Aristospan

Macular Edema, Stomatitis, Denture, Ophthalmia, Sympathetic + 113 more

Treatment

16 FDA approvals

20 Active Studies for Aristospan

Treatment for

Macular Edema

What is Aristospan

Triamcinolone

The Generic name of this drug

Treatment Summary

Triamcinolone is a steroid medication used to treat inflammatory conditions, allergies, and pain. It is available in various forms such as triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate. It was approved by the FDA in 1957 and a suspension of triamcinolone acetonide was recently approved for suprachoroidal injection for the treatment of macular edema associated with uveitis in October 2021.

Aristocort

is the brand name

image of different drug pills on a surface

Aristospan Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Aristocort

Triamcinolone

1961

532

Approved as Treatment by the FDA

Triamcinolone, also called Aristocort, is approved by the FDA for 16 uses which include Lichen Planus and Ganglia .

Lichen Planus

Helps manage Lichen Planus (LP)

Ganglia

Helps manage cystic tumour of the ganglia

Granuloma Annulare

Helps manage granuloma annulare lesions

Psoriasis

Helps manage Psoriatic plaque

Neurodermatitis

Helps manage Lichen simplex chronicus

Lupus Erythematosus, Discoid

Helps manage Discoid Lupus Erythematosus (DLE)

granuloma annulare lesions

Helps manage granuloma annulare lesions

cystic tumour of the ganglia

Helps manage cystic tumour of the ganglia

Lichen simplex chronicus

Helps manage Lichen simplex chronicus

Lichen Planus (LP)

Helps manage Lichen Planus (LP)

Discoid Lupus Erythematosus (DLE)

Helps manage Discoid Lupus Erythematosus (DLE)

Alopecia Areata (AA)

Helps manage Alopecia Areata (AA)

Keloids Scars

Helps manage Keloids Scars

Necrobiosis Lipoidica

Helps manage Necrobiosis lipoidica diabeticorum

Alopecia Areata

Helps manage Alopecia Areata (AA)

Psoriatic plaque

Helps manage Psoriatic plaque

Effectiveness

How Aristospan Affects Patients

Triamcinolone is a type of medication used to reduce inflammation in many parts of the body. It should not be given as an injection into the spine.

How Aristospan works in the body

Triamcinolone is an anti-inflammatory corticosteroid. It works by preventing the breakdown of certain cell membranes, stopping the formation of certain fatty acids, and suppressing pro-inflammatory signals. This reduces swelling, redness, and other signs of inflammation.

When to interrupt dosage

The prescribed amount of Aristospan is contingent upon the diagnosed condition, including Mycosis Fungoides (MF), Mycoses and Alopecia Areata (AA). Dosage fluctuates as per the administration system (e.g. Ointment or Injection, suspension - Intralesional; Parenteral) depicted in the following table.

Condition

Dosage

Administration

Neurodermatitis

, 40.0 mg/mL, 10.0 mg/mL, 0.055 mg, 0.001 mg/mg, 0.25 mg/mL, 1.0 mg/mL, 0.0005 mg/mg, 0.00025 mg/mg, 0.005 mg/mg, 5.0 mg/mL, 20.0 mg/mL, 0.000147 mg/mg, 0.5 mg/mL, 40.0 mg, 1.0 mg, 0.000025 mg/mg, 0.1 %, 0.025 %, 5.0 mg, 0.25 mg, 2.0 mg, 4.0 mg, 0.5 %, 15.0 mg/mL, 6.5 mg, 80.0 mg/mL, 0.075 mg, 200.0 mg/mL, 32.0 mg, 0.055 mg/dose, 0.5 mg, 0.2 mg/pump actuation, 0.1 mg/dose, 25.0 mg/mL, 0.055 mg/pump actuation, 2.0 mg/mL, 0.4 mg/mL

