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What is Theolair
TheophyllineThe Generic name of this drug
Treatment SummaryTheophylline is a medication derived from tea and used to treat asthma, bronchospasm, and COPD. It works by inhibiting phosphodiesterase, blocking adenosine receptors, and activating histone deacetylase. Theophylline is sold under the brand names Uniphyl and Theochron.
Elixophyllinis the brand name
Theolair Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Elixophyllin
Theophylline
1979
114
Approved as Treatment by the FDA
Theophylline, commonly known as Elixophyllin, is approved by the FDA for 4 uses like Asthma and Bronchitis, Chronic .Asthma
Bronchitis, Chronic
Bronchoconstriction
Lung Diseases
Effectiveness
How Theolair Affects PatientsTheophylline is similar to caffeine and theobromine and is used to treat asthma and other respiratory problems. It helps open up the airways to make breathing easier, as well as reduces the body's sensitivity to triggers that can cause airway spasms.
How Theolair works in the bodyTheophylline works to relax the muscles around the airways and lungs, allowing them to open up and making it easier to breathe. It does this by inhibiting a specific enzyme that breaks down a compound important for muscle contraction. Additionally, theophylline binds to a receptor that helps stop inflammation, which can make breathing harder.
When to interrupt dosage
The proscribed dosage of Theolair is contingent upon the diagnosed issue, for example Bronchodilation, Bronchoconstriction and Chronic Obstructive Pulmonary Disease (COPD). The measure of dosage shifts, contingent upon the technique of delivery, as indicated in the table beneath.Condition
Dosage
Administration
Airway secretion clearance therapy
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Chronic Obstructive Pulmonary Disease
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Acute Bronchitis
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchial Spasm
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchitis, Chronic
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Asthma
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Emphysema
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchoconstriction
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Lung Diseases
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchodilation
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Bronchitis, Chronic
, 8.0 mg/mL, 0.8 mg/mL, 1.6 mg/mL, 300.0 mg, 200.0 mg, 100.0 mg, 400.0 mg, 450.0 mg, 600.0 mg, 50.0 mg, 250.0 mg, 500.0 mg, 125.0 mg, 70.0 mg, 140.0 mg, 118.0 mg, 2.0 mg/mL, 4.0 mg/mL, 3.2 mg/mL, 175.0 mg, 65.0 mg, 75.0 mg, 350.0 mg, 130.0 mg, 0.4 mg/mL, 7.0 mg/mL
, Oral, Solution, Solution - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, extended release, Tablet, extended release - Oral, Liquid, Liquid - Oral, Tablet, Tablet - Oral, Capsule, extended release, Capsule, extended release - Oral, Kit, Elixir, Elixir - Oral, Syrup, Syrup - Oral, Capsule - Oral, Capsule, Injection, Injection - Intravenous, Solution - Intravenous
Warnings
There are 20 known major drug interactions with Theolair.Common Theolair Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Theophylline.
Aminophylline
Major
The metabolism of Aminophylline can be decreased when combined with Theophylline.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Theophylline.
Bendamustine
Major
The metabolism of Bendamustine can be decreased when combined with Theophylline.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Theophylline.
Theolair Toxicity & Overdose RiskOverdosing on this drug can cause seizures, abnormal heart rhythms, and gastrointestinal effects.
Theolair Novel Uses: Which Conditions Have a Clinical Trial Featuring Theolair?
280 active clinical trials are currently being conducted to assess the efficacy of Theolair in providing Bronchodilation, relieving Chronic Bronchitis and controlling Asthma.Condition
Clinical Trials
Trial Phases
Asthma
104 Actively Recruiting
Phase 4, Not Applicable, Early Phase 1, Phase 2, Phase 3, Phase 1
Chronic Obstructive Pulmonary Disease
90 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4
Airway secretion clearance therapy
0 Actively Recruiting
Bronchoconstriction
0 Actively Recruiting
Bronchodilation
0 Actively Recruiting
Emphysema
7 Actively Recruiting
Phase 4, Not Applicable, Phase 2
Bronchitis, Chronic
1 Actively Recruiting
Not Applicable
Acute Bronchitis
2 Actively Recruiting
Not Applicable
Bronchitis, Chronic
0 Actively Recruiting
Lung Diseases
9 Actively Recruiting
Not Applicable, Phase 1, Phase 2
Bronchial Spasm
1 Actively Recruiting
Phase 2
Theolair Reviews: What are patients saying about Theolair?
4Patient Review
11/15/2009 Though the effects of this medication are speedy and helpful, I have found the side effects to be very off-putting. In particular, the sudden outbursts of anger and frustration have been difficult to deal with.
Patient Q&A Section about theolair
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the side effect of theophylline?
"These are some of the side effects that may occur: nausea/vomiting, stomach/abdominal pain, headache, trouble sleeping, diarrhea, irritability, restlessness, nervousness, shaking, or increased urination."
Answered by AI
What is Theolair prescribed for?
"The drug must be taken regularly to prevent wheezing and shortness of breath. It works by relaxing the muscles around the airways so that they open up and the person can breathe more easily. The drug also decreases the lungs' response to irritants."
Answered by AI
Why is theophylline no longer used?
"While oral theophylline was once used as a bronchodilator to treat chronic obstructive pulmonary disease (COPD), it is no longer favored due to the side effects that come with higher doses and the advancement of improved drug treatments."
Answered by AI