name
Risk Level
Description
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Ibuprofen.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Ibuprofen.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Ibuprofen.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Ibuprofen.
Fluorouracil
Major
The metabolism of Fluorouracil can be decreased when combined with Ibuprofen.
Nuprin Toxicity & Overdose RiskTaking more than 99 mg/kg of ibuprofen can cause abdominal pain, nausea, vomiting, fatigue, dizziness, vertigo, insomnia, headaches, fainting, ringing in the ears, depression of the central nervous system, seizures, and difficulty breathing. Very young pediatric patients may experience metabolic acidosis, abnormal liver function, high potassium levels, kidney failure, coma, and apnea. The toxic dose of ibuprofen for rats is 636 mg/kg, for mice is 740 mg/kg, and for guinea pigs is 495 mg/kg.

Nuprin Novel Uses: Which Conditions Have a Clinical Trial Featuring Nuprin?

531 active studies are assessing the potential of Nuprin to reduce symptoms of Rheumatoid Arthritis, Chronic Pain and Migraines.
Condition
Clinical Trials
Trial Phases
Premature Birth
25 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1
Influenza
0 Actively Recruiting
Pain
0 Actively Recruiting
Aquaporin 2
3 Actively Recruiting
Phase 3, Not Applicable, Phase 2
Chronic Pain
130 Actively Recruiting
Not Applicable, Phase 4, Phase 2, Phase 3, Early Phase 1, Phase 1
Migraine
51 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 3, Phase 2, Early Phase 1
Rheumatoid Arthritis
55 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Muscle Relaxation
0 Actively Recruiting
Juvenile arthritis
8 Actively Recruiting
Phase 2, Not Applicable, Phase 3
Migraine
13 Actively Recruiting
Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4
Acute Pain
1 Actively Recruiting
Not Applicable
Primary Dysmenorrhoea
1 Actively Recruiting
Not Applicable
Nasal Congestion
0 Actively Recruiting
Catarrh
0 Actively Recruiting
Pericarditis
1 Actively Recruiting
Phase 2, Phase 3
Arthritis, Gouty
0 Actively Recruiting
Insomnia
0 Actively Recruiting
Pain
0 Actively Recruiting
Cystic Fibrosis
0 Actively Recruiting
Pain
0 Actively Recruiting

Nuprin Reviews: What are patients saying about Nuprin?

5Patient Review
3/16/2009
Nuprin for Pain
3.7Patient Review
2/6/2020
Nuprin for Migraine Headache
IT TOOK THE HEADACHE AWAY BUT IT MADE MY WHOOOLE BODY ITCH

Patient Q&A Section about nuprin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What drug is Nuprin?

"Nuprin Ibuprofen is an NSAID that is used to treat mild to moderate pain, and helps to relieve symptoms of arthritis such as inflammation, swelling, stiffness, and joint pain."

Answered by AI

Why was Nuprin taken off the market?

"New jersey's pharmacists believe that ibuprofen, while safe and effective as a prescription drug, may be dangerous for those with heart or kidney trouble, hypertension, or other medical conditions when used without a prescription in Advil and Nuprin. This is especially true for pregnant women."

Answered by AI

What are Nuprin tablets used for?

"Nuprin is taken to reduce the risk of blood clots forming and thereby prevent further: • heart attacks • strokes • cardiovascular problems in patients who suffer from stable angina (a type of chest pain)."

Answered by AI

Is there aspirin in Nuprin?

"Aspirin that is taken once a day at a low dose is a medication that prevents blood clotting. It is also called acetylsalicylic acid. You need a prescription to be able to get it, and it is also sold under the brand names Caprin, Nuprin, and Nu-seals."

Answered by AI

Clinical Trials for Nuprin

Image of California Clinical Trials Medical Group in Glendale, United States.

NTR-1011 for Lupus and Rheumatoid Arthritis

18 - 75
All Sexes
Glendale, CA
This phase 1a and 1b study is designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary efficacy of NTR-1011 in healthy adults and in adult patients with systemic lupus erythematosus and rheumatoid arthritis. The main goals of this study are to determine the safety profile of NTR-1011 across subcutaneous and intravenous dose levels, understand how the drug behaves in the body, characterize its biological activity through relevant pharmacodynamic markers, assess the potential for immune responses to treatment, and explore early signals of clinical benefit in autoimmune disease settings. This is a randomized, double blind, placebo controlled study that begins with a single ascending dose evaluation in healthy volunteers followed by a multiple dose assessment in patients. The design is intended to define the highest safe and well tolerated dose, establish a robust PK and PD baseline, and generate initial patient level evidence to support dose selection and advancement into subsequent clinical development.
Phase 1
Recruiting
California Clinical Trials Medical GroupHakop Gevorkyan, MDNeutrolis
Have you considered Nuprin clinical trials? We made a collection of clinical trials featuring Nuprin, we think they might fit your search criteria.Go to Trials
Image of Johns Hopkins Medicine in Baltimore, United States.

