Noninvasive Brain Stimulation for Mild Cognitive Impairment

N/A

Recruiting

Led By David Ziegler, PhD

Research Sponsored by University of California, San Francisco

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

comfortably ambulatory healthy physical condition normal or corrected to normal visual auditory acuity fluency in spoken English Between 60-85 years old No neurological or psychiatric disorders No substance abuse Not taking anti-depressants Not taking anti-anxiety medication No history of seizures No color blindness No glaucoma No macular degeneration No amblyopia (lazy eye) No strabismus (cross eyed) Aneurysm clip(s) No Cardiac pacemaker No Implanted cardioverter defibrillator (ICD) No Electronic implant or device No Magnetically-activated implant or device No Neurostimulation system No Spinal cord stimulator No Internal electrodes or wires No Bone growth/bone fusion stimulator No Cochlear, otologic, or other ear implant No Insulin or other infusion pump No Implanted drug infusion device No type of prosthesis (eye, penile, etc.) No Heart valve prosthesis No Eyelid spring or wire No Artificial or prosthetic limb No Metallic stent, filter, or coil No Shunt (spinal or intraventricular) No Vascular access port and/or catheter No Radiation seeds or implants No Swan-Ganz or thermodilution catheter No Medication patch (Nicotine, Nitroglycerine) No metallic fragment or metallic foreign body in/on the body that can not be removed No Wire mesh implant No Tissue expander (e.g., breast) No Surgical staples, clips, or metallic sutures No Joint replacement (hip, knee, etc.) No Bone/joint pin, screw, nail, wire, plate, etc. No IUD, diaphragm, or pessary No Dentures or partial plates that can not be removed No Tattoo or permanent makeup No Body piercing jewelry No Claustrophobi

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline and immediate follow-up

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to see if a combination treatment involving brain stimulation and digital cognitive interventions can improve memory and overall well-being in adults with mild memory problems.

Who is the study for?

This trial is for adults with mild cognitive impairment (MCI), a condition where people have slight but noticeable and measurable decline in cognitive abilities, including memory and thinking skills. Specific eligibility criteria are not provided.

What is being tested?

The study tests if noninvasive brain stimulation (tACS) combined with digital cognitive exercises (MediTrain or Worder) can improve cognition and wellbeing in MCI patients. Participants will also use wrist-worn sensors to monitor various health metrics.

What are the potential side effects?

Potential side effects of tACS may include mild discomfort, itching, tingling at the electrode sites, headache or fatigue. Digital interventions typically do not have side effects; however, screen time might cause eye strain.