What is the mechanism of action of this treatment?

Common treatments for depression include cognitive-behavioral therapy (CBT), interpersonal psychotherapy (IPT), and mindfulness-based cognitive therapy (MBCT). CBT works by helping patients identify and change negative thought patterns and behaviors, IPT focuses on improving interpersonal relationships and social functioning, and MBCT combines mindfulness practices with cognitive therapy to prevent relapse. These therapies are similar to the M-O-M-S Pilot Intervention, which emphasizes cognitive and relationship changes and mental preparation. Understanding these mechanisms is crucial for depression patients as it empowers them to actively participate in their treatment, enhances adherence, and improves overall outcomes by addressing the root causes of their symptoms.

What side effects are associated with this type of intervention?

Common treatments for depression include cognitive-behavioral therapy (CBT) and pharmacotherapy with selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs). CBT generally has minimal side effects, though it may initially increase anxiety as patients confront distressing thoughts. SSRIs and SNRIs can cause side effects such as nausea, insomnia, sexual dysfunction, and weight gain. It's important to discuss these potential side effects with a healthcare provider to tailor the treatment to individual needs.

What prior FDA approvals exist?

The FDA has approved several medications for the treatment of depression, including selective serotonin reuptake inhibitors (SSRIs) like fluoxetine and sertraline, serotonin-norepinephrine reuptake inhibitors (SNRIs) such as venlafaxine and duloxetine, and atypical antidepressants like bupropion. In addition to pharmacotherapy, cognitive behavioral therapy (CBT) and interpersonal psychotherapy (IPT) are well-established psychotherapeutic approaches for depression. These treatments align with the M-O-M-S Pilot Intervention's focus on cognitive and relationship changes, providing a comprehensive approach to managing depression.

What other types of research exist?

Promising alternatives to the M-O-M-S Pilot Intervention for depression in pregnant women include: 1) Digital Cognitive Behavioral Therapy (CBT) programs, which offer flexibility and accessibility for pregnant women. 2) Integrative approaches combining mindfulness-based stress reduction (MBSR) with traditional therapy to address both mental and physical health. 3) Group therapy sessions specifically tailored for pregnant women, providing peer support and shared experiences. 4) Telehealth services offering remote therapy sessions, which can be particularly beneficial in disaster-affected or rural areas. These alternatives have shown potential in improving mental health outcomes and can be considered for treatment in 2024.

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M-O-M-S on the Bayou Program for Mental Health in Pregnancy

N/A

Recruiting

Research Sponsored by Tulane University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 weeks

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to help pregnant women in disaster-affected areas by providing classes led by experienced mothers. These classes offer emotional support to reduce anxiety and depression, promoting healthier pregnancies.

Who is the study for?

This trial is for pregnant women under 20 weeks' gestation, enrolled in prenatal care, and living in areas affected by a natural disaster. Participants must be over 18 and plan to carry to term and stay in the study area throughout pregnancy. They should speak English or Spanish.

What is being tested?

The 'M-O-M-S on the Bayou' intervention aims to improve mental health among pregnant women post-disaster. It includes classes on cognitive changes during pregnancy, relationship shifts, and preparing mentally for labor led by experienced mothers.

What are the potential side effects?

Since this is a non-medical intervention focusing on education and support through mentorship, there are no direct medical side effects expected from participating in this program.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Pregnancy-specific anxiety

Secondary study objectives

Depressive symptoms

Other study objectives

Acceptability

Fidelity

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: MOMS on the Bayou Intervention GroupExperimental Treatment1 Intervention

Participants complete intervention protocol.

Do I qualify?Apply below to find out

Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.

Mechanism Of Action

Side Effect Profile

Prior Approvals

Other Research

Common treatments for depression include cognitive-behavioral therapy (CBT), interpersonal psychotherapy (IPT), and mindfulness-based cognitive therapy (MBCT). CBT works by helping patients identify and change negative thought patterns and behaviors, IPT focuses on improving interpersonal relationships and social functioning, and MBCT combines mindfulness practices with cognitive therapy to prevent relapse. These therapies are similar to the M-O-M-S Pilot Intervention, which emphasizes cognitive and relationship changes and mental preparation. Understanding these mechanisms is crucial for depression patients as it empowers them to actively participate in their treatment, enhances adherence, and improves overall outcomes by addressing the root causes of their symptoms.

Brief psychotherapy: current status.Motivational Interviewing: An Evidence-Based Approach for Use in Medical Practice.Delineating mechanisms of change in child and adolescent therapy: methodological issues and research recommendations.