Embolization for Migraine

18 - 80
All Sexes
Baltimore, MD
This study is to test the safety and feasibility of a procedure called embolization of the middle meningeal arteries (MMA), using a product called Onyx. Embolization creates a plug in the arteries. MMA embolization with Onyx is not approved for use in patients with migraines, but is currently used in patients with subdural hematomas. The FDA is allowing the use of Onyx in this study. It is thought that by using Onyx to block the middle meningeal arteries, the amount of migraine-causing substances which are released into the brain's bloodstream will be reduced. The company that manufactures Onyx, Medtronic, is providing the supplies for this study. Participants will be in the study for about 8 months after enrolling, including 6 months of follow up after the procedure. The participants will be asked to complete a daily headache diary and continue the participant's regular migraine medications. Participants will also have several clinic visits and be asked to provide blood samples for research.
Waitlist Available
Has No Placebo
Johns Hopkins MedicineRisheng Xu, MD, PhDMedtronic
Image of Baylor College of Medicine/Texas Children's Hospital in Austin, United States.

Guided Imagery Therapy for Abdominal Pain

7 - 12
All Sexes
Austin, TX
Chronic abdominal pain is common among children, and the majority of cases are attributed to functional abdominal pain disorders. One approach to treating these disorders is by using psychological therapies. This clinical trial aims to see how well pre-recorded guided imagery therapy sessions help children's abdominal pain when delivered via a mobile application (app) on a smartphone or tablet. Participants will complete a baseline abdominal pain and stooling diary to determine eligibility, as well as other surveys. Eligible participants will be given access to the guided imagery therapy mobile application. This intervention asks participants to listen to a 10- to 15-minute GIT session 5 out of 7 days per week for 8 weeks, in addition to their usual care for their abdominal pain. Then, participants will complete another abdominal pain and stooling diary, along with other psychometric surveys, at the end of this intervention period. Participants will also collect another diary and surveys 3 months post-treatment.
Waitlist Available
Has No Placebo
Baylor College of Medicine/Texas Children's Hospital (+1 Sites)
Image of Weill Cornell Medical College in New York, United States.

Health Coaching for Rheumatoid Arthritis

18+
All Sexes
New York, NY
The goal of this clinical trial is to learn if peer coaching works to reduce levels of anxiety and/or depression in adults diagnosed with Rheumatoid Arthritis (RA). The main questions it aims to answer are: Do people with RA who complete the intervention with a peer coach have lower levels of anxiety and/or depression at 6 months from baseline? Do people with RA who complete the intervention with a peer coach have lower levels of anxiety and/or depression at 6 months compared to those in the control arm? Researchers will compare the peer coaching intervention to an active-control arm (where people without RA coach participants on general health and nutrition topics) to see if peer coaching works to reduce anxiety and/or depression. Participants will meet with a coach every week for 9 weeks and complete several surveys before, during and after the intervention
Recruiting
Has No Placebo
Weill Cornell Medical CollegeIris Y Navarro-Millán, MDBristol-Myers Squibb
Image of Humana Healthcare Research, Inc. in Louisville, United States.

Academic Detailing for Rheumatoid Arthritis

Any Age
All Sexes
Louisville, KY
The goal of this trial is to learn if an interactive evidence-based educational outreach visits to clinicians who prescribe biologics change prescribing of biosimilar medications. The main questions it aims to answer are: 1. Do educational outreach visits lead to a higher number of prescriptions for biosimilar versions of adalimumab? 2. Do in-person or virtual visits work better? Researchers will compare clinicians offered the educational outreach visit to those who are not offered the visit to see if there is a difference in prescribing of biosimilar versions of adalimumab instead of the original brand-name version. Participants will be offered the chance to meet with a trained clinician who will provide educational information tailored to their knowledge and attitudes on the topic. They will also be provided an educational brochure and patient educational materials.
Waitlist Available
Has No Placebo
Humana Healthcare Research, Inc. (+1 Sites)
Have you considered Nuprin clinical trials? We made a collection of clinical trials featuring Nuprin, we think they might fit your search criteria.Go to Trials
Image of Washington University School of Medicine in St Louis, United States.

Pain Mechanisms for Juvenile Arthritis

9 - 17
All Sexes
St Louis, MO
Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disease in children. The main symptoms of JIA, which are often the primary focus of treatment, include joint swelling, stiffness, and tenderness. Additional symptoms can include malaise, fatigue, and pain. However, the exact mechanisms contributing to pain are not yet fully understood. Participants will complete a 2.5-hours study session. In the study session, psychophysical assessments of thermal and pressure stimuli will be performed. In addition, demographic, social, pubertal maturation, and behavioral and psychological factors will be collected via questionnaires. A saliva sample and/or blood draw may occur for the analysis of various immune factors and sex hormones. If a joint aspiration is done as part of their standard of care, we will request a sample of the synovial fluid for analyses of immune, hormonal and/or genetic factors. Participants will have the option to participate in additional optional follow-up study visits (every 3 months, up to 1 year) and to complete monthly surveys asking about their juvenile arthritis.
Recruiting
Has No Placebo
Washington University School of MedicineHadas Nahman-Averbuch, PhD
Have you considered Nuprin clinical trials? We made a collection of clinical trials featuring Nuprin, we think they might fit your search criteria.Go to Trials
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