Popular Trials
Device
Adaptive DBS for Obsessive-Compulsive Disorder
This trial is for people with OCD who have not responded to other treatments. The goal is to use signals from the brain to automatically adjust the Deep Brain Stimulation (DBS) stimulation factors to improve symptom management and reduce stimulation-induced behavioral side effects.
NMDA Receptor Antagonist
Ketamine for Obsessive-Compulsive Disorder
This trial aims to understand how ketamine quickly improves symptoms in people with Obsessive-Compulsive Disorder (OCD). Ketamine works by blocking a specific brain receptor, which helps reduce repetitive thoughts and behaviors. Recent research demonstrated that ketamine rapidly reduces OCD symptoms. The study focuses on how this process happens at different levels in the brain.
Behavioural Intervention
Brain Stimulation for Obsessive-Compulsive Disorder
This trial is looking for better ways to treat OCD by identifying abnormal brain signals associated with the disorder and psychiatric symptoms, and investigating whether novel therapeutic stimulation sites can help improve OCD symptoms.
Behavioural Intervention
Mindfulness-Based Interventions for Obsessive-Compulsive Disorder
This trial is testing a new treatment called Mindfulness-Based Cognitive Therapy (MBCT) for people with Obsessive-Compulsive Disorder (OCD) who haven't fully benefited from standard treatments. MBCT helps patients become more aware of their thoughts and feelings without reacting to them, which can reduce OCD symptoms. If successful, this approach could be used widely in clinical settings to help more people with OCD. Mindfulness-Based Cognitive Therapy (MBCT) has been shown to be effective in various mental disorders and is now being explored as a complementary treatment for OCD, particularly for those who do not fully benefit from standard treatments.
Popular Filters
Trials for Hoarding Disorder Patients
Deep Brain Stimulation
Deep Brain Stimulation for Obsessive-Compulsive Disorder
This trial is for people with a hard-to-control form of OCD. The goal is to find a more reliable system for treating OCD by studying how to best place electrodes in the brain to deliver electrical stimulation.
Selective Serotonin Reuptake Inhibitor
Fluoxetine for Obsessive-Compulsive Disorder
This trial uses brain scans and fluoxetine to treat unmedicated OCD patients. It aims to see how the brain changes with treatment and identify markers that predict treatment success. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), has been used for many years to treat obsessive-compulsive disorder (OCD) and is recognized for its efficacy in reducing both obsessions and compulsions.
Behavioral Intervention
Exposure Therapy for Child Anxiety
This trial will compare the effectiveness of three different types of treatment for anxiety disorders in children and adolescents. The three types of treatment are cognitive behavioral therapy with exposure (CBT), patient-centered telehealth CBT (PCT-CBT; patient-centered telehealth closed as of 5/1/21), and traditional outpatient CBT. The trial will involve 379 participants who will be randomly assigned to one of the three treatment groups. The primary outcome measures will be the changes in the participants' anxiety symptoms, functioning, and quality of life from baseline to follow-up.
Trials for Obsessive-Compulsive Disorder Patients
Deep Brain Stimulation
Deep Brain Stimulation for Obsessive-Compulsive Disorder
This trial is for people with a hard-to-control form of OCD. The goal is to find a more reliable system for treating OCD by studying how to best place electrodes in the brain to deliver electrical stimulation.
Selective Serotonin Reuptake Inhibitor
Fluoxetine for Obsessive-Compulsive Disorder
This trial uses brain scans and fluoxetine to treat unmedicated OCD patients. It aims to see how the brain changes with treatment and identify markers that predict treatment success. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), has been used for many years to treat obsessive-compulsive disorder (OCD) and is recognized for its efficacy in reducing both obsessions and compulsions.
Behavioral Intervention
Exposure Therapy for Child Anxiety
This trial will compare the effectiveness of three different types of treatment for anxiety disorders in children and adolescents. The three types of treatment are cognitive behavioral therapy with exposure (CBT), patient-centered telehealth CBT (PCT-CBT; patient-centered telehealth closed as of 5/1/21), and traditional outpatient CBT. The trial will involve 379 participants who will be randomly assigned to one of the three treatment groups. The primary outcome measures will be the changes in the participants' anxiety symptoms, functioning, and quality of life from baseline to follow-up.
Trials With No Placebo
Deep Brain Stimulation
Deep Brain Stimulation for Obsessive-Compulsive Disorder
This trial is for people with a hard-to-control form of OCD. The goal is to find a more reliable system for treating OCD by studying how to best place electrodes in the brain to deliver electrical stimulation.
Selective Serotonin Reuptake Inhibitor
Fluoxetine for Obsessive-Compulsive Disorder
This trial uses brain scans and fluoxetine to treat unmedicated OCD patients. It aims to see how the brain changes with treatment and identify markers that predict treatment success. Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), has been used for many years to treat obsessive-compulsive disorder (OCD) and is recognized for its efficacy in reducing both obsessions and compulsions.
