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Behavioural Intervention

AI-Optimized Weight Loss Treatment for Obesity (ReLearn Trial)

N/A

Waitlist Available

Led By Evan M Forman, PhD

Research Sponsored by Drexel University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Individuals must be adults (aged 18-70)

Access and willingness to use an Apple or Android smartphone

Must not have

History of bariatric surgery

Weight loss of > 5% in the previous 3 months

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 1-month, 6-month, and 12-month assessment

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing a smart computer program that helps people lose weight by giving them personalized advice. It tracks their progress and provides the best support based on individual responses. The goal is to see if this method is more effective and cheaper than traditional weight loss coaching.

Who is the study for?

Adults aged 18-70 with a BMI of 27-50 kg/m², able to walk two city blocks and engage in remote weight loss programs using a smartphone. Excludes those with certain medical conditions, recent significant weight loss, or changes in medications affecting weight.

What is being tested?

Project ReLearn is comparing standard behavioral treatment for weight loss against an AI-optimized version that adapts weekly based on participant responses using mobile and wearable tech over one year.

What are the potential side effects?

Since this trial involves non-medical interventions focused on behavior change and monitoring via technology, there are no direct side effects like you'd expect from medication; however, participants may experience stress or fatigue.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 18 and 70 years old.

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I can and will use a smartphone.

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My BMI is between 27 and 50, indicating I am overweight or obese.

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I can walk two city blocks without needing to stop.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I have had weight loss surgery in the past.

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I have lost more than 5% of my weight in the last 3 months.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 1-month, 6-month, and 12-month assessment

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 1-month, 6-month, and 12-month assessment

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 1-month, 6-month, and 12-month assessment for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Costs

Weight change

Secondary study objectives

Acceptability as Measured by Likert Self-report Scale

Calorie intake

Physical Activity

Other study objectives

Autonomous motivation

Binge eating

Depressive symptoms

+1 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: BWL-AIExperimental Treatment1 Intervention

1 year of remote weight loss treatment made up of a combination of (1) remote small group-based behavioral weight loss sessions, (2) 12-minute individual video calls, (2) automated text messages. An MS-level clinician will deliver the group treatment. Most video calls will be delivered by a paraprofessional coach, but some by an MS-level clinician. Each week the AI system will select one of the interventions for each participant based on which treatment the participant has responded to the best, within certain time constraints.

Group II: BWL-SActive Control1 Intervention

1 year of remote gold standard, small group-based behavioral weight loss treatment with an MS-level clinician.

0 / 6Eligibility criteria met