Injection, suspension, Intra-articular; Intramuscular, Injection, suspension - Intra-articular; Intramuscular, , Injection, suspension - Intra-articular; Intralesional, Intra-articular; Intralesional, Spray, metered, Nasal, Spray, metered - Nasal, Lotion, Lotion - Topical, Ointment - Topical, Topical, Ointment, Cream, Cream - Topical, Injection, suspension - Intralesional; Parenteral, Intra-articular; Parenteral, Injection, suspension - Intra-articular; Parenteral, Intralesional; Parenteral, Intra-articular; Intrabursal; Intradermal; Intralesional, Injection, suspension - Intra-articular; Intrabursal; Intradermal; Intralesional, Aerosol, spray, Aerosol, spray - Topical, Paste - Topical, Paste, Kit, Injection, suspension - Intramuscular, Intramuscular, Dental, Paste - Dental, Suspension - Intra-articular; Intramuscular, Suspension - Intra-articular; Intrabursal; Intradermal; Intrasynovial, Suspension, Aerosol, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Oral, Tablet, Tablet - Oral, Intra-articular; Intramuscular; Intrasynovial, Liquid - Intra-articular; Intramuscular; Intrasynovial, Intra-articular; Intradermal; Intramuscular, Syrup - Oral, Syrup, Suspension - Intramuscular, Liquid, Liquid - Intra-articular; Intradermal; Intramuscular, Spray, suspension - Nasal, Injection, solution, Injection, solution - Intra-articular; Intramuscular, Kit - Epidural; Infiltration; Intra-articular; Intramuscular; Topical, Epidural; Infiltration; Intra-articular; Intramuscular; Topical, Ophthalmic, Injection, suspension - Ophthalmic, Intravitreal, Intra-articular; Intrabursal; Intradermal; Intrasynovial, Suspension - Intra-articular; Intrabursal; Intramuscular, Intra-articular; Intrabursal; Intramuscular, Intralesional, Suspension - Intralesional, Respiratory (inhalation), Intra-articular, Suspension - Intra-articular, Intra-articular; Intradermal; Intralesional; Intramuscular, Suspension - Intra-articular; Intradermal; Intralesional; Intramuscular, Suspension - Intravitreal, Infiltration; Intra-articular; Intramuscular; Respiratory (inhalation); Topical, Kit - Infiltration; Intra-articular; Intramuscular; Respiratory (inhalation); Topical, Spray - Topical, Spray, Intra-articular; Intrasynovial; Periarticular, Suspension - Intra-articular; Intrasynovial; Periarticular, Kit - Intra-articular; Intramuscular, Suspension - Ophthalmic, Subcutaneous, Implant - Subcutaneous, Implant, Intra-articular; Intramuscular; Intravitreal, Injection, suspension - Intra-articular; Intramuscular; Intravitreal, Epidural; Infiltration; Intra-articular; Intramuscular, Kit - Epidural; Infiltration; Intra-articular; Intramuscular, Kit - Epidural; Intra-articular; Intramuscular; Topical, Epidural; Intra-articular; Intramuscular; Topical, Injection, suspension - Intra-articular; Intralesional; Intramuscular; Intrasynovial; Parenteral, Epidural; Infiltration; Intra-articular; Intralesional, Kit - Epidural; Infiltration; Intra-articular; Intralesional, Kit - Intra-articular, Paste, dentifrice - Dental, Paste, dentifrice, Intra-articular; Intralesional; Intramuscular; Intrasynovial; Parenteral, Kit - Infiltration; Soft tissue; Topical, Infiltration; Soft tissue; Topical, Ointment - Buccal, Buccal, Emulsion, Gel, Gel - Topical, Emulsion - Topical, Kit - Topical, Intra-articular; Intramuscular; Topical, Infiltration; Intra-articular; Intramuscular; Topical, Kit - Infiltration; Intra-articular; Intramuscular; Topical, Injection, suspension - Intra-articular

Itching of the Anus

Thrombocytopenia

Craniotomy

Dermatomyositis

Stomatitis, Denture

Multiple Sclerosis

Inflammation

Uveitis

Hypercalcemia

Hives

Berylliosis

Vitrectomy therapy

Skin Diseases

Intertrigo

Proteinuria

Tenosynovitis

Addison Disease

Ganglia

Atopic Dermatitis

Warnings

Aristospan has four contraindications, and it should not be taken with any of the situations described in the following table.