Behavioral Intervention
Exposure Therapy for Child Anxiety
This trial will compare the effectiveness of three different types of treatment for anxiety disorders in children and adolescents. The three types of treatment are cognitive behavioral therapy with exposure (CBT), patient-centered telehealth CBT (PCT-CBT; patient-centered telehealth closed as of 5/1/21), and traditional outpatient CBT. The trial will involve 379 participants who will be randomly assigned to one of the three treatment groups. The primary outcome measures will be the changes in the participants' anxiety symptoms, functioning, and quality of life from baseline to follow-up.
View More Related Trials
Frequently Asked Questions
Introduction to obsessive compulsive disorder
What are the top hospitals conducting obsessive compulsive disorder research?
Obsessive-compulsive disorder (OCD) is a mental health condition that affects millions of people worldwide, causing persistent and intrusive thoughts, as well as repetitive behaviors. In the quest to find effective treatments for OCD, several top hospitals have emerged as leaders in conducting clinical trials. Massachusetts General Hospital in Boston heads this list with an impressive 10 ongoing trials dedicated to OCD and a noteworthy history of 19 previous studies since their first recorded trial in 2003. Baylor College of Medicine in Houston follows closely behind with seven active OCD trials and a total of 17 completed trials since embarking on their research journey in this area back in 2017.
Stanford University, nestled within the vibrant community of Stanford, California, is also making significant strides towards better understanding and treating OCD. Their researchers are currently engaged in six active clinical trials related to OCD while having conducted nine previous studies since recording their first trial just five years ago in 2016. Meanwhile, McLean Hospital located in Belmont, Massachusetts boasts five active OCD trials and has contributed valuable insights through seven completed studies since initiating its inaugural obsessive-compulsive disorder trial back in 2011.
Additionally adding itself to this list is Brown University situated amidst the quaint charm of Providence, Rhode island; although smaller-scale compared to other institutions mentioned here , it plays no less important role by actively participating three current obsessive-compulsive disorder clinical trials thus far contributing positively towards accumulating overall knowledge base relative to such cases.Their contribution can be traced quite recently starting from only three years ago-2018 .
These leading hospitals represent beacons of hope for individuals living with OCD by tirelessly pursuing innovative approaches that could potentially transform lives. The dedication shown by these institutions underscores the urgency and importance placed upon furthering our understanding of this complex mental health condition. With each new study they undertake or breakthrough they achieve along the way - patients' prospects shine brighter as we continue striving towards improved treatment options for those impacted by OCD.
Which are the best cities for obsessive compulsive disorder clinical trials?
When it comes to obsessive-compulsive disorder (OCD) clinical trials, several cities stand out as leaders in research and development. Boston, Massachusetts leads the pack with 16 active trials focusing on promising treatments like Troriluzole, Selpercatinib, and BX Pulsar 1002. New york, New York follows closely behind with 12 ongoing studies exploring similar interventions such as Troriluzole and Selpercatinib. Additionally, Houston, Texas; Miami, Florida; and Chicago Illinois each offer 10 active trials investigating various treatment options for OCD. These cities provide individuals with access to cutting-edge clinical trials that have the potential to advance our understanding and improve management of this challenging condition.
Which are the top treatments for obsessive compulsive disorder being explored in clinical trials?
Obsessive compulsive disorder (OCD) research is actively investigating various treatments to help individuals struggling with this condition. Troriluzole, a promising contender, is currently being explored in three ongoing clinical trials for OCD. Since its initial listing in 2017, it has accumulated a total of three trials dedicated specifically to OCD patients. Another treatment option under investigation is active stimulation, which has shown potential in one active trial and holds promise as an intervention for OCD since first appearing on the scene in 2017. These advancements bring hope for improved quality of life and relief from the burdensome symptoms of OCD.
What are the most recent clinical trials for obsessive compulsive disorder?
Exciting advancements in the treatment of obsessive-compulsive disorder (OCD) are emerging through recent clinical trials. Psilocybin, a compound found in certain mushrooms, is being investigated for its potential therapeutic effects on OCD symptoms. Initial findings from Phase 1 trials have shown promising results. Another trial involves Tolcapone, a medication typically used to treat Parkinson's disease but now being explored as a potential treatment for OCD. Additionally, researchers are exploring the efficacy of FMT capsules combined with SIMBA capsules to alleviate OCD symptoms in Phase 2 trials. These innovative studies provide hope for individuals living with OCD and offer prospects for improved management and well-being.
What obsessive compulsive disorder clinical trials were recently completed?
A recent clinical trial investigating treatment options for obsessive-compulsive disorder (OCD) has concluded with promising results. In January 2019, the University of Arizona completed a trial evaluating the effectiveness of Psilocybin at a dosage of 300 mcg/kg. This study provides valuable insights into potential therapeutic approaches for individuals living with OCD and highlights ongoing efforts to find innovative solutions for this challenging mental health condition.