Your session is about to expire
← Back to Search
Device
Brain Stimulation for Epilepsy
Phase < 1
Waitlist Available
Research Sponsored by Stanford University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up within 1 week of end of the short treatment and within 1 week of end of the long treatment
Awards & highlights
No Placebo-Only Group
Summary
This trial will test whether a brain stimulation technique called tDCS can help reduce seizures and EEG spikes. tDCS will be done at home, and participants will be randomly assigned to either receive real tDCS or a fake (placebo) version.
Who is the study for?
This trial is for adults aged 18-100 with epilepsy, experiencing at least four seizures per month and who haven't found seizure control with two or more anti-seizure medications. Participants must be able to keep their medication constant, understand consent in English, and maintain a seizure diary. It's not suitable for those with certain psychiatric conditions, skin issues affecting electrode placement, or women who are pregnant.
What is being tested?
The study tests if using transcranial direct current stimulation (tDCS) at home can reduce the number of seizures and EEG spikes in people with epilepsy. This placebo-controlled study means some participants will receive the tDCS treatment while others will get a sham procedure without any active intervention.
What are the potential side effects?
Potential side effects of tDCS may include discomfort at the electrode sites on the scalp, itching, tingling sensations during application, headache after treatment sessions, fatigue or nausea. Serious side effects are rare but could involve changes in mood or cognitive function.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ recorded at time of study entry (baseline) and within 1 week of end of the long treatment
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~recorded at time of study entry (baseline) and within 1 week of end of the long treatment
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Change in seizures per month
Secondary study objectives
Change in duration of seizures
Change in severity of seizures
Number of epileptiform EEG spikes
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Long StimulationExperimental Treatment1 Intervention
30 minutes duration of stimulation per day for 30 days
Group II: Short StimulationActive Control1 Intervention
1 minute duration of stimulation per day for 30 days
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
transcranial direct current stimulation (tDCS)
2014
N/A
~820
Find a Location
Who is running the clinical trial?
Stanford UniversityLead Sponsor
2,484 Previous Clinical Trials
17,516,091 Total Patients Enrolled
16 Trials studying Epilepsy
1,193 Patients Enrolled for Epilepsy