Resveratrol for Exercise Performance and Recovery
Trial Summary
What is the purpose of this trial?
To examine the effects of once daily supplementation with 500mg VeriSperse® resveratrol (VRES) for 17 days on muscle function, delayed onset muscle soreness, systemic concentrations of muscular damage markers and markers of oxidative stress in resistance trained young adult males following a damaging isoinertial squat protocol (ISP).
Will I have to stop taking my current medications?
The trial requires participants to stop taking any performance-enhancing drugs and nutritional supplements known to improve physical performance for at least 28 days before starting the study. Regular use of prescription or over-the-counter medications that affect performance is also not allowed.
What data supports the effectiveness of the drug Resveratrol for exercise performance and recovery?
Is resveratrol generally safe for humans?
Resveratrol, found in red wine and other foods, has been studied for its potential health benefits, including anti-inflammatory and antioxidant effects. While specific safety data for humans is limited, it is generally considered safe in moderate amounts, as it is naturally present in foods like grapes and peanuts.12367
How does the drug resveratrol differ from other treatments for exercise performance and recovery?
Resveratrol is unique because it is a natural compound found in red wine that may improve exercise endurance and muscle metabolism by activating sirtuins, which are proteins involved in cellular health. Unlike other treatments, it also has antioxidant and anti-inflammatory properties, potentially offering additional health benefits.128910
Research Team
Eligibility Criteria
This trial is for young adult males who regularly engage in resistance training. They must be healthy and willing to take a daily supplement or placebo for 17 days, then perform specific squat exercises.Inclusion Criteria
Exclusion Criteria
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive once daily supplementation with 500mg VeriSperse® resveratrol or placebo for 17 days
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Resveratrol (Other)
Resveratrol is already approved in Canada for the following indications:
- Dietary supplement for cardiovascular health and antioxidant properties
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Central Florida
Lead Sponsor
Dr. Michael Pape
University of Central Florida
Chief Executive Officer since 2015
PhD in Biochemistry from Purdue University, MBA from the University of Chicago Booth School of Business
Dr. James J. Hickman
University of Central Florida
Chief Medical Officer since 2020
MD from University of Central Florida College of Medicine
Gencor Pacific Group
Industry Sponsor