Smoking Cessation Intervention for Cancer Patients

Recruiting in Palo Alto (17 mi)

Overseen by Jamie Ostroff, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Memorial Sloan Kettering Cancer Center

No Placebo Group

Trial Summary

What is the purpose of this trial?

The purpose of this study is to see if we can find ways to improve the treatment of tobacco dependence in patients who have cancer or may have cancer. We will compare two ways to help people quit tobacco use before surgery and to stay quit after surgery. One way is a scheduled reduced smoking program followed by use of the nicotine patch. In this program, the tobacco user will gradually cut down on their tobacco use until they quit. Once they quit, they will be offered the nicotine patch. We will compare this approach to our current program of counseling and use of nicotine patch. What we learn from this study may help us to develop new ways to help tobacco users and improve our current smoking cessation program.

Research Team

Jamie Ostroff, PhD

Principal Investigator

Memorial Sloan Kettering Cancer Center

Eligibility Criteria

This trial is for adults over 18 with cancer or a mass that might be cancer, who are not in the distant metastatic stage and are candidates for surgery in no less than 7 days. Participants must be mentally sound, able to use a phone and PDA, willing to consent, and smoke more than 8 cigarettes daily or frequently use other tobacco.

Inclusion Criteria

I am 18 years old or older.

I smoke more than 8 cigarettes a day and have smoked in the last week.

Have manual dexterity and sensory (i.e., visual and auditory) acuity sufficient to use a Personal Digital Assistant (PDA)

Treatment Details

Interventions

• Hospital Counseling + Nicotine Replacement + Presurgical Scheduled Reduced Smoking (Behavioral Intervention)
• Hospital Counseling + Nicotine Replacement Therapy (Behavioral Intervention)

Trial Overview The study compares two smoking cessation methods before surgery: one uses scheduled reduced smoking plus nicotine patches; the other employs hospital counseling alongside nicotine patches. The goal is to determine which method better helps patients quit tobacco use pre- and post-surgery.

Participant Groups

Group I: 2 Experimental Treatment 1 Intervention

Hospital Counseling + Nicotine Replacement Therapy + Pre-surgical Schedule Reduced Smoking (HC+NRT+PS/SRS)

Group II: 1 Active Control 1 Intervention

Hospital Counseling + Nicotine Replacement Therapy (HC+NRT)

Who Is Running the Clinical Trial?

Memorial Sloan Kettering Cancer Center

Lead Sponsor

Trials

1,998

Recruited

602,000+

Lisa M. DeAngelis

Memorial Sloan Kettering Cancer Center

Chief Medical Officer since 2021

MD from Columbia University

Selwyn M. Vickers

Memorial Sloan Kettering Cancer Center

Chief Executive Officer since 2022

MD from Johns Hopkins University

M.D. Anderson Cancer Center

Collaborator

Trials

3,107

Recruited

1,813,000+

Dr. Peter WT Pisters

M.D. Anderson Cancer Center

Chief Executive Officer since 2017

MD from University of Western Ontario

Dr. Jeffrey E. Lee

M.D. Anderson Cancer Center

Chief Medical Officer

MD from Stanford University School of Medicine