Quit2Heal App for Smoking Cessation in Cancer Patients

Recruiting in Palo Alto (17 mi)

+1 other location

Overseen by Jonathan B Bricker

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 3

Waitlist Available

Sponsor: Fred Hutchinson Cancer Research Center

No Placebo Group

Pivotal Trial (Near Approval)

Prior Safety Data

Trial Summary

What is the purpose of this trial?

This phase III trial compares the Quit2Heal smoking cessation smartphone application (app) to the QuitGuide app in helping cancer patients quit smoking. Both apps provide tools to cope with urges to smoke, step-by-step guides for quitting smoking, help in planning for quitting and staying tobacco-free, and scientifically-based recommendations for how to select medications that aid in smoking cessation.

Research Team

Jonathan B Bricker

Principal Investigator

Fred Hutch/University of Washington Cancer Consortium

Eligibility Criteria

This trial is for adults over 18 in the US who have been diagnosed with cancer within the last two years or are undergoing treatment. Participants must be current smokers interested in quitting, willing to use a smartphone app for cessation, and able to complete surveys. They should not be using other quit-smoking programs or have used NCI's QuitGuide app.

Inclusion Criteria

Providing email, phone number(s), and mailing address

I am 18 years old or older.

Not currently (i.e., within past 30 days) using other smoking cessation interventions

Exclusion Criteria

Has used the NCI's QuitGuide app

Not providing email, phone number(s), and mailing address

I have used other methods to quit smoking in the last 30 days.

Treatment Details

Interventions

• Quit2Heal Smartphone App (Behavioural Intervention)
• QuitGuide App (Behavioural Intervention)

Trial Overview The study compares two smoking cessation apps: Quit2Heal and QuitGuide. Both offer strategies to handle cravings, guides on quitting, staying smoke-free plans, and advice on choosing medications that help stop smoking. Patients will randomly receive one of these apps.

Participant Groups

Group I: Arm I (Quit2Heal app) Experimental Treatment 2 Interventions

Patients receive the Quit2Heal app and are encouraged to use it frequently. During the entire 12-month follow-up period, the app will remain fully available anytime study participants wish to use it.

Group II: Arm II (QuitGuide app) Active Control 2 Interventions

Patients receive the QuitGuide app and are encouraged to use it frequently. During the entire 12-month follow-up period, the app will remain fully available anytime study participants wish to use it.

Who Is Running the Clinical Trial?

Fred Hutchinson Cancer Research Center

Lead Sponsor

Trials

444

Recruited

148,000+

Dr. Nancy Davidson

Fred Hutchinson Cancer Research Center

Chief Medical Officer since 2020

MD from Harvard Medical School

Dr. Thomas J. Lynch Jr.

Fred Hutchinson Cancer Research Center

Chief Executive Officer since 2020

MD from Yale University, BA from Yale College

Fred Hutchinson Cancer Center

Lead Sponsor

Trials

583

Recruited

1,341,000+

Dr. W. Thomas Purcell

Fred Hutchinson Cancer Center

Chief Medical Officer since 2022

MD from Emory University School of Medicine, MBA from University of Chicago

Dr. Thomas J. Lynch Jr.

Fred Hutchinson Cancer Center

Chief Executive Officer since 2020

MD from Yale School of Medicine

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+

Dr. Douglas R. Lowy

National Cancer Institute (NCI)

Chief Executive Officer since 2023

MD from New York University School of Medicine

Dr. Monica Bertagnolli

National Cancer Institute (NCI)

Chief Medical Officer since 2022

MD from Harvard Medical School

Memorial Sloan Kettering Cancer Center

Collaborator

Trials

1,998

Recruited

602,000+

Lisa M. DeAngelis

Memorial Sloan Kettering Cancer Center

Chief Medical Officer since 2021

MD from Columbia University

Selwyn M. Vickers

Memorial Sloan Kettering Cancer Center

Chief Executive Officer since 2022

MD from Johns Hopkins University

American Cancer Society, Inc.

Collaborator

Trials

237

Recruited

110,000+

Dr. Larry Weiss

American Cancer Society, Inc.

Chief Medical Officer since 2016

MD from Duke University Medical Center

Dr. Wayne A. I. Frederick

American Cancer Society, Inc.

Chief Executive Officer

MD from Howard University, MBA from Howard University