Vitamin D Supplementation for Foot and Ankle Surgery

Recruiting in Palo Alto (17 mi)

+1 other location

Overseen byRebecca Senehi, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase < 1

Waitlist Available

Sponsor: Prisma Health-Midlands

No Placebo Group

Approved in 6 Jurisdictions

Trial Summary

What is the purpose of this trial?Vitamin D is important for bone health and recent research has emphasized the importance of adequate vitamin D levels for bone healing, wound healing, and possibly preventing infections post-operatively. This study will assess the effect of vitamin D supplementation on patient outcomes following ankle arthrodesis or first metatarsophalangeal joint arthrodesis.

Eligibility Criteria

This trial is for adults over 18 who are having ankle or big toe joint fusion surgery and can communicate in English. It's not open to those under 18, with active joint infections, unable to consent, or prisoners.

Inclusion Criteria

I am 18 years old or older.

Subject speaks and understands English

I am having surgery to fuse bones in my ankle or big toe.

Exclusion Criteria

Subject is a prisoner

I am unable to give consent by myself.

I am under 18 years old.

+1 more

Participant Groups

The study is testing if taking Vitamin D3 supplements helps improve bone healing, wound recovery, and prevent infections after foot-related fusion surgeries like ankle arthrodesis or metatarsophalangeal (big toe) joint arthrodesis.

2Treatment groups

Experimental Treatment

Active Control

Group I: Vitamin D Supplementation GroupExperimental Treatment1 Intervention

Patients enrolled in the Vitamin D Supplementation Group will receive 50,000 IU Vitamin D3 weekly for 8 weeks.

Group II: Control GroupActive Control1 Intervention

Patients enrolled in the control group will receive standard of care.