Using Near-infrared Spectroscopy (NIRS) Monitor to Noninvasively Evaluate Hepatic Venous Saturation

Recruiting in Palo Alto (17 mi)

Overseen by Rohit Rao, MD

Age: < 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Phoenix Children's Hospital

No Placebo Group

Trial Summary

What is the purpose of this trial?

Clinical studies are required to validate the hepatic NIRS monitor with other regional and global hemodynamic parameters and to evaluate its clinical use for continuous non-invasive hemodynamic monitoring. Using newer NIRS sensors the correlation between hepatic regional oxygen saturation and hepatic venous oxygen saturation (SvHO2) needs to be determined. If found to correlate then the NIRS can be used to evaluate early liver transplant failure and/or hepatic artery thrombosis, used as an early marker for shock, and necrotizing enterocolitis, and finally used in the outpatient setting to evaluate patients with chronic liver pathologies. If our validation study finds that NIRS monitors are an appropriate marker of hepatic venous saturation then it will lead to further clinical studies.

Research Team

Rohit Rao, MD

Principal Investigator

Phoenix Children's Hospital

Eligibility Criteria

Inclusion Criteria

All pediatric patients (0-18yrs) undergoing cardiac catheterization by the participating interventional cardiologist at Phoenix Children's Hospital will be recruited for this investigation

Treatment Details

Interventions

• Near-infrared Spectroscopy (NIRS) Monitor (Procedure)

Who Is Running the Clinical Trial?

Phoenix Children's Hospital

Lead Sponsor

Trials

78

Recruited

5,014,000+

Robert L. Meyer

Phoenix Children's Hospital

Chief Executive Officer since 2003

Bachelor of Business Administration from the University of Michigan

Blake Bulloch

Phoenix Children's Hospital

Chief Medical Officer since 2024

MD, MBA