AI-Optimized Weight Loss Treatment for Obesity
(ReLearn Trial)

Recruiting in Palo Alto (17 mi)

Overseen byEvan M Forman, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Drexel University

No Placebo Group

Trial Summary

What is the purpose of this trial?This trial is testing a smart computer program that helps people lose weight by giving them personalized advice. It tracks their progress and provides the best support based on individual responses. The goal is to see if this method is more effective and cheaper than traditional weight loss coaching.

Eligibility Criteria

Adults aged 18-70 with a BMI of 27-50 kg/m², able to walk two city blocks and engage in remote weight loss programs using a smartphone. Excludes those with certain medical conditions, recent significant weight loss, or changes in medications affecting weight.

Inclusion Criteria

I am between 18 and 70 years old.

Individuals must also provide consent for the research team to contact their personal physician if necessary, to provide clearance or to consult about rapid weight loss

I can and will use a smartphone.

+4 more

Exclusion Criteria

I recently started or changed the dose of a medication that may significantly affect my weight.

I have had weight loss surgery in the past.

I have lost more than 5% of my weight in the last 3 months.

+2 more

Participant Groups

Project ReLearn is comparing standard behavioral treatment for weight loss against an AI-optimized version that adapts weekly based on participant responses using mobile and wearable tech over one year.

2Treatment groups

Experimental Treatment

Active Control

Group I: BWL-AIExperimental Treatment1 Intervention

1 year of remote weight loss treatment made up of a combination of (1) remote small group-based behavioral weight loss sessions, (2) 12-minute individual video calls, (2) automated text messages. An MS-level clinician will deliver the group treatment. Most video calls will be delivered by a paraprofessional coach, but some by an MS-level clinician. Each week the AI system will select one of the interventions for each participant based on which treatment the participant has responded to the best, within certain time constraints.

Group II: BWL-SActive Control1 Intervention

1 year of remote gold standard, small group-based behavioral weight loss treatment with an MS-level clinician.