Corneal Cross-linking
Corneal Cross-Linking for Keratoconus
Recruiting0 awardsPhase 1 & 2
Dothan, Alabama
This trial is testing a treatment that uses light and vitamins to strengthen the cornea in people with keratoconus, a condition that makes the cornea thin and cone-shaped. The new treatment option aims to improve the cornea's strength and shape.
Contact Lens
Corneal Gas Permeable Lenses for Keratoconus
Recruiting1 award
Chicago, Illinois
This trial is comparing two methods of correcting vision for people with keratoconus, a condition where the shape of the cornea becomes irregular. The study will compare how well each method works and how satisfied patients are with their vision.
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Trials for Corneal Ectasia Patients
Procedure
Corneal Cross-Linking for Keratoconus
Recruiting1 awardPhase 2
San Francisco, California
This trial is testing a device called the PXL Platinum 330 system, which uses a special light treatment to strengthen the cornea. It targets patients with conditions that weaken and misshape the cornea, such as progressive keratoconus and pellucid marginal degeneration. The treatment works by creating new connections between the fibers in the cornea, helping it stay strong and maintain its shape.
Crosslinking Agent
Standard vs. Accelerated Corneal Crosslinking for Keratoconus
Recruiting2 awardsPhase 2 & 3
Indianapolis, Indiana
This trial compares two methods of corneal crosslinking, a procedure that strengthens the cornea using special eye drops and light. It targets people with progressive keratoconus or corneal ectasia, conditions where the cornea weakens and bulges out. The treatment aims to make the cornea more stable and prevent further vision problems. Corneal crosslinking (CXL) has become the standard treatment for rapidly progressing keratoconus.
Procedure
Corneal Collagen Crosslinking for Keratoconus
Recruiting2 awardsPhase 3
Teaneck, New Jersey
This trial is testing a treatment that uses UV light and vitamin B2 to strengthen weak or misshapen corneas in patients with keratoconus or post-surgery ectasia. The treatment works by creating new bonds in the cornea, making it more stable. This method has been widely adopted and refined to treat progressive keratoconus by increasing the strength of the cornea.
Procedure
Corneal Collagen Crosslinking + Intacs for Keratoconus
Recruiting2 awardsPhase 3
Teaneck, New Jersey
This trial will compare two procedures for treating keratoconus, a degenerative eye disease. One procedure uses a collagen crosslinking, while the other uses Intacs. The goal is to determine which procedure is more effective.
Phase 3 Trials
Crosslinking Agent
Standard vs. Accelerated Corneal Crosslinking for Keratoconus
Recruiting2 awardsPhase 2 & 3
Indianapolis, Indiana
This trial compares two methods of corneal crosslinking, a procedure that strengthens the cornea using special eye drops and light. It targets people with progressive keratoconus or corneal ectasia, conditions where the cornea weakens and bulges out. The treatment aims to make the cornea more stable and prevent further vision problems. Corneal crosslinking (CXL) has become the standard treatment for rapidly progressing keratoconus.
Procedure
Corneal Collagen Crosslinking for Keratoconus
Recruiting2 awardsPhase 3
Teaneck, New Jersey
This trial is testing a treatment that uses UV light and vitamin B2 to strengthen weak or misshapen corneas in patients with keratoconus or post-surgery ectasia. The treatment works by creating new bonds in the cornea, making it more stable. This method has been widely adopted and refined to treat progressive keratoconus by increasing the strength of the cornea.
Procedure
Corneal Collagen Crosslinking + Intacs for Keratoconus
Recruiting2 awardsPhase 3
Teaneck, New Jersey
This trial will compare two procedures for treating keratoconus, a degenerative eye disease. One procedure uses a collagen crosslinking, while the other uses Intacs. The goal is to determine which procedure is more effective.
Trials With No Placebo
Procedure
Corneal Cross-Linking for Keratoconus
Recruiting1 awardPhase 2
San Francisco, California
This trial is testing a device called the PXL Platinum 330 system, which uses a special light treatment to strengthen the cornea. It targets patients with conditions that weaken and misshape the cornea, such as progressive keratoconus and pellucid marginal degeneration. The treatment works by creating new connections between the fibers in the cornea, helping it stay strong and maintain its shape.
Crosslinking Agent
Standard vs. Accelerated Corneal Crosslinking for Keratoconus
Recruiting2 awardsPhase 2 & 3
Indianapolis, Indiana
This trial compares two methods of corneal crosslinking, a procedure that strengthens the cornea using special eye drops and light. It targets people with progressive keratoconus or corneal ectasia, conditions where the cornea weakens and bulges out. The treatment aims to make the cornea more stable and prevent further vision problems. Corneal crosslinking (CXL) has become the standard treatment for rapidly progressing keratoconus.
Vitamin
Riboflavin for Keratoconus
Recruiting1 award1 criteria
Columbia, Missouri
This trial tests if taking vitamin B2 pills and spending time in the sun can help strengthen the cornea in patients with certain eye conditions. The goal is to provide a less painful and cheaper alternative to current treatments. A method using vitamin B2 and sunlight has been developed since the late 1990s to strengthen the cornea in these conditions.
Corneal Implant
Intacs Inserts for Keratoconus
Recruiting1 award5 criteria
Dallas, Texas
This trial is for a device that corrects nearsightedness and keratoconus. The device is made of two clear segments from a biomedical material called polymethylmethacrylate, and is available in three thicknesses. Two INTACS inserts may be implanted depending on the orientation of the cone and the amount of myopia and astigmatism to be reduced.
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.