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What is Zetonna
CiclesonideThe Generic name of this drug
Treatment SummaryCiclesonide, sold under the brand name Alvesco, is a type of steroid medicine used to treat breathing problems caused by obstructive airway diseases.
Omnarisis the brand name
Zetonna Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Omnaris
Ciclesonide
2008
15
Effectiveness
How Zetonna Affects PatientsCiclesonide is a type of drug that is changed into a different, active form when it is used in the nose. This active form (called des-ciclesonide) is very good at reducing inflammation and has an effect 120 times stronger than the original drug. It's not clear exactly how ciclesonide works to reduce symptoms of allergic rhinitis, but it's thought to work by affecting different types of cells and molecules involved in allergic inflammation.
How Zetonna works in the bodyCiclesonide is a type of glucocorticoid that helps fight inflammation. It does this by limiting the expansion of blood vessels and decreasing the number of white blood cells in the area. It also stops certain compounds from forming which cause inflammation. Ciclesonide works by binding to a receptor in the cell nucleus and changing the expression of certain genes. This includes reducing the production of a compound called interlukin 2, which leads to more inflammation.
When to interrupt dosage
The proposed measure of Zetonna is reliant upon the diagnosed condition, including Perennial Allergic Rhinitis (PAR), Hay Fever and Bronchoconstriction. The amount of dosage depends on the technique of delivery (e.g. Aerosol, metered - Respiratory (inhalation) or Aerosol, metered) outlined in the table underneath.Condition
Dosage
Administration
Asthma
0.05 mg, , 0.08 mg, 0.16 mg, 0.037 mg, 0.05 mg/pump actuation, 0.1 mg/pump actuation, 0.2 mg/pump actuation
, Spray - Nasal, Nasal, Spray, Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered - Nasal, Spray, metered, Spray, metered - Nasal
Bronchoconstriction
0.05 mg, , 0.08 mg, 0.16 mg, 0.037 mg, 0.05 mg/pump actuation, 0.1 mg/pump actuation, 0.2 mg/pump actuation
, Spray - Nasal, Nasal, Spray, Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered - Nasal, Spray, metered, Spray, metered - Nasal
Chronic Obstructive Pulmonary Disease
0.05 mg, , 0.08 mg, 0.16 mg, 0.037 mg, 0.05 mg/pump actuation, 0.1 mg/pump actuation, 0.2 mg/pump actuation
, Spray - Nasal, Nasal, Spray, Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered - Nasal, Spray, metered, Spray, metered - Nasal
Hay Fever
0.05 mg, , 0.08 mg, 0.16 mg, 0.037 mg, 0.05 mg/pump actuation, 0.1 mg/pump actuation, 0.2 mg/pump actuation
, Spray - Nasal, Nasal, Spray, Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered - Nasal, Spray, metered, Spray, metered - Nasal
Rhinitis, Allergic
0.05 mg, , 0.08 mg, 0.16 mg, 0.037 mg, 0.05 mg/pump actuation, 0.1 mg/pump actuation, 0.2 mg/pump actuation
, Spray - Nasal, Nasal, Spray, Respiratory (inhalation), Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Aerosol, metered - Nasal, Spray, metered, Spray, metered - Nasal
Warnings
Zetonna has one prohibition. If you have any of the circumstances mentioned in the table below, Zetonna should not be taken.Zetonna ContraindicationsCondition
Risk Level
Notes
Status Asthmaticus
Do Not Combine
Common Zetonna Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Ciclesonide is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Ciclesonide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abetimus
Major
The risk or severity of adverse effects can be increased when Ciclesonide is combined with Abetimus.
Acteoside
Major
The risk or severity of adverse effects can be increased when Ciclesonide is combined with Acteoside.
Aldesleukin
Major
The therapeutic efficacy of Aldesleukin can be decreased when used in combination with Ciclesonide.
Zetonna Novel Uses: Which Conditions Have a Clinical Trial Featuring Zetonna?
245 active studies are being conducted to investigate the possible utility of Zetonna in alleviating Chronic Obstructive Pulmonary Disease (COPD), Asthma and Perennial Allergic Rhinitis (PAR).Condition
Clinical Trials
Trial Phases
Asthma
97 Actively Recruiting
Phase 4, Not Applicable, Early Phase 1, Phase 2, Phase 3, Phase 1
Hay Fever
0 Actively Recruiting
Rhinitis, Allergic
0 Actively Recruiting
Bronchoconstriction
0 Actively Recruiting
Chronic Obstructive Pulmonary Disease
84 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4
Zetonna Reviews: What are patients saying about Zetonna?
5Patient Review
6/6/2013 I was really struggling before I found this medication. I had tried everything over-the-counter, and nothing worked. This has been a life saver.
5Patient Review
1/4/2014 I've used a lot of different nasal sprays, and this is by far the best one I've tried. It's long lasting and effective.
5Patient Review
2/15/2015 Finally, after years of struggling and multiple sinus surgeries, I found a product that actually relieves the pressure in my sinuses. This medication is easy to use and really gets into your nasal cavities so they can drain properly. After using it for a month, I actually feel pretty good!
5Patient Review
9/17/2014 The quality of this product is excellent, but the price is unfortunately quite high. Even with insurance, I was paying almost $41 a month.
4.3Patient Review
4/30/2013 I had used over-the-counter nasal sprays for many years before I decided to give this a try. The active ingredient seems to help without the associated permanent tissue damage that I saw with prolonged use of the other stuff. It does burn when applied, but that's a minor complaint in comparison to the others.
4.3Patient Review
10/12/2015 I was hesitant to try this nasal inhaler at first, but my doctor convinced me. I'm glad I did! After a month of using it as directed, I noticed a significant difference in the swelling and irritation in my nose during ragweed season. Just be warned that you won't see results after only a week; give it some time to work its magic!
4Patient Review
11/11/2013 Zetonna nasl has really helped me. I used to get sick a lot, but now I feel much better. The only downside is that it's a bit drying and you have to squirt it up your nose, but it's worth it because I can breathe easier and my sinuses rarely feel clogged.
3.7Patient Review
5/4/2013 So far, so good. I've only been using this for four days, but I'm a little worried about the long-term effects of spraying directly onto my septum as per the instructions.
2.7Patient Review
8/8/2014 I've used this drug a few times, and every time I have, I get these strange headaches that are incredibly painful. They float around at the back of my head and haven't gone away for weeks now. I'm concerned about long term effects of this medication.
1.7Patient Review
11/23/2013 Every single time I use this medication, it burns terribly. It's so bad that it makes my eyes water. I've tried different angles and distances, but nothing seems to help. I don't know how much longer I can keep using it.
Patient Q&A Section about zetonna
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Zetonna a steroid?
"Zetonna is a steroid that prevents the release of inflammation-causing substances in the body. It is available as a nasal spray and is used to treat nasal symptoms (congestion, sneezing, runny nose) caused by seasonal allergies in adults and children as young as 6 years old."
Answered by AI
What is Zetonna used for?
"Ciclesonide is used to relieve allergy symptoms of the nose such as stuffy/runny nose, itching, and sneezing. It belongs to a class of drugs known as corticosteroids, which work by reducing swelling (inflammation) in the nasal passages."
Answered by AI
How much does Zetonna cost?
"The average retail price of Zetonna is $263.38, but the lowest GoodRx price is around $225.49, which is 14% off the average retail price."
Answered by AI
What is Zetonna nasal spray?
"Zetonna is a corticosteroid that is indicated for the treatment of symptoms associated with seasonal and perennial allergic rhinitis in adults and adolescents 12 years of age or older."
Answered by AI