Dr. Scott Irwin, MD, PhD
Claim this profileCedars-Sinai Health System
Studies Pancreatic Cancer
Studies Major Depression
3 reported clinical trials
4 drugs studied
Area of expertise
1Pancreatic Cancer
2Major Depression
Stage I
Stage II
Stage III
Affiliated Hospitals
Clinical Trials Scott Irwin, MD, PhD is currently running
Oral Ketamine
for Anxiety in Pancreatic Cancer Patients
This is a prospective, single center, double blind, randomized, crossover feasibility study of oral ketamine versus placebo for the treatment of anxiety in patients with pancreatic cancer currently receiving or within 12 weeks of receiving cancer targeted therapy. The primary objective is to determine the feasibility of enrolling subjects and treatment adherence. The secondary objectives are to describe the safety and tolerability. Exploratory objectives are to assess the effect of ketamine/placebo on Depression, Anxiety, Physical Function, Pain Interference, Pain Intensity, Fatigue, Sleep Disturbance, and Ability to Participate in Social Roles and Activities as measured by PROMIS Anxiety Short Form 7a and the PROMIS-29 Profile v2.1 of Patient Reported Outcomes, as well as changes in circulatory inflammatory cytokines, blood glutamine levels, and other biomarkers of anxiety and/or depression.
Recruiting0 awards Phase < 111 criteria
Virtual Reality Therapy
for Gastrointestinal Cancer Pain
Patients with digestive tract malignancy often experience severe and unremitting abdominal pain that negatively affects physical, emotional, and social function, as well as health related quality of life (HRQOL). Therapeutic virtual reality (VR) has emerged as a promising and evidence-based treatment modality for cancer pain. Users of VR wear a pair of goggles with a close-proximity screen in front of the eyes that creates a sensation of being transported into lifelike, three-dimensional worlds. To date, VR has been limited to short-term clinical trials for cancer pain. Moreover, limited research exists on theory-based VR modalities beyond mere distraction, such as VR that employs acceptance and commitment therapy (ACT) with components of biofeedback and mindfulness. To bridge these gaps, this study seeks to: (1) assess the impact of immersive VR on patient-reported outcomes (PROs), including pain, activity metrics, and opioid use among patients with visceral pain from a digestive tract malignancy; (2) assess differences in PROs, activity metrics, and opioid use between skills-based VR therapy vs. distraction VR therapy; and (3) determine patient-level predictors of VR treatment response in visceral cancer pain. To address these aims, the study will measure PROs and opioid use in 360 patients randomized among 3 groups and follow them for 60 days after enrollment: (1) an enhanced VR group receiving skills-based VR; (2) a distraction-based VR group receiving patient-selected VR videos; and (3) a VR sham control group using a VR headset with 2-D content. The results will inform best practices for the implementation of VR for visceral cancer pain management and guide selection of patient-tailored experiences.
Recruiting0 awards N/A4 criteria
More about Scott Irwin, MD, PhD
Clinical Trial Related2 years of experience running clinical trials · Led 3 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Scott Irwin, MD, PhD has experience with
- PDC-1421 Capsule
- Virtual Reality
- Ketamine
- Placebo
Breakdown of trials Scott Irwin, MD, PhD has run
Pancreatic Cancer
Major Depression
Major Depressive Disorder
Cancer-Associated Pain
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Scott Irwin, MD, PhD specialize in?
Scott Irwin, MD, PhD focuses on Pancreatic Cancer and Major Depression. In particular, much of their work with Pancreatic Cancer has involved treating patients, or patients who are undergoing treatment.
Is Scott Irwin, MD, PhD currently recruiting for clinical trials?
Yes, Scott Irwin, MD, PhD is currently recruiting for 2 clinical trials in Los Angeles California. If you're interested in participating, you should apply.
Are there any treatments that Scott Irwin, MD, PhD has studied deeply?
Yes, Scott Irwin, MD, PhD has studied treatments such as PDC-1421 Capsule, Virtual Reality, Ketamine.
What is the best way to schedule an appointment with Scott Irwin, MD, PhD?
Apply for one of the trials that Scott Irwin, MD, PhD is conducting.
What is the office address of Scott Irwin, MD, PhD?
The office of Scott Irwin, MD, PhD is located at: Cedars-Sinai Health System, Los Angeles, California 90048 United States. This is the address for their practice at the Cedars-Sinai Health System.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.