Pantoprazole for Nausea and Vomiting
Trial Summary
The trial protocol does not specify if you need to stop taking your current medications. However, if you are using H2 receptor blockers, proton pump inhibitors, or other GERD-specific therapies, you cannot participate in the trial.
The available research shows that Pantoprazole is effective in treating conditions related to stomach acid, like reflux oesophagitis and gastric ulcers, by reducing acid production. However, there is no specific data provided about its effectiveness for nausea and vomiting. Pantoprazole is compared to other drugs like ranitidine and omeprazole for acid-related conditions, but not directly for nausea and vomiting. Therefore, while it is effective for acid-related issues, there is no direct evidence here supporting its use for nausea and vomiting.
12345Pantoprazole is a proton pump inhibitor used to treat acid-related diseases. It has been approved in over 100 countries and used for over 13 years, with an excellent safety profile and low potential for drug-drug interactions. Rare cases of hepatotoxicity have been reported, but it is generally well-tolerated. Common side effects of similar drugs include headache, dizziness, skin rash, and gastrointestinal issues. Pantoprazole is available in oral and intravenous forms and is effective across all age groups, though primarily indicated for adults.
46789The research articles focus on other drugs like serotonin receptor antagonists and neurokinin-1 receptor antagonists for treating nausea and vomiting, especially in cancer patients. Pantoprazole is not mentioned as a promising treatment for these symptoms in the provided studies.
1011121314Eligibility Criteria
This trial is for women aged 18-79 undergoing gynecologic surgery, aiming to see if pantoprazole can prevent postoperative nausea and vomiting. Specific eligibility criteria are not provided.Inclusion Criteria
Exclusion Criteria
Participant Groups
Pantoprazole is already approved in United States, European Union, Canada, Japan, China, Switzerland for the following indications:
- Erosive esophagitis
- Gastroesophageal reflux disease (GERD)
- Zollinger-Ellison syndrome
- Erosive esophagitis
- Gastroesophageal reflux disease (GERD)
- Zollinger-Ellison syndrome
- Peptic ulcer disease
- Erosive esophagitis
- Gastroesophageal reflux disease (GERD)
- Zollinger-Ellison syndrome
- Erosive esophagitis
- Gastroesophageal reflux disease (GERD)
- Zollinger-Ellison syndrome
- Erosive esophagitis
- Gastroesophageal reflux disease (GERD)
- Zollinger-Ellison syndrome
- Erosive esophagitis
- Gastroesophageal reflux disease (GERD)
- Zollinger-Ellison syndrome