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Plasma Tear Drops for Dry Eye Syndrome

N/A
Waitlist Available
Research Sponsored by University of Rochester
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to 3 months
Awards & highlights
No Placebo-Only Group

Summary

This trial will test whether using plasma tears can improve dry eye symptoms in patients. There will be two groups who will either receive plasma tears with platelets or without.

Who is the study for?
This trial is for individuals with clinically significant dry eye who have no other active eye diseases or allergies. Participants must not be using any eye medications two weeks prior to joining, meet blood donation criteria, and agree to follow the study's instructions. Pregnant individuals or those on antibiotics are excluded.
What is being tested?
The study is testing if Platelet Rich Plasma (PRP) Drops can improve dry eyes compared to Platelet Poor Plasma Drops. It's a double-masked trial at Flaum Eye Institute where neither participants nor researchers know who receives which type of drop until after the results are collected.
What are the potential side effects?
Potential side effects may include discomfort at the site of blood draw for plasma donation and possible irritation from the drops themselves, although specific side effects related to PRP drops will be monitored throughout the study.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to 3 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 3 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Mean change in acuity
Mean change in breakup pattern to appear
Mean change in consistency of lipid compensation
+2 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Platelet Rich Plasma TearsExperimental Treatment1 Intervention
Group II: Platelet Poor Plasma TearActive Control1 Intervention

Find a Location

Who is running the clinical trial?

University of RochesterLead Sponsor
867 Previous Clinical Trials
548,867 Total Patients Enrolled

Media Library

Platelet Poor Plasma Tear Drops (Other) Clinical Trial Eligibility Overview. Trial Name: NCT05121493 — N/A
Dry Eye Syndrome Research Study Groups: Platelet Poor Plasma Tear, Platelet Rich Plasma Tears
Dry Eye Syndrome Clinical Trial 2023: Platelet Poor Plasma Tear Drops Highlights & Side Effects. Trial Name: NCT05121493 — N/A
Platelet Poor Plasma Tear Drops (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05121493 — N/A
~10 spots leftby Dec 2025