Water Dosing for Orthostatic Hypotension
Recruiting in Palo Alto (17 mi)
SR
Overseen bySatish R Raj, MD MSCI
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Satish R. Raj
No Placebo Group
Trial Summary
What is the purpose of this trial?
We are studying the effects of oral water ingestion in patients with orthostatic hypotension. In this study, we are testing the null hypothesis that the blood pressure increase with oral water ingestion will not be diminished if a full prior water dose is given a few hours earlier.
Research Team
SR
Satish R Raj, MD MSCI
Principal Investigator
Vanderbilt University Medical Center
Eligibility Criteria
This trial is for adults aged 18-80 with orthostatic hypotension, which means their blood pressure drops significantly when standing up. They should have previously shown a blood pressure increase after drinking water in other studies. Pregnant individuals cannot participate.Inclusion Criteria
I am between 18 and 80 years old.
Your body reacts strongly to drinking water in other research studies.
My blood pressure drops significantly when I stand up.
Exclusion Criteria
Pregnancy
Treatment Details
Interventions
- Water (Other)
Trial OverviewThe study investigates the effect of two different doses of water on blood pressure in patients with orthostatic hypotension. It aims to determine if the pressor (blood-pressure raising) response to water diminishes when a full dose is taken earlier.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: 1Experimental Treatment1 Intervention
16 oz water in AM
Group II: 2Active Control1 Intervention
water 1 oz in AM
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Who Is Running the Clinical Trial?
Satish R. Raj
Lead Sponsor
Trials
7
Recruited
690+