Aristospan Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Triamcinolone may interact with Pulse Frequency

Mycoses

Do Not Combine

active periocular infections

Do Not Combine

Eye Infections

Do Not Combine

There are 20 known major drug interactions with Aristospan.

Common Aristospan Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Triamcinolone.

Abetimus

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with Abetimus.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Triamcinolone.

Aristospan Toxicity & Overdose Risk

The lowest toxic dose of triamcinolone acetonide in rats is 13,100µg/kg and in mice is 132mg/kg. The lowest toxic dose of triamcinolone acetonide in rats when taken orally is 1451mg/kg and in mice is 2168mg/kg. When administered intraperitoneally in mice, the lowest toxic dose is 105mg/kg. Overdosing on triamcinolone acetonide may lead to Cushing's syndrome, which can be treated with supportive care and mifepristone.

Aristospan Novel Uses: Which Conditions Have a Clinical Trial Featuring Aristospan?

1076 clinical trials are currently evaluating the potential of Aristospan to ameliorate Lupus, Atopic Dermatitis and Brain Metastases.

Condition

Clinical Trials

Trial Phases

Macular Edema

1 Actively Recruiting

Phase 2

Asthma

86 Actively Recruiting

Phase 1, Phase 4, Early Phase 1, Not Applicable, Phase 2, Phase 3

Anemia, Hemolytic, Autoimmune

0 Actively Recruiting

Rheumatoid Arthritis

58 Actively Recruiting

Not Applicable, Phase 3, Phase 2, Phase 1, Phase 4

Vitrectomy therapy

0 Actively Recruiting

Dermatitis, Seborrheic

0 Actively Recruiting

Crohn's Disease

53 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4, Early Phase 1

Inflammation

56 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 3, Phase 4

Thyroiditis

0 Actively Recruiting

Brain

0 Actively Recruiting

Stomatitis

0 Actively Recruiting

Dermatitis

0 Actively Recruiting

Tinea

0 Actively Recruiting

Conjunctivitis, Bacterial

0 Actively Recruiting

Tenosynovitis

0 Actively Recruiting

Mycoses

0 Actively Recruiting

Synovitis

1 Actively Recruiting

Phase 4

Dermatitis, Allergic Contact

0 Actively Recruiting

Keloids Scars

1 Actively Recruiting

Phase 3

Ulcer

0 Actively Recruiting

Aristospan Reviews: What are patients saying about Aristospan?

3.3

Patient Review

2/17/2011

Aristospan for Disease in which Body has Immune Response Against Itself

I've had this medication injected into my knees every three months for nearly a year, and it has really helped to lessen the pain and keep me mobile. I've also had injections in my thumbs for severe arthritis pain, which completely took away the pain for eight months.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about aristospan

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Aristospan available in the US?

"The U.S. approved product, Aristospan®, is available as a 1 mL vial with a total strength of 20 mg/mL. The imported product does not have a barcode."

Answered by AI

What is triamcinolone acetonide Injection?

"This injection contains a corticosteroid called triamcinolone, which is used to treat inflammation, allergic reactions, arthritis, gout, skin diseases, and many other medical problems. It is given to patients who are unable to take medicines by mouth."

Answered by AI

Is Aristospan discontinued?

"As of September 2020, Sandoz has stopped selling Aristospan."

Answered by AI

What is triamcinolone 5mg?

"Aristospan Injection 5 is a prescription medicine used to treat symptoms of inflammatory conditions such as severe allergic reactions, skin disorders, severe colitis, inflammation of joints or tendons, blood cell disorders, inflammatory eye disorders, lung disorders, and problems caused by low adrenal gland."

Answered by AI